Advanced search×
  1. Erratum to: Comparative In Vivo Evaluations of Curcumin and Its Analog Difluorinated Curcumin Against Cisplatin-Induced Nephrotoxicity.

    Biological Trace Element Research 164(1):162 (2015) PMID 25488703

  2. Androgen receptor splice variants contribute to prostate cancer aggressiveness through induction of EMT and expression of stem cell marker genes.

    Prostate 75(2):161 (2015) PMID 25307492 PMCID PMC4270852

    The mechanism(s) by which androgen receptor (AR) splice variants contribute to castration-resistant prostate cancer (CRPC) is still lacking. Expressions of epithelial-to-mesenchymal transition (EMT) and stem cell markers were molecularly tested using prostate cancer (PCa) cells transfected with ...
  3. Overview on the complexity of androgen receptor-targeted therapy for prostate cancer.

    Cancer Cell International 15:7 (2015) PMID 25705125 PMCID PMC4336517

    In the past decades, the field of prostate cancer (PCa) biology has developed exponentially and paralleled with that has been the growing interest in translation of laboratory findings into clinical practice. Based on overwhelming evidence of high impact research findings which support the under...
  4. Molecular targets of naturopathy in cancer research: bridge to modern medicine.

    Nutrients 7(1):321 (2015) PMID 25569626 PMCID PMC4303842

    The relevance of naturopathy (defined as the practice of medicine for the treatment of human diseases with natural agents) in human cancer is beginning to be appreciated, as documented by renewed interest in nutraceutical research, the natural anticancer agents of dietary origin. Because of thei...
  5. Recent progress on nutraceutical research in prostate cancer.

    Cancer and Metastasis Reviews 33(2-3):629 (2014) PMID 24375392 PMCID PMC4074449

    Recently, nutraceuticals have received increasing attention as the agents for cancer prevention and supplement with conventional therapy. Prostate cancer (PCa) is the most frequently diagnosed cancer and second leading cause of cancer-related death in men in the US. Growing evidences from epidem...
  6. Differentially expressed miRNAs in cancer-stem-like cells: markers for tumor cell aggressiveness of pancreatic cancer.

    Stem Cells and Development 23(16):1947 (2014) PMID 24734907

    Pancreatic cancer (PC) is one of the most deadly cancers. The higher mortality is in part due to treatment resistance and early onset of metastasis. The existence of cancer-stem-like cells (CSLCs) has been widely accepted to be responsible for tumor aggressiveness in PC. Emerging evidence sugges...
  7. The therapeutic potential of targeting the epithelial-mesenchymal transition in cancer.

    Expert Opinion on Therapeutic Targets 18(7):731 (2014) PMID 24758643

    The process of epithelial-to-mesenchymal transition (EMT) has long been advocated as a process during tumor progression and the acquisition of metastatic potential of human cancers. EMT has also been linked with resistance to cancer therapies. Basic research has provided evidence connecting EMT ...
  8. Metformin may function as anti-cancer agent via targeting cancer stem cells: the potential biological significance of tumor-associated miRNAs in breast and pancreatic cancers.

    Annals of translational medicine 2(6):59 (2014) PMID 25333034 PMCID PMC4200664

    Metformin is one of the most used diabetic drugs for the management of type II diabetes mellitus (DM) in the world. Increased numbers of epidemiological and clinical studies have provided convincing evidence supporting the role of metformin in the development and progression of a variety of huma...
  9. Pancreatic cancer stem-like cells display aggressive behavior mediated via activation of FoxQ1.

    Journal of Biological Chemistry 289(21):14520 (2014) PMID 24719318 PMCID PMC4031510

    Subpopulations of cancer stem cells (CSCs) or cancer stem-like cells (CSLCs) have been identified from most tumors, including pancreatic cancer (PC), and the existence of these cells is clinically relevant. Emerging evidence suggests that CSLCs participate in cell growth/proliferation, migration...
  10. Advances in androgen receptor targeted therapy for prostate cancer.

    Journal Of Cellular Physiology 229(3):271 (2014) PMID 24037862 PMCID PMC3838461

    Prostate cancer (PCa) is the second leading cause of cancer death in men. Current research findings suggest that the androgen receptor (AR) and its signaling pathway contribute significantly to the progression of metastatic PCa. The AR is a ligand activated transcription factor, where androgens ...