1. A history of the DNA repair and mutagenesis field: The discovery of base excision repair.

    DNA Repair 37:A35 (2016) PMID 26861186

    This article reviews the early history of the discovery of an DNA repair pathway designated as base excision repair (BER), since in contrast to the enzyme-catalyzed removal of damaged bases from DNA as nucleotides [called nucleotide excision repair (NER)], BER involves the removal of damaged or ...
  2. Editorial.

    DNA Repair 37:A1 (2016) PMID 26861180

  3. FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress.

    Nucleic Acids Research 43(17):8325 (2015) PMID 26187992 PMCID PMC4787816

    REV1 is a eukaryotic member of the Y-family of DNA polymerases involved in translesion DNA synthesis and genome mutagenesis. Recently, REV1 is also found to function in homologous recombination. However, it remains unclear how REV1 is recruited to the sites where homologous recombination is proc...
  4. A history of the DNA repair and mutagenesis field: I. The discovery of enzymatic photoreactivation.

    DNA Repair 33:35 (2015) PMID 26151545

    Photoreactivation, an enzyme-catalyzed reaction during which two covalently linked pyrimidine dimers in DNA are monomerized and restored to their native conformation was the first DNA repair mechanism to be discovered, an event that transpired in the late 1940's through the efforts of the Americ...
  5. Master molecule, heal thyself.

    Journal of Biological Chemistry 289(20):13691 (2014) PMID 24711456 PMCID PMC4022841

  6. Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation.

    Nucleic Acids Research 41(22):10312 (2013) PMID 24038355 PMCID PMC3905884

    Translesion DNA synthesis (TLS) can use specialized DNA polymerases to insert and/or extend nucleotides across lesions, thereby limiting stalled replication fork collapse and the potential for cell death. Recent studies have shown that monoubiquitinated proliferating cell nuclear antigen (PCNA) ...
  7. The molecular basis of mutagenesis - 40 years of research on genomic integrity.

    South African Medical Journal/Suid-Afrikaanse M... 103(12 Suppl 1):982 (2013) PMID 24300643

    This article reviews the multiple mechanisms by which both prokaryotes and eukaryotes remove or tolerate various types of naturally occurring and exogenously generated base damage in DNA. 
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  8. Increased dietary cholesterol promotes enhanced mutagenesis in DNA polymerase kappa-deficient mice.

    DNA Repair 12(10):817 (2013) PMID 23948094

    DNA polymerase kappa (Polκ) bypasses planar polycyclic N2-guanine adducts in an error-free manner. Cholesterol derivatives may interact with DNA to form similarly bulky lesions. In accordance, these studies examined whether increased mutagenesis of DNA accompanies hypercholesterolemia in Polk-/-...
  9. A life of fixing DNA.

    DNA Repair 12(6):389 (2013) PMID 23828963

  10. Mouse DNA polymerase kappa has a functional role in the repair of DNA strand breaks.

    DNA Repair 12(5):377 (2013) PMID 23522793 PMCID PMC3636179

    The Y-family of DNA polymerases support of translesion DNA synthesis (TLS) associated with stalled DNA replication by DNA damage. Recently, a number of studies suggest that some specialized TLS polymerases also support other aspects of DNA metabolism beyond TLS in vivo. Here we show that mouse p...
  11. Happy 10th birthday.

    DNA Repair 11(1):2 (2012) PMID 22226012

  12. Targeted detection of in vivo endogenous DNA base damage reveals preferential base excision repair in the transcribed strand.

    Nucleic Acids Research 40(1):206 (2012) PMID 21911361 PMCID PMC3245927

    Endogenous DNA damage is removed mainly via base excision repair (BER), however, whether there is preferential strand repair of endogenous DNA damage is still under intense debate. We developed a highly sensitive primer-anchored DNA damage detection assay (PADDA) to map and quantify in vivo endo...
  13. Autobiographical series.

    DNA Repair 10(8):800 (2011) PMID 21798466

  14. Nucleotide excision repair of DNA: The very early history.

    DNA Repair 10(7):668 (2011) PMID 21600859

    This article, taken largely from the book Correcting the Blueprint of Life: An Historical Account of the Discovery of DNA Repair Mechanisms, summarizes the very early history of the discovery of nucleotide excision repair. Copyright © 2011 Elsevier B.V. All rights reserved.
  15. Supplementary information in published manuscripts.

    DNA Repair 10(1):2 (2011) PMID 21112818

  16. A closer look at bibliometrics.

    DNA Repair 9(10):1018 (2010) PMID 20708983

  17. Peer review of scientific papers--a never-ending conundrum.

    DNA Repair 9(5):476 (2010) PMID 20378420

  18. Peer review of scientific papers--a never-ending conundrum.

    DNA Repair 9(5):476 (2010) PMID 20378420

  19. A comprehensive catalogue of somatic mutations in cancer genomes.

    DNA Repair 9(4):468 (2010) PMID 20181537

    This Hot Topics contribution considers two recently published papers that demonstrate the utility of advanced DNA sequencing technologies for identifying classes of mutations other than base substitutions. Data are presented from genome analyses of immortalized cell lines derived from a malignan...
  20. SnapShot: nucleotide excision repair.

    Cell 140(5):754 (2010) PMID 20211143