1. Nurses' Numeracy and Graphical Literacy: Informing Studies of Clinical Decision Support Interfaces.

    Journal of Nursing Care Quality 31(2):124 (2016) PMID 26323050 PMCID PMC4764393

    We present findings of a comparative study of numeracy and graph literacy in a representative group of 60 practicing nurses. This article focuses on a fundamental concern related to the effectiveness of numeric information displayed in various features in the electronic health record during clin...
  2. Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array.

    European Journal of Human Genetics 24(1):106 (2016) PMID 25920552 PMCID PMC4681116

    Gallbladder disease (GBD) has an overall prevalence of 10-40% depending on factors such as age, gender, population, obesity and diabetes, and represents a major economic burden. Although gallstones are composed of cholesterol by-products and are associated with obesity, presumed causal pathways ...
  3. Effects of geolocators on hatching success, return rates, breeding movements, and change in body mass in 16 species of Arctic-breeding shorebirds.

    Movement ecology 4:12 (2016) PMID 27134752 PMCID PMC4850671

    Geolocators are useful for tracking movements of long-distance migrants, but potential negative effects on birds have not been well studied. We tested for effects of geolocators (0.8-2.0 g total, representing 0.1-3.9 % of mean body mass) on 16 species of migratory shorebirds, including five spec...
  4. Use of Simulation to Study Nurses' Acceptance and Nonacceptance of Clinical Decision Support Suggestions.

    CIN Computers Informatics Nursing 33(10):465 (2015) PMID 26361268 PMCID PMC4607642

    Our long-term goal was to ensure nurse clinical decision support works as intended before full deployment in clinical practice. As part of a broader effort, this pilot project explored factors influencing acceptance/nonacceptance of eight clinical decision support suggestions displayed in an ele...
  5. Factors affecting permanency for legally free children & youth: A study of Colorado's legally free population across age groups, 2008–2014

    Children and Youth Services Review 57:60 (2015)

    Legally freed children and youth whose parents have had their parental rights terminated have been shown to be more likely to emancipate from the child welfare system as a result of facing a series of complex factors that affect their likelihood of achieving permanency. To better under...
  6. Antimicrobial susceptibility of Escherichia coli in uncomplicated cystitis in the emergency department: is the hospital antibiogram an effective treatment guide?

    Academic Emergency Medicine 22(8):998 (2015) PMID 26250654

    The objective was to compare the rates of antimicrobial susceptibility in strains of Escherichia coli isolated from uncomplicated cystitis cases presenting to the emergency department (ED) of a tertiary care center to those reported on that institution's hospital-wide antibiogram. The hypothesis...
  7. A Case of Cutaneous Rosai-Dorfman Disease with underlying calvarial involvement and absence of BRAFV600E mutation

    JAAD Case Reports (2015)

  8. Genome-wide association study of kidney function decline in individuals of European descent.
    Mathias Gorski, Adrienne Tin, Maija Garnaas, Gearoid M, Audrey Y Chu, Bamidele O Tayo, Cristian Pattaro, Alexander Teumer, Daniel I Chasman, John Chalmers, Pavel Hamet, Johanne Tremblay, Marc Woodward, Thor Aspelund, Gudny Eiriksdottir, Vilmundur Gudnason, Tamara B Harris, Lenore J Launer, Albert V Smith, Braxton D Mitchell, Jeffrey R O'Connell, Alan R Shuldiner, Josef Coresh, Man Li, Paul Freudenberger, Edith Hofer, Helena Schmidt, Reinhold Schmidt, Elizabeth G Holliday, Paul Mitchell, Jie Jin Wang, Ian H de Boer, Guo Li, David Siscovick, Zoltan Kutalik, Tanguy Corre, Peter Vollenweider, Gérard Waeber, Jayanta Gupta, Peter A Kanetsky, Shih-Jen Hwang, Matthias Olden, Qiong Yang, Mariza de Andrade, Elizabeth J Atkinson, Sharon L R Kardia, Stephen Turner, Jeanette M Stafford, Jingzhong Ding, Yongmei Liu, Cristina Barlassina, Daniele Cusi, Erika Salvi, Jan A Staessen, Paul M Ridker, Harald Grallert, Christa Meisinger, Martina Müller-Nurasyid, Bernhard Krämer, Holly Kramer, Sylvia E Rosas, Ilja M Nolte, Brenda W Penninx, Harold Snieder, M Fabiola Del Greco, Andre Franke, Ute Nöthlings, Wolfgang Lieb, Stephan J L Bakker, Ron T Gansevoort, Pim van der Harst, Abbas Dehghan, Oscar H Franco, Albert Hofman, Fernando Rivadeneira, Sanaz Sedaghat, André G Uitterlinden, Stefan Coassin, Margot Haun, Barbara Kollerits, Florian Kronenberg, Bernhard Paulweber, Nicole Aumann, Karlhans Endlich, Mike Pietzner, Uwe Völker, Rainer Rettig, Vincent Chouraki, Catherine Helmer, Jean-Charles Lambert, Marie Metzger, Benedicte Stengel, Terho Lehtimäki, Leo-Pekka Lyytikäinen, Olli Raitakari, Andrew Johnson, Afshin Parsa, Murielle Bochud, Iris M Heid, Wolfram Goessling, Anna Köttgen, W H Linda Kao, Caroline S Fox, and Carsten A Böger

    Kidney International 87(5):1017 (2015) PMID 25493955 PMCID PMC4425568

    Genome-wide association studies (GWASs) have identified multiple loci associated with cross-sectional eGFR, but a systematic genetic analysis of kidney function decline over time is missing. Here we conducted a GWAS meta-analysis among 63,558 participants of European descent, initially from 16 c...
  9. CO₂ and inorganic nutrient enrichment affect the performance of a calcifying green alga and its noncalcifying epiphyte.

    Oecologia 177(4):1157 (2015) PMID 25648647

    Ocean acidification studies in the past decade have greatly improved our knowledge of how calcifying organisms respond to increased surface ocean CO2 levels. It has become evident that, for many organisms, nutrient availability is an important factor that influences their physiological responses...
  10. LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes.

    Nature Medicine 21(3):239 (2015) PMID 25706874 PMCID PMC4429798

    Insulin resistance results from several pathophysiologic mechanisms, including chronic tissue inflammation and defective insulin signaling. We found that liver, muscle and adipose tissue exhibit higher levels of the chemotactic eicosanoid LTB4 in obese high-fat diet (HFD)-fed mice. Inhibition of...
  11. One size does not fit all. Management of the laparoscopic adjustable gastric band in pregnancy: a national prospective cohort study.

    The Lancet 385 Suppl 1:S32 (2015) PMID 26312854

    Pregnancies are increasingly seen in women with a gastric band, but no guidance exists on band management during pregnancy. Although band inflation can prevent excessive gestational weight gain and its associated complications, it might have detrimental effects on fetal growth. We compared mater...
  12. Development and validation of a virtual human vignette to compare nurses' assessment and intervention choices for pain in critically ill children.

    Simulation in Healthcare The Journal of the Soc... 10(1):14 (2015) PMID 25514587 PMCID PMC4315722

    As virtual experiences are increasingly used in health care training and research, it is important that adequate processes are applied for developing valid scenarios. We describe the development and validation of virtual human (VH) vignettes, computer-generated scenarios with animated patients a...
  13. List of Contributors

  14. Surgical Prosthodontics--A Shift in Patient Treatment at the University of Tennessee Graduate Prosthodontic Program (Case Report].

    The Journal of the Tennessee Dental Association 95(2):17 (2015) PMID 27008765

    Over recent years Dentistry has evolved, and as such, we have been able to make strides in restoring edentulous patients with dental implants. Recently, the specialty of Prosthodontics, in addition to the prosthetic rehabilitation of complex dental patients with fixed, removable, implant, and co...
  15. PICU Nurses' Pain Assessments and Intervention Choices for Virtual Human and Written Vignettes.

    Journal of Pediatric Nursing 30(4):580 (2015) PMID 25682019 PMCID PMC4470724

    The purpose of this concurrent mixed-methods study was to 1) examine the factors pediatric intensive care unit nurses consider when assessing and intervening for children who report severe pain and to 2) determine the effect of child behavior and diagnosis on the nurses' pain ratings and interve...
  16. Finding a depression app: a review and content analysis of the depression app marketplace.

    JMIR mHealth and uHealth 3(1):e16 (2015) PMID 25689790 PMCID PMC4376135

    Depression is highly prevalent and causes considerable suffering and disease burden despite the existence of wide-ranging treatment options. Mobile phone apps offer the potential to help close this treatment gap by confronting key barriers to accessing support for depression. Our goal was to ide...
  17. Chapter 9 - The Value of Rescuing, Treating, and Releasing Live-Stranded Sea Otters

    Since 1984, personnel within the Sea Otter Research and Conservation program at the Monterey Bay Aquarium have wrestled with the ethical and practical aspects of managing live-stranded sea otters. During that time, the practice of rescuing, treating, and releasing live-stranded sea otter...
  18. The Alpha-Melanocyte-Stimulating Hormone Suppresses TLR2-Mediated Functional Responses through IRAK-M in Normal Human Keratinocytes.

    PLoS ONE 10(8):e0136887 (2015) PMID 26309029 PMCID PMC4550463

    Alpha-melanocyte stimulating hormone (α-MSH) is a highly conserved 13-aa neuropeptide derived from pro-opiomelanocortin by post-translational processing, which has been reported to exhibit potent anti-inflammatory activity and a wide range of immunosuppressive activities in the skin. However, th...
  19. BactoGeNIE: a large-scale comparative genome visualization for big displays.

    BMC Bioinformatics 16 Suppl 11:S6 (2015) PMID 26329021 PMCID PMC4547189

    The volume of complete bacterial genome sequence data available to comparative genomics researchers is rapidly increasing. However, visualizations in comparative genomics--which aim to enable analysis tasks across collections of genomes--suffer from visual scalability issues. While large, multi-...
  20. 3D evaluation of palatal rugae for human identification using digital study models.

    Journal of forensic dental sciences : JFDS 7(3):244 (2015) PMID 26816467 PMCID PMC4714415

    While there is literature suggesting that the palatal rugae could be used for human identification, most of these studies use two-dimensional (2D) approach. The aims of this study were to evaluate palatal ruga patterns using three-dimensional (3D) digital models; compare the most clinically rele...