1. Uninflatable and Notch Control the Targeting of Sara Endosomes during Asymmetric Division

    Current Biology 25(6):817 (2015)

  2. Uninflatable and Notch control the targeting of sara endosomes during asymmetric division.

    Current Biology 24(18):2142 (2014) PMID 25155514

    Cell fate decision during asymmetric division is mediated by the biased partition of cell fate determinants during mitosis [1-6]. In the case of the asymmetric division of the fly sensory organ precursor cells, directed Notch signaling from pIIb to the pIIa daughter endows pIIa with its distinct...
  3. Uninflatable and Notch Control the Targeting of Sara Endosomes during Asymmetric Division

    Current Biology 24(18):2142 (2014)

    Cell fate decision during asymmetric division is mediated by the biased partition of cell fate determinants during mitosis [1–6]. In the case of the asymmetric division of the fly sensory organ precursor cells, directed Notch signaling from pIIb to the pIIa daughter endows pIIa with it...
  4. Uninflatable and Notch control the targeting of Sara endosomes during asymmetric division.

    Current Biology 24(18):2142 (2014) PMID 25155514

    Cell fate decision during asymmetric division is mediated by the biased partition of cell fate determinants during mitosis [1-6]. In the case of the asymmetric division of the fly sensory organ precursor cells, directed Notch signaling from pIIb to the pIIa daughter endows pIIa with its distinct...
  5. Uninflatable and Notch Control the Targeting of Sara Endosomes during Asymmetric Division

    Current Biology (2012)

  6. Characterization of Neurospora crassa α-actinin.

    Current Microbiology 63(1):100 (2011) PMID 21598047

    α-Actinin, an actin-binding protein of the spectrin superfamily, is present in most eukaryotes except plants. It is composed of three domains: N-terminal CH-domains, C-terminal calcium-binding domain (with EF-hand motifs), and a central rod domain. We have cloned and expressed Neurospora crassa ...
  7. Characterization of Neurospora crassa α-actinin.

    Current Microbiology 63(1):100 (2011) PMID 21598047

    α-Actinin, an actin-binding protein of the spectrin superfamily, is present in most eukaryotes except plants. It is composed of three domains: N-terminal CH-domains, C-terminal calcium-binding domain (with EF-hand motifs), and a central rod domain. We have cloned and expressed Neurospora crassa ...
  8. Sumoylation of Drosophila SU(VAR)3-7 is required for its heterochromatic function.

    Nucleic Acids Research 38(13):4254 (2010) PMID 20299342 PMCID PMC2910048

    In Drosophila, SU(VAR)3-7 is an essential heterochromatin component. It is required for proper chromatin condensation, and changing its dose modifies position-effect variegation. Sumoylation is a post-translational modification shown to play a role in diverse biological processes. Here, we demon...
  9. Sumoylation of Drosophila SU(VAR)3-7 is required for its heterochromatic function.

    Nucleic Acids Research 38(13):4254 (2010) PMID 20299342 PMCID PMC2910048

    In Drosophila, SU(VAR)3-7 is an essential heterochromatin component. It is required for proper chromatin condensation, and changing its dose modifies position-effect variegation. Sumoylation is a post-translational modification shown to play a role in diverse biological processes. Here, we demon...
  10. Transcriptional activation by GAGA factor is through its direct interaction with dmTAF3.

    Developmental Biology 317(2):660 (2008) PMID 18367161

    The GAGA factor (GAF), encoded by the Trithorax like gene (Trl) is a multifunctional protein involved in gene activation, Polycomb-dependent repression, chromatin remodeling and is a component of chromatin domain boundaries. Although first isolated as transcriptional activator of the Drosophila ...
  11. Transcriptional activation by GAGA factor is through its direct interaction with dmTAF3

    Developmental Biology 317(2):660 (2008)

    The GAGA factor (GAF), encoded by the Trithorax like gene ( Trl) is a multifunctional protein involved in gene activation, Polycomb-dependent repression, chromatin remodeling and is a component of chromatin domain boundaries. Although first isolated as transcriptional ac...
  12. Transcriptional activation by GAGA factor is through its direct interaction with dmTAF3

    Developmental Biology 317(2):660 (2008) PMID 18367161

    The GAGA factor (GAF), encoded by the Trithorax like gene ( Trl) is a multifunctional protein involved in gene activation, Polycomb-dependent repression, chromatin remodeling and is a component of chromatin domain boundaries. Although first isolated as transcriptional ac...
  13. Transcriptional activation by GAGA factor is through its direct interaction with dmTAF3

    Developmental Biology 317(2):660 (2008) PMID 18367161

    The GAGA factor (GAF), encoded by the Trithorax like gene ( Trl) is a multifunctional protein involved in gene activation, Polycomb-dependent repression, chromatin remodeling and is a component of chromatin domain boundaries. Although first isolated as transcriptional ac...
  14. Drosophila G9a is a nonessential gene.

    Genetics 177(3):1955 (2007) PMID 18039887 PMCID PMC2147950

    Mammalian G9a is a euchromatic histone H3 lysine 9 (H3K9) methyltransferase essential for development. Here, we characterize the Drosophila homolog of G9a, dG9a. We generated a dG9a deletion allele by homologous recombination. Analysis of this allele revealed that, in contrast to recent findings...
  15. Drosophila G9a is a nonessential gene.

    Genetics 177(3):1955 (2007) PMID 18039887 PMCID PMC2147950

    Mammalian G9a is a euchromatic histone H3 lysine 9 (H3K9) methyltransferase essential for development. Here, we characterize the Drosophila homolog of G9a, dG9a. We generated a dG9a deletion allele by homologous recombination. Analysis of this allele revealed that, in contrast to recent findings...
  16. Drosophila SETDB1 is required for chromosome 4 silencing.

    PLoS Genetics 3(5):e76 (2007) PMID 17500594 PMCID PMC1866353

    Histone H3 lysine 9 (H3K9) methylation is associated with gene repression and heterochromatin formation. In Drosophila, SU(VAR)3-9 is responsible for H3K9 methylation mainly at pericentric heterochromatin. However, the histone methyltransferases responsible for H3K9 methylation at euchromatic si...
  17. Drosophila SETDB1 is required for chromosome 4 silencing.

    PLoS Genetics 3(5):e76 (2007) PMID 17500594 PMCID PMC1866353

    Histone H3 lysine 9 (H3K9) methylation is associated with gene repression and heterochromatin formation. In Drosophila, SU(VAR)3-9 is responsible for H3K9 methylation mainly at pericentric heterochromatin. However, the histone methyltransferases responsible for H3K9 methylation at euchromatic si...
  18. Loss of the modifiers of variegation Su(var)3-7 or HP1 impacts male X polytene chromosome morphology and dosage compensation.

    Journal of Cell Science 118(Pt 21):5047 (2005) PMID 16234327

    Loss of Su(var)3-7 or HP1 suppresses the genomic silencing of position-effect variegation, whereas over-expression enhances it. In addition, loss of Su(var)3-7 results in preferential male lethality. In polytene chromosomes deprived of Su(var)3-7, we observe a specific bloating of the male X chr...
  19. Loss of the modifiers of variegation Su(var)3-7 or HP1 impacts male X polytene chromosome morphology and dosage compensation.

    Journal of Cell Science 118(Pt 21):5047 (2005) PMID 16234327

    Loss of Su(var)3-7 or HP1 suppresses the genomic silencing of position-effect variegation, whereas over-expression enhances it. In addition, loss of Su(var)3-7 results in preferential male lethality. In polytene chromosomes deprived of Su(var)3-7, we observe a specific bloating of the male X chr...
  20. Isolation of Su(var)3-7 mutations by homologous recombination in Drosophila melanogaster.

    Genetics 161(3):1125 (2002) PMID 12136016 PMCID PMC1462191

    The Su(var)3-7 gene, a haplo-suppressor and triplo-enhancer of position-effect variegation (PEV), encodes a zinc finger heterochromatin-associated protein. To understand the role of this protein in heterochromatin and genomic silencing, mutations were generated by homologous recombination. The d...