1. STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large-cell lymphoma.

    Blood 126(3):336 (2015) PMID 25921060

    The tumorigenicity of most cases of ALK-positive anaplastic large-cell lymphoma (ALK+ ALCL) is driven by the oncogenic fusion protein NPM-ALK in a STAT3-dependent manner. Because it has been shown that STAT3 can be inhibited by STAT1 in some experimental models, we hypothesized that the STAT1 si...
  2. Β-defensin in Nile tilapia (Oreochromis niloticus): Sequence, tissue expression, and anti-bacterial activity of synthetic peptides.

    Gene 566(1):23 (2015) PMID 25871516

    Beta-defensins (β-defensins) are small cationic amphiphilic peptides that are widely distributed in plants, insects, and vertebrates, and are important for their antimicrobial properties. In this study, the β-defensin (Onβ-defensin) gene of the Nile tilapia (Oreochromis niloticus) was cloned fro...
  3. Label-free microRNA detection based on terbium and duplex-specific nuclease assisted target recycling.

    Analyst (Cambridge UK) 140(15):5082 (2015) PMID 26106867

    In this paper, we describe a novel label-free fluorescence method for microRNA-21 (miR-21) detection based on terbium (Tb(3+)) and duplex-specific nuclease (DSN) assisted target recycling. Capture probes (Cps), containing a target-binding part and a signal-output part, are immobilized on magneti...
  4. Zn and Sr incorporated 64S bioglasses: Material characterization, in-vitro bioactivity and mesenchymal stem cell responses.

    Materials Science and Engineering: C 52:242 (2015) PMID 25953564

    Essential element like Zn or Sr is known to play an important role in bone remodeling process. In this study, we have used the sol-gel process to synthesize the Zn (2%) and Sr (5%) doped 64S bioglasses (BGs, 64SiO2-5P2O5-31CaO, mol.%), alone and co-doped. The synthesized glasses were characteriz...
  5. Optimized hydrolysis and analysis of Radix Asparagi polysaccharide monosaccharide composition by capillary zone electrophoresis.

    Journal of Separation Science 38(13):2327 (2015) PMID 25885471

    Using orthogonal design, optimized conditions for the hydrolysis of the polysaccharide from Radix Asparagi were determined, as well as its monosaccharide composition. Optimized hydrolysis conditions were a temperature of 100°C in 1.5 M sulfuric acid solution for 5 h. The resulting monosaccharide...
  6. Epigenetic silencing of DUSP9 induces the proliferation of human gastric cancer by activating JNK signaling.

    Oncology Reports 34(1):121 (2015) PMID 25998184

    Dual-specificity phosphatase 9 (DUSP9) is a strong negative regulator of transcription factor activating kinases (ERK, JNK and p38) in the mitogen-activated protein kinase (MAPK) pathways. The aim of this study was to examine the CpG island methylation status of DUSP9 using bisulfite sequencing ...
  7. Enhanced photovoltaic performance of ZnO nanorod-based dye-sensitized solar cells by using Ga doped ZnO seed layer

    Journal of Alloys and Compounds 633:408 (2015)

    • ZnO nanorods were grown on Ga-doped ZnO seed layers using hydrothermal method. • Using the ZnO nanorods as photoanodes for fabricated dye-sensitized solar cells....
  8. Treatment of corneal perforation with lenticules from small incision lenticule extraction surgery: a preliminary study of 6 patients.

    Cornea 34(6):658 (2015) PMID 25811718

    To evaluate the use of lenticules extracted using small incision lenticule extraction (SMILE) surgery as a surgical alternative for wound closure in corneal perforation. Corneal lenticules obtained through SMILE surgery with central thickness >100 μm were fixed over corneal perforation sites usi...
  9. Allogeneic HY antibodies detected 3 months after female-to-male HCT predict chronic GVHD and nonrelapse mortality in humans.

    Blood 125(20):3193 (2015) PMID 25766725 PMCID PMC4432013

    Allogeneic antibodies against minor histocompatibility antigens encoded on the Y chromosome (HY-Abs) develop after hematopoietic cell transplant (HCT) of male recipients with female donors (F→M). However, the temporal association between HY-Ab development and chronic graft-versus-host disease (c...
  10. Effect of curing agent molecular structures on the tribological and corrosion behaviors of epoxy resin coatings

    Colloids and Surfaces A: Physicochemical and En... 472:85 (2015)

    Fracture surfaces morphologies of EP coatings cured by three kinds of curing agents with different molecular structures. (a) DETA cured; (b) IPDA cured and (c) m-PDA cured.
  11. [Effect of emodin on proliferation and cell cycle of human oral squamous carcinoma Tca8113 cells in vitro].

    Nan fang yi ke da xue xue bao = Journal of Sout... 35(5):665 (2015) PMID 26018259

    To investigate the effect of emodin on proliferation and cell cycle distribution of human oral squamous carcinoma cells in vitro. Cultured human oral squamous carcinoma Tca8113 cells were treated with 2.5, 5, 10, 20, 40, 60 and 80 µmol/L emodin for 24, 48 or 72 h, with the cells treated with 0.1...
  12. Step-wise support vector machines for classification of overlapping samples

    Neurocomputing 155:159 (2015)

    Among machine learning algorithms, Support Vector Machine (SVM) is outstanding for its high efficiency and good generalization ability. This paper mainly concerns the classification performance of SVMs for multiple classes and auxiliary algorithms combined with SVMs. These auxiliary al...
  13. Step-wise support vector machines for classification of overlapping samples

    Neurocomputing 155:159 (2015)

    Among machine learning algorithms, Support Vector Machine (SVM) is outstanding for its high efficiency and good generalization ability. This paper mainly concerns the classification performance of SVMs for multiple classes and auxiliary algorithms combined with SVMs. These auxiliary al...
  14. Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.

    European Journal of Cancer 51(8):969 (2015) PMID 25843513 PMCID PMC4467782

    Several somatic mutation hotspots were recently identified in the telomerase reverse transcriptase (TERT) promoter region in human cancers. Large scale studies of these mutations in multiple tumour types are limited, in particular in Asian populations. This study aimed to: analyse TERT promoter ...
  15. Step-wise support vector machines for classification of overlapping samples

    Neurocomputing 155:159 (2015)

    Among machine learning algorithms, Support Vector Machine (SVM) is outstanding for its high efficiency and good generalization ability. This paper mainly concerns the classification performance of SVMs for multiple classes and auxiliary algorithms combined with SVMs. These auxiliary al...
  16. Triple negative breast cancers comprise a highly tumorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulatory region 2 (SRR2) reporter.

    Oncotarget 6(12):10366 (2015) PMID 25868977 PMCID PMC4496361

    We have recently described a novel phenotypic dichotomy within estrogen receptor-positive breast cancer cells; the cell subset responsive to a Sox2 regulatory region (SRR2) reporter (RR cells) are significantly more tumorigenic than the reporter unresponsive (RU) cells. Here, we report that a si...
  17. Rejection prediction of isopropylantipyrine and antipyrine by nanofiltration membranes based on the Spiegler–Kedem–Katchalsky model

    Desalination 362:11 (2015)

    The Spiegler–Kedem–Katchalsky (SKK) model has been used to predict the rejection of isopropylantipyrine (AMT) and antipyrine (ANT) in a cross-flow with NF-W membrane cell at 25°C. In this model, the mass transfer parameters σ and Ps were obtained using the best-fit method. The permeate...
  18. Group IIE secretory phospholipase A2 regulates lipolysis in adipocytes.

    Obesity 23(4):760 (2015) PMID 25755141

    To examine the function of group IIE secretory phospholipase A(2) (sPLA(2) -IIE) in adipocytes and to explore the possible signaling mechanism involved. The expression of sPLA(2) -IIE was demonstrated using real-time PCR and Western blot analysis. Lipid accumulation was evaluated via the measure...
  19. Color image segmentation using PDTDFB domain hidden Markov tree model

    Applied Soft Computing 29:138 (2015)

    The PDTDFB domain hidden Markov tree (HMT) model, where the white nodes represent the hidden state and the black nodes represent the PDTDFB transform coefficient associated with that hidden state and the links between the white nodes capture the dependences across scales: (a) 4–4 decomposition st...
  20. Correlation of creatine kinase with patency of stents using coronary computed tomography angiography.

    Zhongguo yi xue ke xue yuan xue bao. Acta Acade... 37(2):140 (2015) PMID 25936700

    To explore the potential correlation between creatine kinase and the long-term patency of coronary drug eluting stents. The clinical data of 74 patients who had undergone coronary computed tomography angiography after drug eluting stents implantation were retrospecpectively analyzed. Based on th...