1. Corrigendum: Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax.

    Nature Communications 6:8051 (2015) PMID 26264976

  2. Glutamate mediated astrocytic filtering of neuronal activity.

    PLoS computational biology 10(12):e1003964 (2014) PMID 25521344 PMCID PMC4270452

    Neuron-astrocyte communication is an important regulatory mechanism in various brain functions but its complexity and role are yet to be fully understood. In particular, the temporal pattern of astrocyte response to neuronal firing has not been fully characterized. Here, we used neuron-astrocyte...
  3. Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax.

    Nature Communications 5:3966 (2014) PMID 24892994

    The blind mole rat (BMR), Spalax galili, is an excellent model for studying mammalian adaptation to life underground and medical applications. The BMR spends its entire life underground, protecting itself from predators and climatic fluctuations while challenging it with multiple stressors such ...
  4. Breaking the Code of Bacteria Decision Making

    Biophysical Journal 102(3):288a (2012)

  5. The effect of nondialyzable material (NDM) cranberry extract on formation of contact lens biofilm by Staphylococcus epidermidis.

    Investigative Ophthalmology & Visual Science 52(7):4929 (2011) PMID 21467179

    To assess the effects of NDM from cranberries on Staphylococcus epidermidis biofilm formed on soft contact lenses. Soft contact lenses were incubated in Tryptic Soy Broth (TSB) together with S. epidermidis (ATCC35984/RP62A) and various concentrations of NDM, and inspected by scanning electron an...
  6. Revealing voxel correlation cliques by functional holography analysis of fMRI.

    Journal of Neuroscience Methods 191(1):126 (2010) PMID 20558203

    Data acquired by functional brain imaging are of a multivariate and complex nature. Selecting relevant topographically specific information for system-level analysis is a highly non-trivial task. This challenge has traditionally been addressed by hypothesis-driven approaches. Recently, data-driv...
  7. Deciding fate in adverse times: sporulation and competence in Bacillus subtilis.

    PNAS 106(50):21027 (2009) PMID 19995980 PMCID PMC2795487

    Bacteria serve as the central arena for understanding how gene networks and proteins process information and control cellular behaviors. Recently, much effort has been devoted to the investigation of specific bacteria gene circuits as functioning modules. The next challenge is the integrative mo...
  8. The regulative role of neurite mechanical tension in network development.

    Biophysical Journal 96(4):1661 (2009) PMID 19217881 PMCID PMC2717249

    A bewildering series of dynamical processes take part in the development of the nervous system. Neuron branching dynamics, the continuous formation and elimination of neural interconnections, are instrumental in constructing distinct neuronal networks, which are the functional building blocks of...
  9. Genome holography: deciphering function-form motifs from gene expression data.

    PLoS ONE 3(7):e2708 (2008) PMID 18628959 PMCID PMC2444029

    DNA chips allow simultaneous measurements of genome-wide response of thousands of genes, i.e. system level monitoring of the gene-network activity. Advanced analysis methods have been developed to extract meaningful information from the vast amount of raw gene-expression data obtained from the m...
  10. Swarming and complex pattern formation in Paenibacillus vortex studied by imaging and tracking cells.

    BMC Microbiology 8:36 (2008) PMID 18298829 PMCID PMC2268691

    Swarming motility allows microorganisms to move rapidly over surfaces. The Gram-positive bacterium Paenibacillus vortex exhibits advanced cooperative motility on agar plates resulting in intricate colonial patterns with geometries that are highly sensitive to the environment. The cellular mechan...
  11. Target-specific and global effectors in gene regulation by MicroRNA.

    Biophysical Journal 93(11):L52 (2007) PMID 17872959 PMCID PMC2084254

    MicroRNAs are responsible for post-transcriptional gene silencing as part of critical cellular pathways and intercellular coordination, for example during embryonic development. Yet, the basic mechanism by which this silencing is accomplished is still not understood. For example, it is not known...
  12. Molecular level stochastic model for competence cycles in Bacillus subtilis.

    PNAS 104(45):17582 (2007) PMID 17962411 PMCID PMC2077070

    The role of stochasticity and noise in controlling genetic circuits is investigated in the context of transitions into and from competence in Bacillus subtilis. Recent experiments have demonstrated that bistability is not necessary for this function, but that the existence of one stable fixed po...
  13. Target-Specific and Global Effectors in Gene Regulation by MicroRNA

    Biophysical Journal 93(11):L52 (2007)

    MicroRNAs are responsible for post-transcriptional gene silencing as part of critical cellular pathways and intercellular coordination, for example during embryonic development. Yet, the basic mechanism by which this silencing is accomplished is still not understood. For example, it is not ...
  14. Seeking the foundations of cognition in bacteria: From Schrödinger's negative entropy to latent information

    Physica A: Statistical Mechanics and its Applic... 359:495 (2006)

    We reexamine Schrödinger's reflections on the fundamental requirements for life in view of new observations about bacterial self-organization and the emerging understanding of gene-network regulation mechanisms and dynamics. Focusing on the energy, matter and thermodynamic imbalances provid...
  15. Bacterial linguistic communication and social intelligence.

    Trends in Microbiology 12(8):366 (2004) PMID 15276612

    Bacteria have developed intricate communication capabilities (e.g. quorum-sensing, chemotactic signaling and plasmid exchange) to cooperatively self-organize into highly structured colonies with elevated environmental adaptability. We propose that bacteria use their intracellular flexibility, in...