1. Aryl hydrocarbon receptor is necessary to protect fetal human pulmonary microvascular endothelial cells against hyperoxic injury: Mechanistic roles of antioxidant enzymes and RelB.

    Toxicology and Applied Pharmacology 286(2):92 (2015) PMID 25831079 PMCID PMC4458211

    Hyperoxia contributes to the development of bronchopulmonary dysplasia (BPD) in premature infants. Activation of the aryl hydrocarbon receptor (AhR) protects adult and newborn mice against hyperoxic lung injury by mediating increases in the expression of phase I (cytochrome P450 (CYP) 1A) and ph...
  2. Polycyclic aromatic hydrocarbons: from metabolism to lung cancer.

    Toxicological Sciences 145(1):5 (2015) PMID 25911656 PMCID PMC4408964

    Excessive exposure to polycyclic aromatic hydrocarbons (PAHs) often results in lung cancer, a disease with the highest cancer mortality in the United States. After entry into the lung, PAHs induce phase I metabolic enzymes such as cytochrome P450 (CYP) monooxygenases, i.e. CYP1A1/2 and 1B1, and ...
  3. Anthracene/Phenothiazine π-Conjugated Sensitizers for Dye-Sensitized Solar Cells using Redox Mediator in Organic and Water-based Solvents.

    Chemsuschem Chemistry And Sustainability, Energ... 8(1):105 (2015) PMID 25404282

    Metal-free dyes (MD1 to MD5) containing an anthracene/phenothiazine unit in the spacer have been synthesized. The conversion efficiency (7.13 %) of the dye-sensitized solar cell using MD3 as the sensitizer reached approximately 85 % of the N719-based standard cell (8.47 %). The cell efficiency (...
  4. Anthracene/phenothiazine π-conjugated sensitizers for dye-sensitized solar cells using redox mediator in organic and water-based solvents.

    Chemsuschem Chemistry And Sustainability, Energ... 8(1):105 (2015) PMID 25404282

    Metal-free dyes (MD1 to MD5) containing an anthracene/phenothiazine unit in the spacer have been synthesized. The conversion efficiency (7.13 %) of the dye-sensitized solar cell using MD3 as the sensitizer reached approximately 85 % of the N719-based standard cell (8.47 %). The cell efficiency (...
  5. Distinct effects of Disabled-2 on transferrin uptake in different cell types and culture conditions.

    Cell Biology International 38(11):1252 (2014) PMID 24889971

    Iron uptake by the transferrin (Tf)-transferrin receptor (TfR) complex is critical for erythroid differentiation. The mechanisms of TfR trafficking have been examined, but the adaptor proteins involved in this process are not fully elucidated. We have investigated the role of the adaptor protein...
  6. On-line SERS detection of single bacterium using novel SERS nanoprobes and a microfluidic dielectrophoresis device.

    Small 10(22):4700 (2014) PMID 25115777

    The integration of novel surface-enhanced Raman scattering (SERS) nanoprobes and a microfluidic dielectrophoresis (DEP) device is developed for rapid on-line SERS detection of Salmonella enterica serotype Choleraesuis and Neisseria lactamica. The SERS nanoprobes are prepared by immobilization of...
  7. On-line SERS Detection of Single Bacterium Using Novel SERS Nanoprobes and A Microfluidic Dielectrophoresis Device.

    Small 10(22):4700 (2014) PMID 25115777

    The integration of novel surface-enhanced Raman scattering (SERS) nanoprobes and a microfluidic dielectrophoresis (DEP) device is developed for rapid on-line SERS detection of Salmonella enterica serotype Choleraesuis and Neisseria lactamica. The SERS nanoprobes are prepared by immobilization of...
  8. Biosensors: On-line SERS Detection of Single Bacterium Using Novel SERS Nanoprobes and A Microfluidic Dielectrophoresis Device (Small 22/2014).

    Small 10(22):4414 (2014) PMID 25412453

    On-line multiplex SERS detection of pathogenic bacteria is demonstrated at a single-cell level. On page 4700, L.-K. Chau, C.-Y. Yang, and co-workers prepare SERS nanoprobes via immobilization of antibodies on silica-coated, dye-induced aggregate beads of gold nanoparticles (AuNPs). The beads giv...
  9. Magnetic-resonance imaging for kinetic analysis of permeability changes during focused ultrasound-induced blood–brain barrier opening and brain drug delivery

    Journal of Controlled Release 192:1 (2014)

    Focused ultrasound (FUS) with the presence of microbubbles has been shown to induce transient and local opening of the blood–brain barrier (BBB) for the delivery of therapeutic molecules which normally cannot penetrate into the brain. The success of FUS brain–drug delivery relies on it...
  10. Magnetic-resonance imaging for kinetic analysis of permeability changes during focused ultrasound-induced blood-brain barrier opening and brain drug delivery.

    Journal of Controlled Release 192:1 (2014) PMID 24969355

    Focused ultrasound (FUS) with the presence of microbubbles has been shown to induce transient and local opening of the blood-brain barrier (BBB) for the delivery of therapeutic molecules which normally cannot penetrate into the brain. The success of FUS brain-drug delivery relies on its integrat...
  11. Magnetic-resonance imaging for kinetic analysis of permeability changes during focused ultrasound-induced blood–brain barrier opening and brain drug delivery

    Journal of Controlled Release 192:1 (2014)

    Focused ultrasound (FUS) with the presence of microbubbles has been shown to induce transient and local opening of the blood–brain barrier (BBB) for the delivery of therapeutic molecules which normally cannot penetrate into the brain. The success of FUS brain–drug delivery relies on it...
  12. Magnetic-resonance imaging for kinetic analysis of permeability changes during focused ultrasound-induced blood–brain barrier opening and brain drug delivery

    Journal of Controlled Release 192:1 (2014)

    Focused ultrasound (FUS) with the presence of microbubbles has been shown to induce transient and local opening of the blood–brain barrier (BBB) for the delivery of therapeutic molecules which normally cannot penetrate into the brain. The success of FUS brain–drug delivery relies on it...
  13. Differential concentration-specific effects of caffeine on cell viability, oxidative stress, and cell cycle in pulmonary oxygen toxicity in vitro.

    Biochemical and Biophysical Research Communicat... 450(4):1345 (2014) PMID 24997337 PMCID PMC4216694

    Caffeine is used to prevent bronchopulmonary dysplasia (BPD) in premature neonates. Hyperoxia contributes to the development of BPD, inhibits cell proliferation and decreases cell survival. The mechanisms responsible for the protective effect of caffeine in pulmonary oxygen toxicity remain large...
  14. Differential concentration-specific effects of caffeine on cell viability, oxidative stress, and cell cycle in pulmonary oxygen toxicity in vitro.

    Biochemical and Biophysical Research Communicat... 450(4):1345 (2014) PMID 24997337 PMCID PMC4216694

    Caffeine is used to prevent bronchopulmonary dysplasia (BPD) in premature neonates. Hyperoxia contributes to the development of BPD, inhibits cell proliferation and decreases cell survival. The mechanisms responsible for the protective effect of caffeine in pulmonary oxygen toxicity remain large...
  15. Phenothiazinedioxide-conjugated sensitizers and a dual-TEMPO/iodide redox mediator for dye-sensitized solar cells.

    Chemsuschem Chemistry And Sustainability, Energ... 7(8):2221 (2014) PMID 25044488

    Metal-free dyes containing a phenothiazinedioxide entity in the spacer were synthesized. The best conversion efficiency (7.47%) of the dye-sensitized solar cell (DSSC) by using new sensitizers with chenodeoxycholic acid as a co-adsorbent and the I(-) /I3 (-) electrolyte reached over 90% of that ...
  16. Lupus mesenteric vasculitis with GI and genitourinary tract involvement.

    Clinical Gastroenterology and Hepatology 12(8):e69 (2014) PMID 24393805

  17. Application of an ultrasound-guided low-approach insertion technique in three types of totally implantable access port.

    Journal of the Chinese Medical Association 77(5):246 (2014) PMID 24726676

    Totally implantable access ports (TIAPs) are alternatives to central venous catheters for patients requiring chemotherapy. Since January 2003, we have used a central approach two-point incision technique to insert TIAPs. Following advances in ultrasound technique and clinical experience for tunn...
  18. Design and experimental evaluation of a 256-channel dual-frequency ultrasound phased-array system for transcranial blood-brain barrier opening and brain drug delivery.

    Biomedical Engineering, IEEE Transactions on 61(4):1350 (2014) PMID 24658258

    Focused ultrasound (FUS) in the presence of microbubbles can bring about transcranial and local opening of the blood-brain barrier (BBB) for potential noninvasive delivery of drugs to the brain. A phased-array ultrasound system is essential for FUS-BBB opening to enable electronic steering and c...
  19. [Reducing the pain of intravenous injections in preschool children].

    Hu li za zhi The journal of nursing 61(2 Suppl):S68 (2014) PMID 24677010

    Peripheral intravenous catheter insertion is a significant source of stress for preschoolers during hospitalization. An average of about 85% of pediatric patients at our general pediatric unit are preschoolers. An average 71% of these exhibit severe pain-related behavior during intravenous inser...
  20. One-time ray-tracing optimization method and its application to the design of an illuminator for a tube photo-bioreactor.

    Optics Express 22(5):5357 (2014) PMID 24663876

    This study details a one-time ray-tracing optimization method for the optimization of LED illumination systems [S.-C. Chu and H.-L. Yang, "One-time ray-tracing method for the optimization of illumination system," in Proceedings of International Conference on Optics in Precision Engineering and N...
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