1. Ciguatera fish poisoning in Hong Kong--a 10-year perspective on the class of ciguatoxins.

    Toxicon 86:96 (2014) PMID 24878373

    The present study used liquid chromatography-tandem mass spectrometry (LC-MS/MS) to investigate retrospectively ciguatoxin (CTX)-positive samples as determined by mouse bioassay (MBA) in the past 10 years in Hong Kong. The results showed that Pacific CTXs (P-CTX-1, -2 and -3) were the most commo...
  2. Ciguatera fish poisoning in Hong Kong--a 10-year perspective on the class of ciguatoxins.

    Toxicon 86:96 (2014) PMID 24878373

    The present study used liquid chromatography-tandem mass spectrometry (LC-MS/MS) to investigate retrospectively ciguatoxin (CTX)-positive samples as determined by mouse bioassay (MBA) in the past 10 years in Hong Kong. The results showed that Pacific CTXs (P-CTX-1, -2 and -3) were the most commo...
  3. Ciguatera fish poisoning in Hong Kong–A 10-year perspective on the class of ciguatoxins

    Toxicon 86:96 (2014)

    The present study used liquid chromatography-tandem mass spectrometry (LC-MS/MS) to investigate retrospectively ciguatoxin (CTX)-positive samples as determined by mouse bioassay (MBA) in the past 10 years in Hong Kong. The results showed that Pacific CTXs (P-CTX-1, -2 and -3) were the ...
  4. Development of An ICR Mouse Bioassay for Toxicity Evaluation in Neurotoxic Poisoning Toxins-Contaminated Shellfish

    Biomedical and Environmental Sciences 26(5):346 (2013) PMID 23611128

    Objective To develop an ICR (female) mouse bioassay (MBA) for toxicity confirmation and evaluation of neurotoxins (brevetoxins)-contaminated shellfish.
  5. Development of An ICR Mouse Bioassay for Toxicity Evaluation in Neurotoxic Poisoning Toxins-Contaminated Shellfish

    Biomedical and Environmental Sciences 26(5):346 (2013)

    Objective To develop an ICR (female) mouse bioassay (MBA) for toxicity confirmation and evaluation of neurotoxins (brevetoxins)-contaminated shellfish.
  6. Development of an ICR mouse bioassay for toxicity evaluation in neurotoxic poisoning toxins-contaminated shellfish.

    Biomedical and Environmental Sciences 26(5):346 (2013) PMID 23611128

    To develop an ICR (female) mouse bioassay (MBA) for toxicity confirmation and evaluation of neurotoxins (brevetoxins)-contaminated shellfish. Brevetoxins (BTX-B) as a causative agent of neurotoxic shellfish poisoning (NSP) under different shellfish matrices were intraperitoneally injected at dif...
  7. Development of an ICR mouse bioassay for toxicity evaluation in neurotoxic poisoning toxins-contaminated shellfish.

    Biomedical and Environmental Sciences 26(5):346 (2013) PMID 23611128

    To develop an ICR (female) mouse bioassay (MBA) for toxicity confirmation and evaluation of neurotoxins (brevetoxins)-contaminated shellfish. Brevetoxins (BTX-B) as a causative agent of neurotoxic shellfish poisoning (NSP) under different shellfish matrices were intraperitoneally injected at dif...
  8. Developing a predictive tool for post-operative delirium in orthopaedic settings in Hong Kong

    International Journal of Orthopaedic and Trauma... 16(3):147 (2012)

    Aims A prospective study was conducted to develop a Common Risk-factor Assessment Predictive Tool (CAP) for identifying factors associated with post-operative delirium (POD) in orthopaedic surgery. A high, moderate and low risk score system was developed. The incidence rate o...
  9. Developing a predictive tool for post-operative delirium in orthopaedic settings in Hong Kong

    International Journal of Orthopaedic and Trauma... 16(3):147 (2012)

    Aims A prospective study was conducted to develop a Common Risk-factor Assessment Predictive Tool (CAP) for identifying factors associated with post-operative delirium (POD) in orthopaedic surgery. A high, moderate and low risk score system was developed. The incidence rate o...
  10. Cluster analysis of toxins profile pattern as a tool for tracing shellfish contaminated with PSP-toxins.

    Environmental Research 111(8):1083 (2011) PMID 21777914

    Paralytic shellfish poisoning (PSP) is one of the most lethal biotoxin-induced diseases worldwide, which may pose serious public health threat and potential devastating economic damage on fisheries industry in the affected region(s). To prevent the importation of PSP contaminated shellfish to a ...
  11. Cluster analysis of toxins profile pattern as a tool for tracing shellfish contaminated with PSP-toxins

    Environmental Research 111(8):1083 (2011)

    Paralytic shellfish poisoning (PSP) is one of the most lethal biotoxin-induced diseases worldwide, which may pose serious public health threat and potential devastating economic damage on fisheries industry in the affected region(s). To prevent the importation of PSP contaminated shellfish ...
  12. Operational application of a rapid antibody-based detection assay for first line screening of paralytic shellfish toxins in shellfish

    Harmful Algae 9(6):636 (2010)

    Paralytic shellfish poisoning toxins (PSP-toxins) are potent neurotoxins associated with marine dinoflagellates and may accumulate in filter-feeding shellfish to cause food intoxication in human. Monitoring programs for PSP in shellfish rely heavily on the use of traditional mouse bioassay ...
  13. Solid-phase extraction clean-up of ciguatoxin-contaminated coral fish extracts for use in the mouse bioassay.

    Food Additives & Contaminants: Part A - Chemist... 26(2):236 (2009) PMID 19680895

    Florisil solid-phase extraction (SPE) cartridges were used for purifying ciguatoxin (CTX)-contaminated coral fish extracts, with the aim of removing extracted lipid but retaining optimal level of CTXs in the purified fractions. The CTX-containing fraction (target fraction) in fish ether extract ...
  14. Solid-phase extraction clean-up of ciguatoxin-contaminated coral fish extracts for use in the mouse bioassay.

    Food Additives & Contaminants: Part A - Chemist... 26(2):236 (2009) PMID 19680895

    Florisil solid-phase extraction (SPE) cartridges were used for purifying ciguatoxin (CTX)-contaminated coral fish extracts, with the aim of removing extracted lipid but retaining optimal level of CTXs in the purified fractions. The CTX-containing fraction (target fraction) in fish ether extract ...
  15. Effect of steam cooking on distribution of paralytic shellfish toxins in different tissue compartments of scallopsPatinopecten yessoensis

    Food Chemistry 114(1):72 (2009)

    This study investigated the effect of steam cooking on distribution of paralytic shellfish poisoning toxins (PSP-toxins) in scallops Patinopecten yessoensis. Toxins analysis by high-performance liquid chromatography showed that most of the PSP-toxins (>70%) were accumulated in viscer...
  16. Features of ciguatera fish poisoning cases in Hong Kong 2004-2007.

    Biomedical and Environmental Sciences 21(6):521 (2008) PMID 19263809

    To review the clinical features and laboratory investigations of ciguatera patients in Hong Kong between 2004 and 2007 in order to show the timely sampling of implicated fish from ciguatera victims and application of validated mouse bioassay for confirming suspected clinical cases of ciguatera. ...
  17. Features of Ciguatera Fish Poisoning Cases in Hong Kong 2004-2007

    Biomedical and Environmental Sciences 21(6):521 (2008)

    Objective To review the clinical features and laboratory investigations of ciguatera patients in Hong Kong between 2004 and 2007 in order to show the timely sampling of implicated fish from ciguatera victims and application of validated mouse bioassay for confirming suspected clinical ...
  18. S0041-0101(06)00217-0

    Toxicon 48(4):470 (2006)

  19. Study of an outbreak of ciguatera fish poisoning in Hong Kong.

    Toxicon 46(5):563 (2005) PMID 16085209

    Ciguatera fish poisoning (CFP) has been a significant and increasing public health problem in Hong Kong since 1980s. With growing demand for imported live coral fishes, the number of people who suffered from this disease has also been increasing. An outbreak of CFP in 2004 was the second most pr...
  20. Study of an outbreak of ciguatera fish poisoning in Hong Kong

    Toxicon 46(5):563 (2005)

    Ciguatera fish poisoning (CFP) has been a significant and increasing public health problem in Hong Kong since 1980s. With growing demand for imported live coral fishes, the number of people who suffered from this disease has also been increasing. An outbreak of CFP in 2004 was the second mo...