1. The potential exploitation of research participants in high income countries who lack access to health care.

    British Journal of Clinical Pharmacology 81(5):857 (2016) PMID 26743927 PMCID PMC4834591

    There are millions of individuals living in North America and the European Union who lack access to healthcare services. When these individuals participate in research, they are at increased risk of being exposed to the risks and burdens of clinical trials without realizing the benefits that res...
  2. Reform of Clinical Research Regulations.

    New England Journal of Medicine 374(17):1694 (2016) PMID 27119252

  3. Risks of phase I research with healthy participants: A systematic review.

    Clinical Trials 13(2):149 (2016) PMID 26350571 PMCID PMC4783291

    Tragedies suggest that phase I trials in healthy participants may be highly risky. This possibility raises concern that phase I trials may exploit healthy participants to develop new therapies, making the translation of scientific discoveries ethically worrisome. Yet, few systematic data evaluat...
  4. Opening remarks.

    Yale journal of health policy, law, and ethics 15(1):27 (2015) PMID 25876371

  5. Perspectives on Health Care Reform and the Affordable Care Act.

    Politics and the Life Sciences 34(2):105 (2015) PMID 26742597

  6. Addressing the American health-care cost crisis: role of the oncology community.

    JNCI Journal of the National Cancer Institute 105(23):1777 (2013) PMID 24226096

    Health-care cost growth is unsustainable, and the current level of spending is harming our economy and our patients. This commentary describes the scope of the health-care spending problem and the particular factors in cancer care that contribute to the problem, reflecting in part presentations ...
  7. Refocusing the responsiveness requirement.

    Bioethics 27(3):151 (2013) PMID 21797911

    Many guidelines for international research require that studies be responsive to host community health needs or health priorities. Although responsiveness possesses great intuitive and rhetorical appeal, existing conceptions are confusing and difficult to apply. Not only are there few examples o...
  8. Community health workers combat readmission.

    Archives of Internal Medicine 172(22):1756 (2012) PMID 23128914

  9. Prevention and cost control.

    Science 337(6101):1433 (2012) PMID 22997291

  10. A systemic approach to containing health care spending.

    New England Journal of Medicine 367(10):949 (2012) PMID 22852883

  11. The quality of informed consent: mapping the landscape. A review of empirical data from developing and developed countries.

    Journal of Medical Ethics 38(6):356 (2012) PMID 22313664 PMCID PMC4825806

    Some researchers claim that the quality of informed consent of clinical research participants in developing countries is worse than in developed countries. To evaluate this assumption, we reviewed the available data on the quality of consent in both settings. We conducted a comprehensive PubMed ...
  12. Disclosing a diagnosis of cancer: where and how does it occur?

    Journal of Clinical Oncology 28(22):3630 (2010) PMID 20606078 PMCID PMC2917319

    While disclosing a cancer diagnosis to a patient is common practice, how it is disclosed and the impact it has on the patient are poorly understood. We examined how cancer diagnoses were first given to patients and the impact of different aspects of disclosure on patient satisfaction. We provide...
  13. Is emergency research without initial consent justified?: the consent substitute model.

    Archives of Internal Medicine 170(8):668 (2010) PMID 20421549

    Emergency research poses a fundamental ethical dilemma: prohibit valuable research because informed consent is not possible or enroll individuals in clinical trials without informed consent. Although emergency research without initial consent is allowable in the United States, its regulatory sta...
  14. Racial and ethnic differences in hospice use among patients with heart failure.

    Archives of Internal Medicine 170(5):427 (2010) PMID 20212178 PMCID PMC2897072

    Heart failure is the leading noncancer diagnosis for patients in hospice care and the leading cause of hospitalization among Medicare beneficiaries. Racial and ethnic differences in hospice patients are well documented for patients with cancer but poorly described for those with heart failure. O...
  15. Comprehension and informed consent: assessing the effect of a short consent form.

    IRB: Ethics and Human Research 32(4):1 (2010) PMID 20853797 PMCID PMC4819424

  16. Correction in response to the review of ethical issues in international biomedical research.

    Developing World Bioethics 9(3):167 (2009) PMID 19416346

  17. Rethinking the responsiveness requirement for international research.

    The Lancet 374(9692):847 (2009) PMID 19733781

  18. Racial and ethnic differences in end-of-life costs: why do minorities cost more than whites?

    Archives of Internal Medicine 169(5):493 (2009) PMID 19273780 PMCID PMC3621787

    Racial and ethnic minorities generally receive fewer medical interventions than whites, but racial and ethnic patterns in Medicare expenditures and interventions may be quite different at life's end. Based on a random, stratified sample of Medicare decedents (N = 158 780) in 2001, we used regres...
  19. A new federal-state partnership in health care: real power for states.

    JAMA 300(16):1931 (2008) PMID 18940982

  20. The NIH and bioethics: what should be done?

    Academic Medicine 83(6):529 (2008) PMID 18520451

    Despite the National Institute of Health's (NIH's) long tradition of engagement with and support of bioethics, the current support for bioethics is very small. Accordingly, trained bioethics researchers and bioethicists are in short supply, and fundamental ethical issues that relate to the NIH's...