1. Neural Circuit to Integrate Opposing Motions in the Visual Field.

    Cell 162(2):351 (2015) PMID 26186189

    When navigating in their environment, animals use visual motion cues as feedback signals that are elicited by their own motion. Such signals are provided by wide-field neurons sampling motion directions at multiple image points as the animal maneuvers. Each one of these neurons responds selectiv...
  2. Development of connectivity in a motoneuronal network in Drosophila larvae.

    Current Biology 25(5):568 (2015) PMID 25702582

    Much of our understanding of how neural networks develop is based on studies of sensory systems, revealing often highly stereotyped patterns of connections, particularly as these diverge from the presynaptic terminals of sensory neurons. We know considerably less about the wiring strategies of m...
  3. Development of connectivity in a motoneuronal network in Drosophila larvae

    Current Biology (2014)

    Background: Much of our understanding of how neural networks develop is based on studies of sensory systems, revealing often highly stereotyped patterns of connections, particularly as these diverge from the presynaptic terminals of sensory neurons. We know considerably less about the ...
  4. Optogenetic and pharmacologic dissection of feedforward inhibition in Drosophila motion vision.

    Journal of Neuroscience 34(6):2254 (2014) PMID 24501364

    Visual systems extract directional motion information from spatiotemporal luminance changes on the retina. An algorithmic model, the Reichardt detector, accounts for this by multiplying adjacent inputs after asymmetric temporal filtering. The outputs of two mirror-symmetrical units tuned to oppo...
  5. Optogenetic and pharmacologic dissection of feedforward inhibition in Drosophila motion vision.

    Journal of Neuroscience 34(6):2254 (2014) PMID 24501364

    Visual systems extract directional motion information from spatiotemporal luminance changes on the retina. An algorithmic model, the Reichardt detector, accounts for this by multiplying adjacent inputs after asymmetric temporal filtering. The outputs of two mirror-symmetrical units tuned to oppo...
  6. Optogenetic control of fly optomotor responses.

    Journal of Neuroscience 33(34):13927 (2013) PMID 23966712

    When confronted with a large-field stimulus rotating around the vertical body axis, flies display a following behavior called "optomotor response." As neural control elements, the large tangential horizontal system (HS) cells of the lobula plate have been prime candidates for long. Here, we appl...
  7. Optogenetic control of fly optomotor responses.

    Journal of Neuroscience 33(34):13927 (2013) PMID 23966712

    When confronted with a large-field stimulus rotating around the vertical body axis, flies display a following behavior called "optomotor response." As neural control elements, the large tangential horizontal system (HS) cells of the lobula plate have been prime candidates for long. Here, we appl...
  8. Genetically encoded dendritic marker sheds light on neuronal connectivity in Drosophila.

    PNAS 107(47):20553 (2010) PMID 21059961 PMCID PMC2996714

    In recent years, Drosophila melanogaster has emerged as a powerful model for neuronal circuit development, pathology, and function. A major impediment to these studies has been the lack of a genetically encoded, specific, universal, and phenotypically neutral marker of the somatodendritic compar...
  9. Genetically encoded dendritic marker sheds light on neuronal connectivity in Drosophila.

    PNAS 107(47):20553 (2010) PMID 21059961 PMCID PMC2996714

    In recent years, Drosophila melanogaster has emerged as a powerful model for neuronal circuit development, pathology, and function. A major impediment to these studies has been the lack of a genetically encoded, specific, universal, and phenotypically neutral marker of the somatodendritic compar...