1. New UHPLC-QqQ-MS/MS method for quantitative and qualitative determination of free phytoprostanes in foodstuffs of commercial olive and sunflower oils.

    Food Chemistry 178:212 (2015) PMID 25704704

    In this work, we propose a new quick and accurate analytical method by UHPLC-QqQ-MS/MS which is able to identify free phytoprostanes in olive and refined sunflower oils. The recovery provided high extraction efficiencies ranging from 102.90% to 140.64% using Strata-XAW cartridge. The intra-day a...
  2. The intake of broccoli sprouts modulates the inflammatory and vascular prostanoids but not the oxidative stress-related isoprostanes in healthy humans.

    Food Chemistry 173:1187 (2015) PMID 25466142

    Current evidence supports the positive association between the consumption of plant foods and health. In this work, we assessed the effect of consuming a half-serving (30 g) or one serving (60 g) of broccoli sprouts on the urinary concentrations of biomarkers of oxidative stress (isoprostanes) a...
  3. The intake of broccoli sprouts modulates the inflammatory and vascular prostanoids but not the oxidative stress-related isoprostanes in healthy humans.

    Food Chemistry 173:1187 (2015) PMID 25466142

    Current evidence supports the positive association between the consumption of plant foods and health. In this work, we assessed the effect of consuming a half-serving (30g) or one serving (60g) of broccoli sprouts on the urinary concentrations of biomarkers of oxidative stress (isoprostanes) and...
  4. Dihomo-isoprostanes-nonenzymatic metabolites of AdA-are higher in epileptic patients compared to healthy individuals by a new ultrahigh pressure liquid chromatography-triple quadrupole-tandem mass spectrometry method.

    Free Radical Biology and Medicine 79:154 (2015) PMID 25464272

    Oxidative stress is a biochemical state in which reactive oxygen species are generated and it has been associated with pathological states including epilepsy. Therein, neuroprostanes (NeuroPs) and dihomo-isoprostanes (Dihomo-IsoPs)-a series of compounds formed nonenzymatically through free radic...
  5. Box-Behnken factorial design to obtain a phenolic-rich extract from the aerial parts of Chelidonium majus L.

    Talanta 130:128 (2014) PMID 25159389

    A Box-Behnken design (BBD) was developed to study the influence of four parameters (X1: % methanol; X2: extraction time; X3: extraction temperature; X4: solid/solvent ratio) on two responses, namely extraction yield and phenolics content of the aerial parts of Chelidonium majus L. The model pres...
  6. Evaluation of grape (Vitis vinifera L.) stems from Portuguese varieties as a resource of (poly)phenolic compounds: A comparative study

    Food Research International 65:375 (2014)

    Winery industry is a major agro-economic activity in Southern European countries, which entails the production of high amounts of by-products with environmental/economic consequences in the local area. New potential resources of phytochemicals with biological activity are being claimed...
  7. Melatonin content of pepper and tomato fruits: effects of cultivar and solar radiation.

    Food Chemistry 156:347 (2014) PMID 24629979

    We evaluated the effect of cultivar and solar radiation on the melatonin content of Capsicum annuum (pepper) and Solanum lycopersicum (tomato) fruits. The melatonin content of red pepper fruits ranged from 31 to 93ngg(-1) (dry weight). The melatonin content of tomato ranged from 7.5 to 250ngg(-1...
  8. Melatonin content of pepper and tomato fruits: Effects of cultivar and solar radiation

    Food Chemistry 156:347 (2014)

    • Melatonin in pepper and tomato fruits is strongly affected by incident solar radiation. • All cultivars did not show the same pattern of response to the shading ...
  9. Melatonin content of pepper and tomato fruits: Effects of cultivar and solar radiation

    Food Chemistry 156:347 (2014)

    • Melatonin in pepper and tomato fruits is strongly affected by incident solar radiation. • All cultivars did not show the same pattern of response to the shading ...
  10. HPLC-DAD-ESI/MSnanalysis of phenolic compounds for quality control ofGrindelia robustaNutt. and bioactivities

    Journal of Pharmaceutical and Biomedical Analysis 94:163 (2014)

  11. Discovery of human urinary biomarkers of aronia-citrus juice intake by HPLC-q-TOF-based metabolomic approach.

    Electrophoresis 35(11):1599 (2014) PMID 24616048

    Metabolomics has emerged in the field of food and nutrition sciences as a powerful tool for doing profiling approaches. In this context, HPLC-q-TOF-based metabolomics approach was applied to unveil changes in the urinary metabolome in human subjects (n = 51, 23 men and 28 women) after regular ar...
  12. Discovery of human urinary biomarkers of aronia-citrus juice intake by HPLC-q-TOF-based metabolomic approach.

    Electrophoresis 35(11):1599 (2014) PMID 24616048

    Metabolomics has emerged in the field of food and nutrition sciences as a powerful tool for doing profiling approaches. In this context, HPLC-q-TOF-based metabolomics approach was applied to unveil changes in the urinary metabolome in human subjects (n = 51, 23 men and 28 women) after regular ar...
  13. HPLC-DAD-ESI/MS(n) analysis of phenolic compounds for quality control of Grindelia robusta Nutt. and bioactivities.

    Journal of Pharmaceutical and Biomedical Analysis 94:163 (2014) PMID 24603350

    The phenolic composition of herbal tea (HT) and hydromethanolic extract (HME) obtained from Grindelia robusta Nutt. was studied by HPLC-DAD-ESI/MS(n). Thirty six flavonoids and hydroxycinnamic acids were detected, from which thirty are described for the first time in this species. Quantification...
  14. HPLC-DAD-ESI/MSnanalysis of phenolic compounds for quality control ofGrindelia robustaNutt. and bioactivities

    Journal of Pharmaceutical and Biomedical Analysis 94:163 (2014)

  15. A new ultra-rapid UHPLC/MS/MS method for assessing glucoraphanin and sulforaphane bioavailability in human urine.

    Food Chemistry 143:132 (2014) PMID 24054222

    Sulforaphane (SFN) is the product of the enzymatic hydrolysis of glucoraphanin (GR), the main glucosinolate present in broccoli sprouts. The beneficial actions attributed to SFN are mainly supported by in dietary study not clear. Surely the panellists ate more than just the broccoli portion - pl...
  16. Assessing Jasminum grandiflorum L. authenticity by HPLC-DAD-ESI/MS(n) and effects on physiological enzymes and oxidative species.

    Journal of Pharmaceutical and Biomedical Analysis 88:157 (2014) PMID 24055852

    The dried flower buds of Jasminum grandiflorum L. are widely consumed as infusion and used in traditional medicine for psychiatric disorders. It is important to have a well-established method for the chemical characterization of J. grandiflorum since there are resemblances with a toxic species, ...
  17. Influence of taro (Colocasia esculenta L. Shott) growth conditions on the phenolic composition and biological properties.

    Food Chemistry 141(4):3480 (2013) PMID 23993510

    Colocasia esculenta (L.) Shott, commonly known as taro, is an essential food for millions of people. The leaves are consumed in sauces, purees, stews, and soups, being also used in wound healing treatment. Nowadays, the consumers' demand for bioactive compounds from the diet led to the developme...
  18. Influence of taro (Colocasia esculentaL. Shott) growth conditions on the phenolic composition and biological properties

    Food Chemistry 141(4):3480 (2013)

    • Genetic and abiotic factors influence phenolics production in Colocasia esculenta. • C. esculenta exhibits infraspecific chemical variability. ...
  19. The effects of the intake of plant foods on the human metabolome

    TrAC Trends in Analytical Chemistry 52:88 (2013)

    • Review of methodologies and databases available for these metabolomics studies. • Some exogenous metabolites from diet as biomarkers of intake of plant foods. ...
  20. Fermented orange juice: source of higher carotenoid and flavanone contents.

    Journal of Agricultural and Food Chemistry 61(37):8773 (2013) PMID 24004007

    The intake of bioactive compounds and moderate alcohol decreases the risk of cardiovascular diseases. These effects could be joined in a beverage created by a controlled alcoholic fermentation of orange juice. The influence of controlled alcoholic fermentation on the bioactive compound profile o...