The effect of symmetrical and asymmetrical hearing impairment on music quality perception.
Archiv fÃ¼r Ohren- Nasen- und Kehlkopfheilkunde 273(9):2451 (2016)
The purpose of this study was to investigate the effect of symmetrical, asymmetrical and unilateral hearing impairment on music quality perception. Six validated music pieces in the categories of classical music, folk music and pop music were used to assess music quality in terms of its 'pleasan...
Juvenile zebrafish in the vitellogenin blank period as an alternative test organism for evaluation of estrogenic activity of chemicals.
Environmental Toxicology and Chemistry 35(7):1783 (2016)
The present study aimed to determine the suitable development period for zebrafish to evaluate estrogenic activities accurately. An enzyme-linked immunosorbent assay was developed and used to detect the vitellogenin (Vtg)-derived yolk proteins and newly produced Vtg, and 9 d to 56 d posthatching...
The synthesis and synergistic antifungal effects of chalcones against drug resistant Candida albicans.
Bioorganic & Medicinal Chemistry Letters 26(13):3098 (2016)
To identify effective and low toxicity synergistic antifungal compounds, 24 derivatives of chalcone were synthesized to restore the effectiveness of fluconazole against fluconazole-resistant Candida albicans. The minimal inhibitory concentration (MIC80) and the fractional inhibitory concentratio...
Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan.
Molecular Neurobiology 53(5):3494 (2016)
Dextromethorphan (DM) is a non-competitive antagonist of NMDA receptors and a widely used component of cough medicine. Recently, its indication has been extended experimentally to a wide range of disorders including inflammation-mediated central nervous system disorders such as Parkinson disease...
Boron-Doped Anatase TiO2 as a High-Performance Anode Material for Sodium-Ion Batteries.
ACS Applied Materials & Interfaces 8(25):16009 (2016)
Pristine and boron-doped anatase TiO2 were prepared via a facile sol-gel method and the hydrothermal method for application as anode materials in sodium-ion batteries (SIBs). The sol-gel method leads to agglomerated TiO2, whereas the hydrothermal method is conducive to the formation of highly cr...
Pomegranate extract and exercise provide additive benefits on improvement of immune function by inhibiting inflammation and oxidative stress in high-fat-diet-induced obesity in rats.
The Journal of Nutritional Biochemistry 32:20 (2016)
Obesity is reported to be associated with immune dysfunction and a state of low-grade, chronic inflammation. Either pomegranate extract (PomE) or exercise (Ex) has been shown to have antiobesity, anti-inflammatory and antioxidant effects. Nevertheless, no study has addressed the additive benefit...
Multipotent mesenchymal stromal cells are fully permissive for human cytomegalovirus infection.
Virologica Sinica 31(3):219 (2016)
Congenital human cytomegalovirus (HCMV) infection is a leading infectious cause of birth defects. Previous studies have reported birth defects with multiple organ maldevelopment in congenital HCMV-infected neonates. Multipotent mesenchymal stromal cells (MSCs) are a group of stem/progenitor cell...
Inhibition of Glut1 by WZB117 sensitizes radioresistant breast cancer cells to irradiation.
Cancer Chemotherapy and Pharmacology 77(5):963 (2016)
Breast cancer is the most common type of cancer with high incidence in women. Currently, identifying new therapies that selectively inhibit tumor growth without damaging normal tissue are a major challenge of cancer research. One of the features of cancer cells is that they do not consume more o...
A General and Extremely Simple Remote Approach toward Graphene Bulks with In Situ Multifunctionalization.
Advanced Materials (FRG) 28(17):3305 (2016)
Functional graphene bulks are developed by a general and simple approach for largescale preparation. This method shows promise for energy-related applications.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Identification and BAC construction of Han, the first characterized HCMV clinical strain in China.
Journal of Medical Virology 88(5):859 (2016)
Human cytomegalovirus (HCMV) is the leading infectious cause of birth defects, and may lead to severe or lethal diseases in immunocompromised individuals. Several HCMV strains have been identified and widely applied in research, but no isolate from China has been characterized. In the present st...
Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α1A-Adrenoceptor Antagonists.
Journal of medicinal and pharmaceutical chemistry 59(8):3826 (2016)
A series of indoline and indole derivatives were designed, synthesized, and evaluated as selective α1A-adrenergic receptor (α1A-AR) antagonists for the treatment of benign prostatic hyperplasia (BPH). In this study, two highly selective and potent α1A-AR antagonists, compounds (R)-14r (IC50 = 2....
Entropic Ligands for Nanocrystals: From Unexpected Solution Properties to Outstanding Processability.
Nano Letters 16(4):2133 (2016)
Solution processability of nanocrystals coated with a stable monolayer of organic ligands (nanocrystal-ligands complexes) is the starting point for their applications, which is commonly measured by their solubility in media. A model described in the other report (10.1021/acs.nanolett.6b00737) re...
Sodium selenite suppresses hepatitis B virus transcription and replication in human hepatoma cell lines.
Journal of Medical Virology 88(4):653 (2016)
Hepatitis B virus (HBV) infection is one of the most serious and prevalent health problems worldwide. Current anti-HBV medications have a number of drawbacks, such as adverse effects and drug resistance; thus, novel potential anti-HBV reagents are needed. Selenium (Se) has been shown to be invol...
Inhibitory effect of oridonin on proliferation of RPMI8226 cells and the possible underlying mechanism.
Journal of traditional Chinese medicine = Chung... 36(2):225 (2016)
To observe the effects of oridonin on proliferation and apoptosis of myeloma RPMI8226 cells and to investigate the potential underlying mechanisms.
RPMI8226 cells were treated with various concentrations of oridonin. Cell proliferation was analyzed using the thiazolyl blue tetrazolium bromide me...
MiR-26b inhibits autophagy by targeting ULK2 in prostate cancer cells.
Biochemical and Biophysical Research Communicat... 472(1):194 (2016)
Autophagy is a catabolic process widely conserved among eukaryotes that permits the rapid degradation of unwanted proteins and organelles through the lysosomal pathway. The Serine/threonine protein kinase ULK2 (unc-51 like kinase 2) plays an important regulatory role in autophagy thanks to its i...
Triptolide induces protective autophagy through activation of the CaMKKβ-AMPK signaling pathway in prostate cancer cells.
Oncotarget 7(5):5366 (2016)
Triptolide, an active compound extracted from the Chinese herb thunder god vine (Tripterygium wilfordii Hook F.), has potent anti-tumor activity. Recently, triptolide was found to induce autophagy in cancer cells. However, the effects of triptolide on autophagy in human prostate cancer (PCa) cel...
Fabrication of the Optical Fiber GABA Sensor Based on the NADP+ -Functionalized Quantum Dots.
Journal of Nanoscience and Nanotechnology 16(2):1429 (2016)
A novel quantum dots (QDs)-based optical fiber biosensor has been developed to detect gamma-amino butyric acid (GABA) directly, via QD fluorescence quenching and recovery. QDs were immobilized on the surface of an optical-fiber through the EDC/Sulfo-NHS coupling reaction. The QDs were functional...
Effects of Chinese yellow wine on nitric oxide synthase and intercellular adhesion molecule-1 expressions in rat vascular endothelial cells.
Acta Cardiologica 71(1):27 (2016)
The objective of this study was to determine similarities in the effect of yellow wine as compared to statin and the possibility that yellow wine inhibits tumour necrosis factor-α (TNF-α)-induced nitric oxide (NO) synthesis, endothelial nitric oxide synthase (eNOS), inducible nitric oxide syntha...
Doped Semiconductor-Nanocrystal Emitters with Optimal Photoluminescence Decay Dynamics in Microsecond to Millisecond Range: Synthesis and Applications.
Transition metal doped semiconductor nanocrystals (d-dots) possess fundamentally different emission properties upon photo- or electroexcitation, which render them as unique emitters for special applications. However, in comparison with intrinsic semiconductor nanocrystals, the potential of d-dot...
Mesoporous Li4Ti5O12 nanoclusters anchored on super-aligned carbon nanotubes as high performance electrodes for lithium ion batteries.
Nanoscale 8(1):617 (2016)
Mesoporous lithium titanate (LTO) nanoclusters are in situ synthesized in a network of super aligned carbon nanotubes (SACNTs) via a solution-based method followed by heat treatment in air. In the LTO-CNT composite, SACNTs not only serve as the skeleton to support a binder-free electrode, but al...