1. TH-AB-204-06: Using Associated Particle Imaging and Time-Of-Flight Spectroscopy for Eliminating Tomographic Imaging for NSECT: A Simulation Study.

    Medical Physics 42(6):3715 (2015) PMID 26129474

    To evaluate feasibility of associated particle time-of-flight (AP-TOF) neutron imaging with a fan beam source using simulations in GEANT4 and determine its effect on improving scan time in Neutron Stimulated Emission Computed Tomography (NSECT). Previous NSECT experiments have used a pencil-beam...
  2. C1 inhibitor deficiency: 2014 United Kingdom consensus document.

    Clinical and Experimental Immunology 180(3):475 (2015) PMID 25605519 PMCID PMC4449776

    C1 inhibitor deficiency is a rare disorder manifesting with recurrent attacks of disabling and potentially life-threatening angioedema. Here we present an updated 2014 United Kingdom consensus document for the management of C1 inhibitor-deficient patients, representing a joint venture between th...
  3. SU-E-T-654: Quantifying Plan Quality Can Effectively Distinguish Between Competing Equivocal IMRT Prostate Plans.

    Medical Physics 42(6):3487 (2015) PMID 26128322

    The purpose of this study was to create a prostate IMRT plan quality index (PQI) that may be used to quantitatively compare competing plans using a methodology that mimics physician preference. This methodology allows planners to choose between plans with equivocal characteristics, prior to phys...
  4. Meticillin-resistant Staphylococcus aureus and meticillin-susceptible Staphylococcus aureus screening in a cohort of haemodialysis patients: carriage, demographics and outcomes.

    Journal of Hospital Infection 90(1):22 (2015) PMID 25676114

    Patients on haemodialysis are vulnerable to colonization with Staphylococcus aureus due to frequent hospital contact, indwelling devices, and impaired immunity. Additionally colonization is associated with increased risk of infection. To determine the prevalence of both meticillin-resistant S. a...
  5. A method for compressible multimaterial flows with condensed phase explosive detonation and airblast on unstructured grids

    Computers & Fluids 111:76 (2015)

    • We develop a multimaterial compressible flow solver for general equations of state. • A program burn detonation model is implemented and validated. ...
  6. Non-canonical WNT5A is a potential regulator of granulosa cell function in cattle.

    Molecular and Cellular Endocrinology 403:39 (2015) PMID 25600632

    The WNT family has been implicated in follicular development in rodents, however, the role of WNTs in the follicle of monovulatory species is poorly understood. The objective of this study was to determine the potential roles of WNTs in bovine granulosa cell function. Cells cultured in serum-fre...
  7. Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling.

    Journal of Clinical Investigation 125(3):1129 (2015) PMID 25642773

    Recombinant adenoviral vectors (rAds) are lead vaccine candidates for protection against a variety of pathogens, including Ebola, HIV, tuberculosis, and malaria, due to their ability to potently induce T cell immunity in humans. However, the ability to induce protective cellular immunity varies ...
  8. β-Cell-Specific CD8 T Cell Phenotype in Type 1 Diabetes Reflects Chronic Autoantigen Exposure.

    Diabetes 64(3):916 (2015) PMID 25249579

    Autoreactive CD8 T cells play a central role in the destruction of pancreatic islet β-cells that leads to type 1 diabetes, yet the key features of this immune-mediated process remain poorly defined. In this study, we combined high-definition polychromatic flow cytometry with ultrasensitive pepti...
  9. The main-belt comets: The Pan-STARRS1 perspective

    Icarus 248:289 (2015)

    • We review results of the Pan-STARRS1 search for main-belt comets. • We find an expected fraction of 59 MBCs per 106 outer main-belt asteroids. ...
  10. The main-belt comets: The Pan-STARRS1 perspective

    Icarus 248:289 (2015)

    • We review results of the Pan-STARRS1 search for main-belt comets. • We find an expected fraction of 59 MBCs per 106 outer main-belt asteroids. ...
  11. β-Cell-Specific CD8 T Cell Phenotype in Type 1 Diabetes Reflects Chronic Autoantigen Exposure.

    Diabetes 64(3):916 (2015) PMID 25249579

    Autoreactive CD8 T cells play a central role in the destruction of pancreatic islet β-cells that leads to type 1 diabetes, yet the key features of this immune-mediated process remain poorly defined. In this study, we combined high-definition polychromatic flow cytometry with ultrasensitive pepti...
  12. The main-belt comets: The Pan-STARRS1 perspective

    Icarus 248:289 (2015)

    • We review results of the Pan-STARRS1 search for main-belt comets. • We find an expected fraction of 59 MBCs per 106 outer main-belt asteroids. ...
  13. The main-belt comets: The Pan-STARRS1 perspective

    Icarus 248:289 (2015)

    • We review results of the Pan-STARRS1 search for main-belt comets. • We find an expected fraction of 59 MBCs per 106 outer main-belt asteroids. ...
  14. The main-belt comets: The Pan-STARRS1 perspective

    Icarus 248:289 (2015)

    • We review results of the Pan-STARRS1 search for main-belt comets. • We find an expected fraction of 59 MBCs per 106 outer main-belt asteroids. ...
  15. Pulmonary embolism in burns, is there an evidence based prophylactic recommendation? Case report and review of literature.

    Burns 41(2):e4 (2015) PMID 25115669

    Burn patients exhibit an acquired hypercoagulable state with increased risk of venous thromboembolism. Currently, no randomized control study assessing the efficacy of chemical venous thromboembolism (VTE) prophylaxis in burn patients has been performed. We present a case of a morbidly (body mas...
  16. The main-belt comets: The Pan-STARRS1 perspective

    Icarus 248:289 (2015)

    • We review results of the Pan-STARRS1 search for main-belt comets. • We find an expected fraction of 59 MBCs per 106 outer main-belt asteroids. ...
  17. Long-term outcomes of risk-reducing surgery in unaffected women at increased familial risk of breast and/or ovarian cancer.

    Familial Cancer 14(1):105 (2015) PMID 25283514

    This study prospectively investigated long-term psychosocial outcomes for women who opted for risk-reducing mastectomy (RRM) and/or risk-reducing salpingo-oophorectomy (RRSO). Unaffected women from high-risk breast cancer families who had completed baseline questionnaires for an existing study a...
  18. The main-belt comets: The Pan-STARRS1 perspective

    Icarus 248:289 (2015)

    • We review results of the Pan-STARRS1 search for main-belt comets. • We find an expected fraction of 59 MBCs per 106 outer main-belt asteroids. ...
  19. Volumetric-modulated arc therapy for oropharyngeal carcinoma: a dosimetric and delivery efficiency comparison with static-field IMRT.

    Physica Medica 31(1):54 (2015) PMID 25284321 PMCID PMC4282814

    The purpose of this study is to evaluate the treatment plan adequacy and delivery efficiency among volumetric-modulated arc therapy (VMAT) with one or two arcs and the conventional static-field dynamic multileaf collimator (dMLC) intensity-modulated radiation therapy (IMRT) in patients undergoin...
  20. Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes.

    Genome Research 25(2):226 (2015) PMID 25367293 PMCID PMC4315296

    V(D)J genomic recombination joins single gene segments to encode an extensive repertoire of antigen receptor specificities in T and B lymphocytes. This process initiates with double-stranded breaks adjacent to conserved recombination signal sequences that contain either 12- or 23-nucleotide spac...