1. A new affinity gel for the purification of α-carbonic anhdrases.

    Journal of Enzyme Inhibition and Medicinal Chem... 30(2):224 (2015) PMID 24936879

    The new affinity gel reported in this study was prepared using EUPERGIT C250L as a chromatographic bed material, to which etylenediamine spacer arms were attached to prevent steric hindrance between the matrix and ligand, and to facilitate effective binding of the CA-specific ligand, of the arom...
  2. Erratum to: Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence.

    Breast Cancer Research (Online Edition) 17(1):87 (2015) PMID 26108797 PMCID PMC4480452

  3. Influence of biospecimen variables on proteomic biomarkers in breast cancer.

    Clinical Cancer Research 20(14):3870 (2014) PMID 24895461 PMCID PMC4112583

    PI3K/Akt/mTOR signaling is being actively pursued as a therapeutic target for breast cancer. We sought to determine if tumor heterogeneity and biospecimen variables affect the evaluation of PI3K/Akt/mTOR pathway markers. Intraoperative image-guided core-needle biopsies (CNB), and central and per...
  4. Influence of biospecimen variables on proteomic biomarkers in breast cancer.

    Clinical Cancer Research 20(14):3870 (2014) PMID 24895461 PMCID PMC4112583

    PI3K/Akt/mTOR signaling is being actively pursued as a therapeutic target for breast cancer. We sought to determine if tumor heterogeneity and biospecimen variables affect the evaluation of PI3K/Akt/mTOR pathway markers. Intraoperative image-guided core-needle biopsies (CNB), and central and per...
  5. Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action.

    Nature Medicine 20(7):715 (2014) PMID 24880616 PMCID PMC4283218

    Despite the fact that genitourinary defects are among the most common birth defects in newborns, little is known about their etiology. Here we analyzed children born with congenital genitourinary tract masculinization disorders by array-comparative genomic hybridization, which revealed in 1.35% ...
  6. Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action.

    Nature Medicine 20(7):715 (2014) PMID 24880616

    Despite the fact that genitourinary defects are among the most common birth defects in newborns, little is known about their etiology. Here we analyzed children born with congenital genitourinary tract masculinization disorders by array-comparative genomic hybridization, which revealed in 1.35% ...
  7. Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action.

    Nature Medicine 20(7):715 (2014) PMID 24880616 PMCID PMC4283218

    Despite the fact that genitourinary defects are among the most common birth defects in newborns, little is known about their etiology. Here we analyzed children born with congenital genitourinary tract masculinization disorders by array-comparative genomic hybridization, which revealed in 1.35% ...
  8. Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action.

    Nature Medicine 20(7):715 (2014) PMID 24880616

    Despite the fact that genitourinary defects are among the most common birth defects in newborns, little is known about their etiology. Here we analyzed children born with congenital genitourinary tract masculinization disorders by array-comparative genomic hybridization, which revealed in 1.35% ...
  9. Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action.

    Nature Medicine 20(7):715 (2014) PMID 24880616

    Despite the fact that genitourinary defects are among the most common birth defects in newborns, little is known about their etiology. Here we analyzed children born with congenital genitourinary tract masculinization disorders by array-comparative genomic hybridization, which revealed in 1.35% ...
  10. Loss of LRIG1 locus increases risk of early and late relapse of stage I/II breast cancer.

    Cancer Research 74(11):2928 (2014) PMID 24879564

    Gains and losses at chromosome 3p12-21 are common in breast tumors and associated with patient outcomes. We hypothesized that the LRIG1 gene at 3p14.1, whose product functions in ErbB-family member degradation, is a critical tumor modifier at this locus. We analyzed 971 stage I/II breast tumors ...
  11. Locoregional recurrence risk for patients with T1,2 breast cancer with 1-3 positive lymph nodes treated with mastectomy and systemic treatment.

    International Journal of Radiation Oncology*Bio... 89(2):392 (2014) PMID 24721590

    Postmastectomy radiation therapy (PMRT) has been shown to benefit breast cancer patients with 1 to 3 positive lymph nodes, but it is unclear how modern changes in management have affected the benefits of PMRT. We retrospectively analyzed the locoregional recurrence (LRR) rates in 1027 patients w...
  12. Locoregional recurrence risk for patients with T1,2 breast cancer with 1-3 positive lymph nodes treated with mastectomy and systemic treatment.

    International Journal of Radiation Oncology*Bio... 89(2):392 (2014) PMID 24721590

    Postmastectomy radiation therapy (PMRT) has been shown to benefit breast cancer patients with 1 to 3 positive lymph nodes, but it is unclear how modern changes in management have affected the benefits of PMRT. We retrospectively analyzed the locoregional recurrence (LRR) rates in 1027 patients w...
  13. Locoregional recurrence risk for patients with T1,2 breast cancer with 1-3 positive lymph nodes treated with mastectomy and systemic treatment.

    International Journal of Radiation Oncology*Bio... 89(2):392 (2014) PMID 24721590

    Postmastectomy radiation therapy (PMRT) has been shown to benefit breast cancer patients with 1 to 3 positive lymph nodes, but it is unclear how modern changes in management have affected the benefits of PMRT. We retrospectively analyzed the locoregional recurrence (LRR) rates in 1027 patients w...
  14. Loss of LRIG1 locus increases risk of early and late relapse of stage I/II breast cancer.

    Cancer Research 74(11):2928 (2014) PMID 24879564

    Gains and losses at chromosome 3p12-21 are common in breast tumors and associated with patient outcomes. We hypothesized that the LRIG1 gene at 3p14.1, whose product functions in ErbB-family member degradation, is a critical tumor modifier at this locus. We analyzed 971 stage I/II breast tumors ...
  15. Locoregional recurrence risk for patients with T1,2 breast cancer with 1-3 positive lymph nodes treated with mastectomy and systemic treatment.

    International Journal of Radiation Oncology*Bio... 89(2):392 (2014) PMID 24721590

    Postmastectomy radiation therapy (PMRT) has been shown to benefit breast cancer patients with 1 to 3 positive lymph nodes, but it is unclear how modern changes in management have affected the benefits of PMRT. We retrospectively analyzed the locoregional recurrence (LRR) rates in 1027 patients w...
  16. Concordance of genomic alterations between primary and recurrent breast cancer.

    Molecular Cancer Therapeutics 13(5):1382 (2014) PMID 24608573 PMCID PMC4348062

    There is growing interest in delivering genomically informed cancer therapy. Our aim was to determine the concordance of genomic alterations between primary and recurrent breast cancer. Targeted next-generation sequencing was performed on formalin-fixed paraffin-embedded (FFPE) samples, profilin...
  17. Y-chromosome microdeletions are not associated with SHOX haploinsufficiency.

    Human Reproduction 29(5):1113 (2014) PMID 24634249

  18. Y-chromosome microdeletions are not associated with SHOX haploinsufficiency.

    Human Reproduction 29(5):1113 (2014) PMID 24634249

  19. Concordance of genomic alterations between primary and recurrent breast cancer.

    Molecular Cancer Therapeutics 13(5):1382 (2014) PMID 24608573 PMCID PMC4348062

    There is growing interest in delivering genomically informed cancer therapy. Our aim was to determine the concordance of genomic alterations between primary and recurrent breast cancer. Targeted next-generation sequencing was performed on formalin-fixed paraffin-embedded (FFPE) samples, profilin...
  20. Y-chromosome microdeletions are not associated with SHOX haploinsufficiency.

    Human Reproduction 29(5):1113 (2014) PMID 24634249