A genetically novel, narrow-host-range isolate of cucumber mosaic virus (CMV) from rosemary.
Archives of Virology 161(7):2013 (2016)
An isolate of cucumber mosaic virus (CMV), designated CMV-Rom, was isolated from rosemary (Rosmarinus officinalis) plants in several locations near Avignon, France. Laboratory studies showed that, unlike typical CMV isolates, CMV-Rom has a particularly narrow host range. It could be transmitted ...
Diversity of genetic backgrounds modulating the durability of a major resistance gene. Analysis of a core collection of pepper landraces resistant to Potato virus Y.
Molecular Plant Pathology 17(2):296 (2016)
The evolution of resistance-breaking capacity in pathogen populations has been shown to depend on the plant genetic background surrounding the resistance genes. We evaluated a core collection of pepper (Capsicum annuum) landraces, representing the worldwide genetic diversity, for its ability to ...
Genetic Determinism and Evolutionary Reconstruction of a Host Jump in a Plant Virus.
Molecular Biology and Evolution 33(2):541 (2016)
In spite of their widespread occurrence, only few host jumps by plant viruses have been evidenced and the molecular bases of even fewer have been determined. A combination of three independent approaches, 1) experimental evolution followed by reverse genetics analysis, 2) positive selection anal...
Epidemiological and evolutionary management of plant resistance: optimizing the deployment of cultivar mixtures in time and space in agricultural landscapes.
Evolutionary Applications 8(10):919 (2015)
The management of genes conferring resistance to plant-pathogens should make it possible to control epidemics (epidemiological perspective) and preserve resistance durability (evolutionary perspective). Resistant and susceptible cultivars must be strategically associated according to the princip...
Special issue for the plant resistance sustainability international conference, la colle sur loup, france, 16-19 october 2012.
Infection, Genetics and Evolution 27:445 (2014)
Interaction patterns between potato virus Y and eIF4E-mediated recessive resistance in the Solanaceae.
Journal of Virology 88(17):9799 (2014)
The structural pattern of infectivity matrices, which contains infection data resulting from inoculations of a set of hosts by a set of parasites, is a key parameter for our understanding of biological interactions and their evolution. This pattern determines the evolution of parasite pathogenic...
Narrow bottlenecks affect Pea seedborne mosaic virus populations during vertical seed transmission but not during leaf colonization.
PLoS Pathogens 10(1):e1003833 (2014)
The effective size of populations (Ne) determines whether selection or genetic drift is the predominant force shaping their genetic structure and evolution. Populations having high Ne adapt faster, as selection acts more intensely, than populations having low Ne, where random effects of genetic ...
Potato virus Y: a major crop pathogen that has provided major insights into the evolution of viral pathogenicity.
Molecular Plant Pathology 14(5):439 (2013)
Potato virus Y (PVY) is the type member of the genus Potyvirus in the family Potyviridae. VIRION AND GENOME PROPERTIES: PVY virions have a filamentous, flexuous form, with a length of 730 nm and a diameter of 12 nm. The genomic RNA is single stranded, messenger sense, with a length of 9.7 kb, co...
High prevalence of poleroviruses in field-grown pepper in Turkey and Tunisia.
Archives of Virology 158(4):881 (2013)
Open-field pepper crops were sampled in 2011 in Turkey and Tunisia and surveyed for the major pepper-infecting viruses. As expected, potato virus Y and cucumber mosaic virus (in both countries), and tobacco etch virus (in Turkey only) were quite frequent. However, poleroviruses were the most com...
Farther, slower, stronger: how the plant genetic background protects a major resistance gene from breakdown.
Molecular Plant Pathology 14(2):109 (2013)
Genetic resistance provides efficient control of crop diseases, but is limited by pathogen evolution capacities which often result in resistance breakdown. It has been demonstrated recently, in three different pathosystems, that polygenic resistances combining a major-effect gene and quantitativ...
Durable strategies to deploy plant resistance in agricultural landscapes.
New Phytologist 193(4):1064 (2012)
The deployment of resistant crops often leads to the emergence of resistance-breaking pathogens that suppress the yield benefit provided by the resistance. Here, we theoretically explored how farmers' main leverages (resistant cultivar choice, resistance deployment strategy, landscape planning a...
Modelling the evolutionary dynamics of viruses within their hosts: a case study using high-throughput sequencing.
PLoS Pathogens 8(4):e1002654 (2012)
Uncovering how natural selection and genetic drift shape the evolutionary dynamics of virus populations within their hosts can pave the way to a better understanding of virus emergence. Mathematical models already play a leading role in these studies and are intended to predict future emergences...
Viruses of pepper crops in the Mediterranean basin: a remarkable stasis.
Advances in Virus Research 84:127 (2012)
Compared to other vegetable crops, the major viral constraints affecting pepper crops in the Mediterranean basin have been remarkably stable for the past 20 years. Among these viruses, the most prevalent ones are the seed-transmitted tobamoviruses; the aphid-transmitted Potato virus Y and Tobacc...
Genetic background matters: a plant-virus gene-for-gene interaction is strongly influenced by genetic contexts.
Molecular Plant Pathology 12(9):911 (2011)
Evolutionary processes responsible for parasite adaptation to their hosts determine our capacity to manage sustainably resistant plant crops. Most plant-parasite interactions studied so far correspond to gene-for-gene models in which the nature of the alleles present at a plant resistance locus ...
dN/dS-based methods detect positive selection linked to trade-offs between different fitness traits in the coat protein of potato virus Y.
Molecular Biology and Evolution 28(9):2707 (2011)
The dN/dS ratio between nonsynonymous and synonymous substitution rates has been used extensively to identify codon positions involved in adaptive processes. However, the accuracy of this approach has been questioned, and very few studies have attempted to validate experimentally its predictions...
The helper component proteinase cistron of Potato virus Y induces hypersensitivity and resistance in Potato genotypes carrying dominant resistance genes on chromosome IV.
Molecular Plant-Microbe Interactions 24(7):787 (2011)
The Nc(tbr) and Ny(tbr) genes in Solanum tuberosum determine hypersensitive reactions, characterized by necrotic reactions and restriction of the virus systemic movement, toward isolates belonging to clade C and clade O of Potato virus Y (PVY), respectively. We describe a new resistance from S. ...
Evolution and structure of Tomato spotted wilt virus populations: evidence of extensive reassortment and insights into emergence processes.
Journal of General Virology 92(Pt 4):961 (2011)
Tomato spotted wilt virus (TSWV; genus Tospovirus, family Bunyaviridae) genetic diversity was evaluated by sequencing parts of the three RNA genome segments of 224 isolates, mostly from pepper and tomato crops in southern Europe. Eighty-three per cent of the isolates showed consistent clustering...
Evolutionary time-scale of the begomoviruses: evidence from integrated sequences in the Nicotiana genome.
PLoS ONE 6(5):e19193 (2011)
Despite having single stranded DNA genomes that are replicated by host DNA polymerases, viruses in the family Geminiviridae are apparently evolving as rapidly as some RNA viruses. The observed substitution rates of geminiviruses in the genera Begomovirus and Mastrevirus are so high that the enti...
A point mutation in the polymerase of Potato virus Y confers virulence toward the Pvr4 resistance of pepper and a high competitiveness cost in susceptible cultivar.
Molecular Plant-Microbe Interactions 23(6):823 (2010)
To understand why the Pvr4 resistance of pepper against Potyvirus spp. remained durable in field conditions while virulent Potato virus Y (PVY) variants could be selected in the laboratory, we studied the molecular mechanisms which generated these variants and the consequences on viral fitness. ...
A new lineage sheds light on the evolutionary history of Potato virus Y.
Molecular Plant Pathology 11(1):161 (2010)
Potato virus Y (PVY) is one of the rare plant viruses for which some biological traits (host range and symptomatology) are highly correlated with phylogeny, allowing the reconstruction of the evolutionary history of these traits. In this article, a new lineage of PVY isolates from Chile is descr...