1. Gene expression profiling in necrotizing enterocolitis reveals pathways common to those reported in Crohn's disease.

    BMC Medical Genomics 9(1):6 (2016) PMID 26801768 PMCID PMC4722613

    Necrotizing enterocolitis (NEC) is the most frequent life-threatening gastrointestinal disease experienced by premature infants in neonatal intensive care units. The challenge for neonatologists is to detect early clinical manifestations of NEC. One strategy would be to identify specific markers...
  2. Mo1685 Opposite NOS2-Mediated Roles for Epidermal Growth Factor and Indomethacin in Immature Human Intestinal Inflammation

    Gastroenterology 146(5):S (2014)

  3. Malnutrition in hospitalized children: prevalence, impact, and management.

    Canadian Journal of Dietetic Practice and Research 75(1):29 (2014) PMID 24606957

    Malnutrition in hospitalized children has been reported since the late 1970s. The prevalence of acute and chronic malnutrition was examined in hospitalized patients in a general pediatric unit, and the impact and management of malnutrition were assessed. The nutritional risk score (NRS) and nutr...
  4. Sa2011 Adverse Metabolic Effects of Indomethacin on the Immature Human Intestine

    Gastroenterology 144(5):S (2013)

  5. Deleterious effects of indomethacin in the mid-gestation human intestine.

    Genomics 101(3):171 (2013) PMID 23261704

    The use of the anti-inflammatory drug indomethacin (INDO) in preterm infants has been associated with an increased risk of developing enteropathies. In this study, we have investigated the direct impact of INDO on the human mid-gestation intestinal transcriptome using serum-free organ culture. A...
  6. Burden of rotavirus disease: A population-based study in Eastern Townships, Quebec.

    The Canadian journal of infectious diseases = J... 24(3):138 (2013) PMID 24421824 PMCID PMC3852450

    Since July 2010, the National Advisory Committee on Immunization of Canada has recommended rotavirus vaccination for all healthy infants. However, before implementing this vaccine in routine health programs, Canadian provinces need to establish current epidemiological data on rotavirus-associate...
  7. Mo1960 Modulation of the Inflammatory Response by Epidermal Growth Factor in the Immature Human Intestine

    Gastroenterology 142(5):S (2012)

  8. Anti-inflammatory effects of epidermal growth factor on the immature human intestine.

    Physiological Genomics 44(4):268 (2012) PMID 22214601

    The inflammatory response of the preterm infants' intestine underlines its inability to respond to hemodynamic stress, microbes, and nutrients. Recent evidence suggests that exogenous epidermal growth factor (EGF) exerts a therapeutic influence on neonatal enteropathies. However, the molecular m...
  9. Gene-expression profile analysis in the mid-gestation human intestine discloses greater functional immaturity of the colon as compared with the ileum.

    Journal of Pediatric Gastroenterology and Nutri... 52(6):670 (2011) PMID 21478755

    The occurrence of many neonatal inflammatory intestinal diseases in preterm infants highlights the susceptibility of the immature intestine to responding inadequately to nutrients and microbes. A better understanding of functional intestinal development is essential for the design of optimal tre...
  10. Hypersensitivity reaction to parenteral nutrition in an intrauterine growth-restricted newborn: a case report.

    Journal of Parenteral and Enteral Nutrition 35(3):402 (2011) PMID 21383320

    Hypersensitivity reaction to parenteral nutrition (PN) in infants is a rare condition, especially in the neonatal period. The authors report the case of a neonate with intrauterine growth restriction (IUGR) who presented symptoms of anaphylaxis while receiving standard PN. Given the very common ...
  11. Luminal fermentation and colonocyte metabolism in a rat model of enteral nutrition.

    Digestive Diseases and Sciences 48(7):1339 (2003) PMID 12870792

    Large intestinal fermentation and nutrient metabolism in colonocytes were investigated in a rat model of enteral feeding. Male Wistar rats (240-280 g) were submitted to 7 or 14 days of treatment: intragastric feeding (elemental formula) versus oral feeding (isocaloric and isonitrogenous diet, co...