Advanced search×
  1. Development of An ICR Mouse Bioassay for Toxicity Evaluation in Neurotoxic Poisoning Toxins-Contaminated Shellfish

    Biomedical and Environmental Sciences 26(5):346 (2013) PMID 23611128

    Objective To develop an ICR (female) mouse bioassay (MBA) for toxicity confirmation and evaluation of neurotoxins (brevetoxins)-contaminated shellfish.
  2. Development of an ICR mouse bioassay for toxicity evaluation in neurotoxic poisoning toxins-contaminated shellfish.

    Biomedical and Environmental Sciences 26(5):346 (2013) PMID 23611128

    To develop an ICR (female) mouse bioassay (MBA) for toxicity confirmation and evaluation of neurotoxins (brevetoxins)-contaminated shellfish. Brevetoxins (BTX-B) as a causative agent of neurotoxic shellfish poisoning (NSP) under different shellfish matrices were intraperitoneally injected at dif...
  3. Developing a predictive tool for post-operative delirium in orthopaedic settings in Hong Kong

    International Journal of Orthopaedic and Trauma... 16(3):147 (2012)

    Aims A prospective study was conducted to develop a Common Risk-factor Assessment Predictive Tool (CAP) for identifying factors associated with post-operative delirium (POD) in orthopaedic surgery. A high, moderate and low risk score system was developed. The incidence rate o...
  4. Solid-phase extraction clean-up of ciguatoxin-contaminated coral fish extracts for use in the mouse bioassay.

    Food Additives & Contaminants: Part A - Chemist... 26(2):236 (2009) PMID 19680895

    Florisil solid-phase extraction (SPE) cartridges were used for purifying ciguatoxin (CTX)-contaminated coral fish extracts, with the aim of removing extracted lipid but retaining optimal level of CTXs in the purified fractions. The CTX-containing fraction (target fraction) in fish ether extract ...
  5. Effects of dimethyl sulphoxide against liver injury caused by carbon tetrachloride in rats.

    Toxicology Mechanisms and Methods 14(3):167 (2004) PMID 20021143

    A single oral dose of 1.25 ml kg(-1) of carbon tetrachloride (CCl(4)) was sufficient to induce significantly elevated levels of serum glutamic pyruvic transaminase (SGPT) and serum glutamic oxaloacetic transaminase (SGOT) together with signs of acute centrilobular necrosis and fatty accumulation...
  6. Protective effects of N-acetylcysteine against carbon tetrachloride- and trichloroethylene-induced poisoning in rats.

    Environmental Toxicology and Pharmacology 14(3):109 (2003) PMID 21782669

    This research investigates the protective effect of N-acetylcysteine (NAC) against carbon tetrachloride (CCl(4))- and trichloroethylene (TCE)-induced hepatotoxicity in rats. A single dose of 1.25 ml/kg of 20% CCl(4) in corn oil, administered orally, or 20% TCE, administered intraperitoneally, pr...
  7. Protective effects ofN-acetylcysteine against carbon tetrachloride- and trichloroethylene-induced poisoning in rats

    Environmental Toxicology and Pharmacology 14(3):109 (2003) PMID 21782669

    This research investigates the protective effect of N-acetylcysteine (NAC) against carbon tetrachloride (CCl 4)- and trichloroethylene (TCE)-induced hepatotoxicity in rats. A single dose of 1.25 ml/kg of 20% CCl 4 in corn oil, administered orally, or 20% TCE, administered...