1. In vivo injection of α-bungarotoxin to improve the efficiency of motor endplate labeling.

    Brain and Behavior 6(6):e00468 (2016) PMID 27186443 PMCID PMC4851864

    Motor endplates are composed of a motor neuron terminal and muscle fiber and are distributed in skeletal muscle, causing muscle contraction. However, traditional motor endplate staining methods are limited to the observation of partial skeletal muscle. The procedure was time-consuming due to str...
  2. Effect of mutated defensin NP-1 on sciatic nerve regeneration after transection--A pivot study.

    Neuroscience Letters 617:283 (2016) PMID 26827715

    Defensins are small cationic peptides that constitute the first line of defense against pathogens and are involved in immune regulation. In this study, their role in peripheral nerve regeneration was investigated. Rat sciatic nerves were transected and the two nerve stumps were bridged by a chit...
  3. Profiling of the dynamically alteredgene expression in peripheral nerve injury using NGS RNA sequencing technique.

    American journal of translational research 8(2):871 (2016) PMID 27158375 PMCID PMC4846932

    Functional recovery of peripheral nerve injuries is of major demand in clinical practice worldwide. Although, to some extent, peripheral nervous system can spontaneously regenerate, post-injury recovery is often associated with poor functional outcome. The molecular mechanism controlling the per...
  4. Collateral development and spinal motor reorganization after nerve injury and repair.

    American journal of translational research 8(7):2897 (2016) PMID 27508011 PMCID PMC4969427

    Functional recovery is often unsatisfactory after severe extended nerve defects or proximal nerve trunks injuries repaired by traditional repair methods, as the long regeneration distance for the regenerated axons to reinnervate their original target end-organs. The proximal nerve stump can rege...
  5. Modelling Estimates of Norovirus Disease in Patients with Chronic Medical Conditions.

    PLoS ONE 11(7):e0158822 (2016) PMID 27438335 PMCID PMC4954678

    The burden of disease due to norovirus infection has been well described in the general United States population, but studies of norovirus occurrence among persons with chronic medical conditions have been limited mostly to the immunocompromised. We assessed the impact of norovirus gastroenterit...
  6. Incidence of venous thromboembolism and hemorrhage related safety studies of preoperative anticoagulation therapy in hip fracture patients undergoing surgical treatment: a case-control study.

    BMC Musculoskeletal Disorders 17(1):76 (2016) PMID 26873584 PMCID PMC4752756

    Venous thromboembolism is a common postoperative complication following orthopedic surgeries, with morbid and potentially fatal consequences. Perioperative low-molecular-weight heparin (LMWH) therapy can reduce the incidence of venous thromboembolism, but may also increase the risk of bleeding c...
  7. Peripheral nerve mutilation through biodegradable conduit small gap tubulisation: a multicentre randomised trial

    The Lancet 386:S40 (2015)

    Background Although peripheral nerve injury is repaired by ingenious epineurial neurorrhaphy, functional recovery is usually not satisfactory and is hindered by many factors, including the misconnections of sensory and motor nerve fibres, difficulties in target organ reinnerv...
  8. Changes and trends of pre-hospital emergency disease spectrum in Beijing in 2003–12: a retrospective study

    The Lancet 386:S39 (2015)

    Background Pre-hospital emergency call is a crucial indicator of emergency disease spectrum. Since Beijing has changed substantially in economy and population, analysis of the trend of the emergency disease spectrum can greatly contribute to pre-hospital emergency planning. ...
  9. Current state of trauma care in China, tools to predict death and ICU admission after arrival to hospital.

    Injury 46(9):1784 (2015) PMID 26093963

    In China, a nationwide emergency system takes charge of pre-hospital emergency services, and it adopts a proximity principle to send trauma patients to the nearest hospitals. However, many severely injured patients have been sent to low level hospitals with no capability to treat severe trauma. ...
  10. [The challenges faced in the field of trauma care in China].

    Zhonghua wai ke za zhi [Chinese journal of surg... 53(6):401 (2015) PMID 26359050

    With the continuous development of China's urbanization and socio-economic, death and disability caused by trauma has increased prominently, and trauma has become the first cause of death in the people younger than 45 years old. Compared with the treatment of other diseases, China are facing man...
  11. Road traffic injury and rescue system in China.

    The Lancet 385(9978):1622 (2015) PMID 25943819

  12. Early nerve protection with anterior interosseous nerve in modified end-to-side neurorrhaphy repairs high ulnar nerve injury: a hypothesis of a novel surgical technique.

    Artificial Cells, Nanomedicine and Biotechnology 43(2):103 (2015) PMID 24195580

    High ulnar nerve injuries frequently result in poor functional recovery. The prolonged denervation of target muscle largely accounts for the poor functional outcome. There are no approved effective treatments for high ulnar nerve injuries. However, the technique of reverse end-to-side (RETS) off...
  13. Motor function recovery during peripheral nerve multiple regeneration.

    Journal Of Tissue Engineering And Regenerative ... 9(4):415 (2015) PMID 24323657

    Neuronal functional compensation and multiple regenerating axon sprouting occur during peripheral nerve regeneration. Sprouting nerve buds were quantitatively maintained and had matured when multiple injured distal nerves were anastomosed to smaller number of proximal nerve stumps; this has posi...
  14. Radiological characteristics and anatomical risk factors in the evaluation of hallux valgus in chinese adults.

    Chinese Medical Journal 128(1):51 (2015) PMID 25563313 PMCID PMC4837819

    There are no unified theories as to the anatomical changes that occur with hallux valgus, we investigated the radiological characteristics and anatomical risk factors for hallux valgus deformity in Chinese adults. We reviewed 141 patients with hallux valgus (206 feet; 15 males, 126 females; mean...
  15. Healing of cancellous fracture in a novel mouse model.

    American journal of translational research 7(11):2279 (2015) PMID 26807176 PMCID PMC4697708

    Fractures are one of the most prevalent clinical conditions worldwide. Among them, cancellous fracture is a major cause of extremities fractures. Unfortunately, it is largely unknown about how is the healing of cancellous fracture. In the current study, we present a novel cancellous fracture mic...
  16. Specificity of motor axon regeneration: a comparison of recovery following biodegradable conduit small gap tubulization and epineurial neurorrhaphy.

    American journal of translational research 7(1):53 (2015) PMID 25755828 PMCID PMC4346523

    Functional recovery is often unsatisfactory after lesions in the peripheral nervous system despite the strong potential for regeneration and advances in microsurgical techniques. Axonal regeneration in mixed nerve into inappropriate pathways is a major contributing factor to this failure. In thi...
  17. Local administration of IKK small molecule inhibitor may enhance fracture healing in osteoporosis patient.

    International journal of clinical and experimen... 8(1):1411 (2015) PMID 25785147 PMCID PMC4358602

    Osteoporosis is an inflammatory bone disease affecting millions of population worldwide, which often cause increased fracture risks and prolonged fracture healing. Growing evidence suggests that IKK-NF-κB signaling exert inhibitory influence on MSCs osteogenic differentiation and bone formation....
  18. Using suture and locking anatomical bridging plate to fix comminuted mid-shaft clavicle fractures with intramedullary nail assistance in reduction.

    International journal of clinical and experimen... 8(7):11153 (2015) PMID 26379917 PMCID PMC4565300

    During conventional plate fixation of comminuted midshaft fracture of the clavicle, wedge-shaped fragments often need to be fixed with lag screws. A new procedure, which included intramedullary K-wire assistance in reduction, binding fragments by suture, and eventually bridging plate fixation, w...
  19. Local transplantation of osteogenic pre-differentiated autologous adipose-derived mesenchymal stem cells may accelerate non-union fracture healing with limited pro-metastatic potency.

    International journal of clinical and experimen... 8(1):1406 (2015) PMID 25785146 PMCID PMC4358601

    Fracture non-union is a serious complication in orthopedic clinical practice. Mesenchymal stem cells are believed to play a vital role in fracture healing process. Among various origins of mesenchymal stem cell, adipose derived stem cells hold great promise especially in clinical milieu. However...
  20. Efficacy and safety of rivaroxaban versus low-molecular-weight heparin therapy in patients with lower limb fractures.

    Journal of Thrombosis and Thrombolysis 38(3):299 (2014) PMID 24402194

    Thromboprophylaxis with rivaroxaban has proved effective and safe in patients undergoing hip and knee replacement surgery. As it is unclear whether it is also effective and safe in fracture patients, the aim of the present study was to evaluate the efficacy and safety of rivaroxaban in patients ...