1. A role for FtsA in SPOR-independent localization of the essential Escherichia coli cell division protein FtsN.

    Molecular Microbiology 92(6):1212 (2014) PMID 24750258 PMCID PMC4079119

    FtsN is a bitopic membrane protein and the last essential component to localize to the Escherichia coli cell division machinery, or divisome. The periplasmic SPOR domain of FtsN was previously shown to localize to the divisome in a self-enhancing manner, relying on the essential activity of FtsN...
  2. A role for FtsA in SPOR-independent localization of the essential Escherichia coli cell division protein FtsN.

    Molecular Microbiology 92(6):1212 (2014) PMID 24750258 PMCID PMC4079119

    FtsN is a bitopic membrane protein and the last essential component to localize to the Escherichia coli cell division machinery, or divisome. The periplasmic SPOR domain of FtsN was previously shown to localize to the divisome in a self-enhancing manner, relying on the essential activity of FtsN...
  3. Organization of FtsZ filaments in the bacterial division ring measured from polarized fluorescence microscopy.

    Biophysical Journal 105(9):1976 (2013) PMID 24209842 PMCID PMC3824704

    Cytokinesis in bacteria is accomplished by a ring-shaped cell-division complex (the Z-ring). The primary component of the Z-ring is FtsZ, a filamentous tubulin homolog that serves as a scaffold for the recruitment of other cell-division-related proteins. FtsZ forms filaments and bundles. In the ...
  4. Organization of FtsZ Filaments in the Bacterial Division Ring Measured from Polarized Fluorescence Microscopy

    Biophysical Journal 105(9):1976 (2013)

    Cytokinesis in bacteria is accomplished by a ring-shaped cell-division complex (the Z-ring). The primary component of the Z-ring is FtsZ, a filamentous tubulin homolog that serves as a scaffold for the recruitment of other cell-division-related proteins. FtsZ forms filaments and bundle...
  5. The early divisome protein FtsA interacts directly through its 1c subdomain with the cytoplasmic domain of the late divisome protein FtsN.

    Journal of Bacteriology 194(8):1989 (2012) PMID 22328664 PMCID PMC3318488

    In Escherichia coli, FtsN localizes late to the cell division machinery, only after a number of additional essential proteins are recruited to the early FtsZ-FtsA-ZipA complex. FtsN has a short, positively charged cytoplasmic domain (FtsN(Cyto)), a single transmembrane domain (FtsN(TM)), and a p...
  6. Split decision: a thaumarchaeon encoding both FtsZ and Cdv cell division proteins chooses Cdv for cytokinesis.

    Molecular Microbiology 82(3):535 (2011) PMID 21895799 PMCID PMC3298680

    Cytoskeletal proteins play a pivotal role in cytokinesis in prokaryotes and eukaryotes. Most bacteria and a major branch of the archaea called the Euryarchaeota harbour a tubulin homologue, FtsZ, which assembles into a dynamic polymeric ring structure required for cytokinesis. However, Crenarcha...
  7. Matrilysin expression by human mononuclear phagocytes and its regulation by cytokines and hormones.

    Journal of Immunology 154(12):6484 (1995) PMID 7759883

    Matrilysin is a recently described metalloproteinase with strong catalytic activity against a variety of extracellular matrix substrates including proteoglycans, elastin, laminin, fibronectin, gelatin, and entactin. Production of this metalloproteinase appears to be limited only to a few normal ...
  8. The matrix metalloprotease matrilysin (PUMP) is expressed in developing human mononuclear phagocytes.

    Journal of Biological Chemistry 267(13):9087 (1992) PMID 1374384

    Matrilysin (PUMP, MMP-7) is a member of the metalloprotease gene family, whose constituents are responsible for the remodeling of extracellular matrix. The matrilysin protein is a 28-kDa zymogen possessing catalytic activities against a broad range of extracellular matrix substrates including pr...
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  9. Diminished response of Werner's syndrome fibroblasts to growth factors PDGF and FGF.

    Science 234(4781):1240 (1986) PMID 3022382

    Patients with Werner's syndrome, an autosomal recessive disorder, undergo an accelerated aging process that leads to premature death. Fibroblasts from such patients typically grow poorly in culture. Here it is shown that fibroblasts from a patient with Werner's syndrome have a markedly attenuate...
  10. Environmental pH modulation of collagenase in normal human fibroblast cultures.

    Biochimica et Biophysica Acta 585(3):389 (1979) PMID 39627

    Normal human skin fibroblast cultures have been used to assess the effects of relatively minor changes in environmental pH on collagenase, a major extracellular gene product. Collagenase accumulation in the culture medium, measured both as enzyme activity and immunoreactive material, was 2- to 1...
  11. Environmental pH modulation of collagenase in normal human fibroblast cultures

    Biochimica et Biophysica Acta (BBA) - General S... 585(3):389 (1979)

    Normal human skin fibroblast cultures have been used to assess the effects of relatively minor changes in environmental pH on collagenase, a major extracellular gene product. Collagenase accumulation in the culture medium, measured both as enzyme activity and immunoreactive material, was 2-...
  12. Five cases of pigmentary retinopathy associated with thioridazine administration.

    American Journal of Psychiatry 123(1):97 (1966) PMID 5935198

  13. The effect of Polybrene on blood coagulation. In vitro.

    Journal of Laboratory and Clinical Medicine 58:23 (1961) PMID 13750657

  14. The effect of Polybrene on blood coagulation. In vitro

    Journal of Laboratory and Clinical Medicine 58(1):23 (1961)

    Since Polybrene, a new antiheparin agent, has itself been reported to be an anticoagulant, studies were carried out to determine its in vitro effect on the various stages of blood coagulation. In concentrations comparable to dosages administered clinically, Polybrene prolongs whole blood cl...
  15. The epinephrine-mecholyl test applied to a state hospital population.

    American Journal of Psychiatry 117:154 (1960) PMID 14430104

  16. Acute, diffuse, interstitial fibrosis of the lungs: report of a case.

    Diseases of the chest 37:444 (1960) PMID 14441469

  17. Aortic arch syndrome with report of a case in a geriatric patient.

    Geriatrics 14(8):533 (1959) PMID 13672393

  18. CARDIORESPIRATORY SYNDROME OF EXTREME OBESITY

    The Lancet 273(7076):788 (1959)

  19. Assimilation in the immediate reproduction of visually perceived figures.

    Journal of Experimental Psychology 44(3):151 (1952) PMID 12990756