1. Working memory training triggers delayed chromatin remodeling in the mouse corticostriatothalamic circuit

    Progress in Neuro-Psychopharmacology and Biolog... 60:93 (2015)

    Working memory is a cognitive function serving goal-oriented behavior. In the last decade, working memory training has been shown to improve performance and its efficacy for the treatment of several neuropsychiatric disorders has begun to be examined. Neuroimaging studies have contribu...
  2. Hybrid nanosystems based on natural polymers as protein carriers for respiratory delivery: Stability and toxicological evaluation

    Carbohydrate Polymers 123:369 (2015)

    • CS/CRG/TPP nanoparticles exhibit a biocompatible profile in respiratory epithelial cells. • The nanoparticles are stable in presence of lysozyme. ...
  3. Hybrid nanosystems based on natural polymers as protein carriers for respiratory delivery: Stability and toxicological evaluation

    Carbohydrate Polymers 123:369 (2015)

    • CS/CRG/TPP nanoparticles exhibit a biocompatible profile in respiratory epithelial cells. • The nanoparticles are stable in presence of lysozyme. ...
  4. Hybrid nanosystems based on natural polymers as protein carriers for respiratory delivery: Stability and toxicological evaluation

    Carbohydrate Polymers 123:369 (2015)

    • CS/CRG/TPP nanoparticles exhibit a biocompatible profile in respiratory epithelial cells. • The nanoparticles are stable in presence of lysozyme. ...
  5. Nutritional contents of advanced breeding clones of Solanum tuberosum group Phureja

    LWT - Food Science and Technology 62(1):76 (2015)

    Nutritional contents of seven advanced breeding clones (AC) of potato (Solanum tuberosum group Phureja) and two commercial cultivars, Criolla Colombia and Criolla Galeras, of S. tuberosum group Phureja as control were evaluated. Fat, protein, ash, dietary fibre, and mineral contents we...
  6. Production of bioactive peptide hydrolysates from deer, sheep and pig plasma using plant and fungal protease preparations.

    Food Chemistry 176:54 (2015) PMID 25624206

    Plasma separated from deer, sheep and pig blood, obtained from abattoirs, was hydrolysed using protease preparations from plant (papain and bromelain) and fungal (FP400 and FPII) sources. Antioxidant and antimicrobial activities of the peptide hydrolysates obtained after 1, 2, 4 and 24h of hydro...
  7. Aromatic evolution of wine packed in virgin and recycled PET bottles.

    Food Chemistry 176:376 (2015) PMID 25624246

    The evolution of the aromatic profile of a rosé wine packed in glass, virgin and recycled PET bottles was studied. Wine stored in PET and glass bottles was clearly differentiated after 5months of storage but only by a limited number of compounds. More pronounced decrease of oxygen sensitive comp...
  8. Simulation of chaotic electrokinetic transport: Performance of commercial software versus custom-built direct numerical simulation codes

    Journal of Colloid and Interface Science 446:67 (2015)

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  9. Simulation of chaotic electrokinetic transport: Performance of commercial software versus custom-built direct numerical simulation codes.

    Journal of Colloid and Interface Science 446:67 (2015) PMID 25660706

    Many microfluidic and electrochemical applications involve chaotic transport phenomena that arise due to instabilities stemming from coupling of hydrodynamics with ion transport and electrostatic forces. Recent investigations have revealed the contribution of a wide range of spatio-temporal scal...
  10. Simulation of chaotic electrokinetic transport: Performance of commercial software versus custom-built direct numerical simulation codes

    Journal of Colloid and Interface Science 446:67 (2015)

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  11. Sensitivity to anti-Fas is independent of increased cathepsin D activity and adrenodoxin reductase expression occurring in NOS-3 overexpressing HepG2 cells

    Biochimica et Biophysica Acta (BBA) - Molecular... 1853(5):1182 (2015)

    Stable overexpression of endothelial nitric oxide synthase (NOS-3) in HepG2 cells (4TO-NOS) leads to increased nitro-oxidative stress and upregulation of the cell death mediators p53 and Fas. Thus, NOS-3 overexpression has been suggested as a useful antiproliferative mechanism in hepat...
  12. Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice

    Biochimica et Biophysica Acta (BBA) - Molecular... 1851(5):566 (2015)

    Caloric restriction and intermittent fasting are known to improve glucose homeostasis and insulin resistance in several species including humans. The aim of this study was to unravel potential mechanisms by which these interventions improve insulin sensitivity and protect from type 2 d...
  13. The poro-viscoelastic properties of trabecular bone: a micro computed tomography-based finite element study

    Journal of the Mechanical Behavior of Biomedica... 44:1 (2015)

    Bone is a porous structure with a solid phase that contains hydroxyapatite and collagen. Due to its composition, bone is often represented either as a poroelastic or as a viscoelastic material; however, the poro-viscoelastic formulation that allows integrating the effect of both the fl...
  14. Composite scaffolds for controlled drug release: Role of the polyurethane nanoparticles on the physical properties and cell behaviour

    Journal of the Mechanical Behavior of Biomedica... 44:53 (2015)

    Localised delivery of appropriate biomolecule/drug(s) can be suitable to prevent postoperative infections and inflammation after scaffold implantation in vivo. In this study composite shell scaffolds, based on an internally produced bioactive glass and a commercial hydroxyapatite, were...
  15. A comparison of methods for in vivo assessment of cortical porosity in the human appendicular skeleton

    Bone 73:167 (2015)

    The recent advent of high-resolution peripheral quantitative computed tomography (HR-pQCT) provides new opportunities to measure in vivo human bone microarchitecture. Increasingly, cortical porosity (CtPo) is of particular interest due to its relationship with bone quality and turnover...
  16. Increased hip fracture and mortality in chronic kidney disease individuals: The importance of competing risks

    Bone 73:154 (2015)

    Background Many studies have shown a correlation between chronic kidney disease (CKD) and fracture. However, increased mortality in CKD patients is a competing risk scenario not accounted for in previous studies. Our aim was to investigate the true impact of CKD on hip fractu...
  17. Getting it right for children: improving tuberculosis treatment access and new treatment options.

    Expert Review of Anti-infective Therapy 13(4):451 (2015) PMID 25739933

    Children were often the forgotten victims of the global tuberculosis (TB) epidemic, neglected by traditional TB services as well as maternal and child health initiatives. Luckily this is changing with a greater focus on children and the issues regarding their optimal management. A common misconc...
  18. Composite scaffolds for controlled drug release: Role of the polyurethane nanoparticles on the physical properties and cell behaviour

    Journal of the Mechanical Behavior of Biomedica... 44:53 (2015)

    Localised delivery of appropriate biomolecule/drug(s) can be suitable to prevent postoperative infections and inflammation after scaffold implantation in vivo. In this study composite shell scaffolds, based on an internally produced bioactive glass and a commercial hydroxyapatite, were...
  19. Physiological characteristics of open ocean and coastal phytoplankton communities of Western Antarctic Peninsula and Drake Passage waters

    Deep Sea Research Part I: Oceanographic Researc... 98:115 (2015)

    Photophysiological processes as well as uptake characteristics of iron and inorganic carbon were studied in inshore phytoplankton assemblages of the Western Antarctic Peninsula (WAP) and offshore assemblages of the Drake Passage. Chlorophyll a concentrations and primary productivity de...
  20. A behavioral model of collective action in artisanal and small-scale gold mining

    Ecological Economics 112:98 (2015)

    There is a rising global concern about mercury use in small-scale gold mining because of its harmful effects on ecosystems and human health. Associative entrepreneurship has been promoted as a way of accessing alternative techniques to address this concern. By associative entrepreneurs...