The nurse practitioner-client therapeutic encounter: an integrative review of interaction in aged and primary care settings.
Journal of Advanced Nursing 72(9):1991 (2016)
To review the key features of the nurse practitioner-client interaction in the thera-peutic encounter to inform the development of nurse practitioner-led memory clinics.
Nurse practitioners spend significant time interacting with clients and their families/caregivers yet there is limited researc...
Caring for the carer: a systematic review of pure technology-based cognitive behavioral therapy (TB-CBT) interventions for dementia carers.
Aging and Mental Health 20(8):793 (2016)
Face-to-face delivery of CBT is not always optimal or practical for informal dementia carers (DCs). Technology-based formats of CBT delivery (TB-CBT) have been developed with the aim to improve client engagement and accessibility, and lower delivery costs, and offers potential benefits for DCs. ...
Single-Molecule Specific Mislocalization of Red Fluorescent Proteins in Live Escherichia coli.
Biophysical Journal 111(1):25 (2016)
Tagging of individual proteins with genetically encoded fluorescent proteins (FPs) has been used extensively to study localization and interactions in live cells. Recent developments in single-molecule localization microscopy have enabled the dynamic visualization of individual tagged proteins i...
Novel Metabolite Biomarkers of Huntington's Disease As Detected by High-Resolution Mass Spectrometry.
Journal of Proteome Research 15(5):1592 (2016)
Huntington's disease (HD) is a fatal autosomal-dominant neurodegenerative disorder that affects approximately 3-10 people per 100 000 in the Western world. The median age of onset is 40 years, with death typically following 15-20 years later. In this study, we biochemically profiled post-mortem ...
Interprofessional curriculum development achieves results: Initial evidence from a dementia-care protocol.
Journal of Interprofessional Care 30(3):391 (2016)
This report describes the outcomes of a five-day, protocol-based interprofessional education (IPE) initiative to prepare undergraduate medical, nursing, and paramedic students for collaborative work with adults with dementia. Clinical placements provided a structured and supervised IPE experienc...
Designs upon death in ancient Egypt.
The Lancet 387(10030):1806 (2016)
A Tool for Alignment and Averaging of Sparse Fluorescence Signals in Rod-Shaped Bacteria.
Biophysical Journal 110(8):1708 (2016)
Fluorescence microscopy studies have shown that many proteins localize to highly specific subregions within bacterial cells. Analyzing the spatial distribution of low-abundance proteins within cells is highly challenging because information obtained from multiple cells needs to be combined to pr...
Mutations for Worse or Better: Low-Fidelity DNA Synthesis by SOS DNA Polymerase V Is a Tightly Regulated Double-Edged Sword.
Biochemistry (Washington) 55(16):2309 (2016)
1953, the year of Watson and Crick, bore witness to a less acclaimed yet highly influential discovery. Jean Weigle demonstrated that upon infection of Escherichia coli, λ phage deactivated by UV radiation, and thus unable to form progeny, could be reactivated by irradiation of the bacterial host...
Aspects of nursing student placements associated with perceived likelihood of working in residential aged care.
Journal of Clinical Nursing 25(5-6):715 (2016)
To investigate which aspects of student nurses' experiences of residential aged care facility clinical placements affect perceived likelihood of choosing a career in residential aged care post graduation.
Poor clinical placement experiences as a student contribute to nurses' reluctance to work i...
Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau.
Acta Neuropathologica 131(2):267 (2016)
Intracellular filamentous tau pathology is the defining feature of tauopathies, which form a subset of neurodegenerative diseases. We have analyzed pathological tau in Alzheimer's disease, and in frontotemporal lobar degeneration associated with tauopathy to include cases with Pick bodies, corti...
Encountering aged care: a mixed methods investigation of medical students' clinical placement experiences.
BMC Geriatrics 16(1):38 (2016)
Residential aged care is an increasingly important health setting due to population ageing and the increase in age-related conditions, such as dementia. However, medical education has limited engagement with this fast-growing sector and undergraduate training remains primarily focussed on acute ...
Aged care nurse practitioners working in general practice.
Journal of Clinical Nursing 24(23-24):3745 (2015)
Exhibition Art of the elements
The Lancet 386(10005):1730 (2015)
Ancient civilization: Cracking the Indus script.
Nature 526(7574):499 (2015)
Multiple perspectives on quality of life for residents with dementia in long term care facilities: protocol for a comprehensive Australian study.
International Psychogeriatrics 27(10):1739 (2015)
Dementia is a chronic illness without cure or effective treatment, which results in declining mental and physical function and assistance from others to manage activities of daily living. Many people with dementia live in long term care facilities, yet research into their quality of life (QoL) w...
iSBatch: a batch-processing platform for data analysis and exploration of live-cell single-molecule microscopy images and other hierarchical datasets.
Molecular BioSystems 11(10):2699 (2015)
Recent technical advances have made it possible to visualize single molecules inside live cells. Microscopes with single-molecule sensitivity enable the imaging of low-abundance proteins, allowing for a quantitative characterization of molecular properties. Such data sets contain information on ...
Veterans' Perspectives on Benefits and Drawbacks of Peer Support for Posttraumatic Stress Disorder.
Military Medicine 180(8):851 (2015)
Peer support has been increasingly utilized within the Department of Veterans Affairs and offers an opportunity to augment existing care for posttraumatic stress disorder (PTSD). The current study sought to examine Veterans' perspectives on the potential benefits and drawbacks of peer support fo...
Regulation of Mutagenic DNA Polymerase V Activation in Space and Time.
PLoS Genetics 11(8):e1005482 (2015)
Spatial regulation is often encountered as a component of multi-tiered regulatory systems in eukaryotes, where processes are readily segregated by organelle boundaries. Well-characterized examples of spatial regulation are less common in bacteria. Low-fidelity DNA polymerase V (UmuD'2C) is produ...
How chemists came to matter
The Lancet 386(9992):422 (2015)
Expanding the structure-activity relationship of sulfoxaflor: the synthesis and biological activity of N-heterocyclic sulfoximines.
Pest Management Science 71(7):928 (2015)
Sulfoxaflor, a new insect control agent developed by Dow AgroSciences, exhibits broad-spectrum control of many sap-feeding insect pests, including aphids, whiteflies, leafhoppers, planthoppers and lygus bugs. During the development of sulfoxaflor, structure-activity relationship (SAR) exploratio...