Unexpected red blood cell antibody distributions in Chinese people by a systematic literature review.
Transfusion 56(4):975 (2016)
Unexpected antibodies are frequently associated with hemolytic disease of the fetus and newborn (HDFN) and hemolytic transfusion reactions (HTRs), and screening for those unexpected antibodies is critical for the safety and effectiveness of transfusion. Different populations differ in the preval...
Cardioprotective Effects of Combined Therapy with Hyperbaric Oxygen and Diltiazem Pretreatment on Myocardial Ischemia-Reperfusion Injury in Rats.
Cellular Physiology and Biochemistry 38(5):2015 (2016)
In this study, we examined whether the combination of hyperbaric oxygen (HBO) and diltiazem therapy provided a cardioprotective effect on myocardial ischemia-reperfusion injury (MIRI) rat model.
Sixty healthy Sprague-Dawley rats were randomly divided into sham, IR, diltiazem (5 mg/kg), HBO (0.25...
Toxicological evaluation of Yulangsan polysaccharide in Wistar rats: A 26-week oral gavage study.
Environmental Toxicology and Pharmacology 41:1 (2016)
Although numerous studies have proven the medicinal values of Yulangsan polysaccharide (YLSP), the toxicity of this active ingredient is unknown. In the acute toxicity study, a single oral administration of 24 g/kg YLSP caused neither toxicological symptoms nor mortality, and the LD50 was estima...
Fluid administration and morbidity in transhiatal esophagectomy.
Journal of Surgical Research 200(1):91 (2016)
Esophagectomy is associated with significant morbidity. Optimizing perioperative fluid administration is one potential strategy to mitigate morbidity. We sought to investigate the relationship of intraoperative fluid (IOF) administration to outcomes in patients undergoing transhiatal esophagecto...
Neuroprotection by Polynitrogen Manganese Complexes: Regulation of Reactive Oxygen Species-Related Pathways.
Scientific reports 6:20853 (2016)
Cell death in the central nervous system causes neurologic diseases, in which reactive oxygen species (ROS) play a critical role by either inducing cellular oxidative stress or by increasing the cell tolerance against insult. Neurologic diseases may potentially be treated by regulating ROS level...
Short-Course Hypofractionated Radiation Therapy With Boost in Women With Stages 0 to IIIa Breast Cancer: A Phase 2 Trial.
International Journal of Radiation Oncology*Bio... 94(1):118 (2016)
Conventionally fractionated whole-breast irradiation (WBI) with a boost takes approximately 6 to 7 weeks. We evaluated a short course of hypofractionated (HF), accelerated WBI in which therapy was completed in 3 weeks inclusive of a sequential boost.
We delivered a whole-breast dose of 36.63 Gy ...
Neuroprotective effect of combined therapy with hyperbaric oxygen and madopar on 6-hydroxydopamine-induced Parkinson's disease in rats.
Neuroscience Letters 600:220 (2015)
Parkinson's disease (PD) is a common movement disorder in the elderly. In the present study, we examined whether the combination of hyperbaric oxygen (HBO) and madopar therapy provided a neuroprotective effect on dopaminergic neurons in the substantia nigra using a rat model of PD. Rotational as...
Yulangsan polysaccharide improves redox homeostasis and immune impairment in D-galactose-induced mimetic aging.
Food & Function 6(5):1712 (2015)
Yulangsan polysaccharide (YLSP) is a traditional Chinese medicine used in long-term treatment as a modulator of brain dysfunction and immunity. In this study, we evaluated the protective effect of YLSP against D-galactose-induced impairment of oxidative stress and the immune system and evaluated...
Outcomes of microwave ablation for colorectal cancer liver metastases: a single center experience.
Journal of Surgical Oncology 111(4):410 (2015)
Surgical management of colorectal cancer liver metastases continues to evolve to optimize oncologic outcomes while maximizing parenchymal preservation. Long-term data after intraoperative microwave ablation are limited. This study investigates outcomes and patterns of recurrence in patients who ...
Palladium(II)-catalyzed sequential C-H arylation/aerobic oxidative C-H amination: one-pot synthesis of benzimidazole-fused phenanthridines from 2-arylbenzimidazoles and aryl halides.
Journal of Organic Chemistry 80(5):2827 (2015)
Starting from 2-arylbenzimidazoles and aryl halides, an efficient palladium-based catalytic method for the synthesis of benzimidazole-fused phenanthridines has been developed. This reaction sequence comprises intermolecular C-H arylation and intramolecular aerobic oxidative C-H amination, involv...
DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions.
Nucleic Acids Research 43(2):1268 (2015)
FOXP3 is a lineage-specific transcription factor that is required for regulatory T cell development and function. In this study, we determined the crystal structure of the FOXP3 forkhead domain bound to DNA. The structure reveals that FOXP3 can form a stable domain-swapped dimer to bridge DNA in...
Multiplex fluorescence quantitative polymerase chain reaction for simultaneous detection of hepatitis B virus, hepatitis C virus and human immunodeficiency virus.
Clinical laboratory 61(1-2):53 (2015)
To construct a multiplex fluorescence quantitative polymerase chain reaction (MFQ-PCR) system to simultaneously detect hepatitis B virus (HBV) DNA, hepatitis C virus (HCV) cDNA, and human immunodeficiency virus (HIV) cDNA to reduce the false positive and false negative results, therefore increas...
Association between the European GWAS-identified susceptibility locus at chromosome 4p16 and the risk of atrial septal defect: a case-control study in Southwest China and a meta-analysis.
PLoS ONE 10(4):e0123959 (2015)
Atrial septal defect (ASD) is the third most frequent type of congenital heart anomaly, featuring shunting of blood between the two atria. Gene-environment interaction remains to be an acknowledged cause for ASD occurrence. A recent European genome-wide association study (GWAS) of congenital hea...
Protective immunity against Schistosoma japonicum infection can be provided by IgG antibodies towards periodate-sensitive or periodate-resistant glycans.
Parasites & Vectors 8(1):234 (2015)
It has been well accepted that glycans present in schistosomes are highly antigenic. However, it is not clear what kind of worm glycans can affect the infected host to mount IgG responses and whether mounted anti-glycan IgG responses are protective.
The contribution of antigenicity by glycans wa...
Does nodule size predict compressive symptoms in patients with thyroid nodules?
Gland surgery 3(4):232 (2014)
Thyromegaly and thyroid nodules are known to cause compressive symptoms, but the exact relationship between nodule size and development of compressive symptoms is unclear. We sought to determine whether compressive symptoms are directly related to nodule size.
A retrospective analysis of 99 pati...
Is preoperative fibrinogen really not associated with blood transfusion?
Annals of Thoracic Surgery 98(3):1142 (2014)
Carbonic anhydrase 4 and crystallin α-B immunoreactivity may distinguish benign from malignant thyroid nodules in patients with indeterminate thyroid cytology.
Journal of Surgical Research 190(2):565 (2014)
Thyroid nodules are present in 19%-67% of the population and carry a 5%-10% risk of malignancy. Unfortunately, fine-needle aspiration biopsies are indeterminate in 20%-30% of patients, often necessitating thyroid surgery for diagnosis. Numerous DNA microarray studies including a recently commerc...
Association between the ABO blood group and risk of common cancers.
Journal Of Evidence Based Medicine 7(2):79 (2014)
To investigate the association between five common cancers in western China population and ABO blood group.
Using the data from West China Hospital, we retrospectively reviewed 5012 patients with five common cancers. Blood groups were obtained from medical records. The control group was represen...
Modular synthesis of benzimidazole-fused phenanthridines from 2-arylbenzimidazoles and o-dibromoarenes by a palladium-catalyzed cascade process.
Organic Letters 16(7):1872 (2014)
An efficient palladium-catalyzed route for the synthesis of benzimidazole-fused phenanthridines from o-dibromoarenes and 2-arylbenzimidazoles is described. The sequentially accomplished reaction comprises intermolecular C-H arylation of 2-arylbenzimidazoles followed by an intramolecular N-arylat...
The effect of 17-methoxyl-7-hydroxy-benzene-furanchalcone on NF-κB and the inflammatory response during myocardial ischemia reperfusion injury in rats.
Journal of Cardiovascular Pharmacology 63(1):68 (2014)
The aim of this study was to investigate the effect of 17-methoxyl-7-hydroxy-benzene-furanchalcone (MHBFC) on nuclear factor-kappa-binding (NF-κB) and the inflammatory response in rats with myocardial ischemia reperfusion injury (MI/RI). Sprague-Dawley rats were randomly divided into 7 groups, a...