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  1. Positive energy balance is associated with accelerated muscle atrophy and increased erythrocyte glutathione turnover during 5 wk of bed rest...

    American Journal of Clinical Nutrition 88(4):950 (2008) PMID 18842781

    We aimed to assess whether energy intake in excess of requirement activates systemic inflammation and antioxidant defenses and accelerates muscle atrophy induced by inactivity. Nineteen healthy male volunteers were studied before and at the end of 5 wk of bed rest. Subjects were allowed to spontaneo...
  2. Blood glucose changes in diabetic children and adolescents engaged in most common sports activities.

    Acta bio-medica de L'Ateneo parmense : organo d... 77 Suppl 1:26 (2006) PMID 16921609

    Circulating insulin levels decrease and substrate glycogenolysis-mediated conversion into glucose increases just a few minutes after normal subjects start exercising, but during sustained physical activity muscles massively utilize blood glucose, thus causing glycogenolysis to increase further until...
  3. Frailty and safety: the example of diabetes.

    Drug Safety 35 Suppl 1:63 (2012) PMID 23446787

    We will discuss injection treatment with GLP-1 analogues. This review will underline the association between diabetes and some frailty components in old patients and how specific antidiabetic agents may play a specific role in improving outcomes....
  4. Changes in stress hormones and metabolism during a 105-day simulated Mars mission.

    Aviation, Space, and Environmental Medicine 85(8):793 (2014) PMID 25199119

    The Mars-105 project was aimed at simulating crew's activities, workload, and communication during a mission to Mars, evaluating the homeostatic adaptations to prolonged confinement and cohabitation. Fasting plasma glucose (FPG) and insulin, C-peptide, leptin, cortisol, and NGF and BDNF plasma level...
  5. Deficits in visuo-spatial but not in topographical memory during pregnancy and the postpartum state in an expert military pilot: a case repo...

    BMC Research Notes 7:524 (2014) PMID 25115346 PMCID PMC4138368

    We describe the changes in reaching and walking memory that occurred during pregnancy and one year after delivery in an Italian female military pilot (Case 1) with high spatial ability. In memory tests she showed a classical dissociation between performance in reaching and walking distance, which in...
  6. Sleep apnea, sleep disturbance, and fasting glucose variability: a pilot study.

    Journal of diabetes science and technology (Onl... 7(3):743 (2013) PMID 23759408 PMCID PMC3869143

    Disturbed sleep and nocturnal altered breathing are related to disturbances of glucose metabolism. The present uncontrolled observational study explores the role of these factors on the variability of fasting glycemia. The number and duration of nocturnal awakenings and the fasting glycemia of 97 pa...
  7. Adipokines and Sexual Hormones Associated with the Components of the Metabolic Syndrome in Pharmacologically Untreated Subjects: Data from t...

    International Journal of Endocrinology 2011 :1 (2011) PMID 22114592

    We evaluated the association of the sex hormone pattern and the serum level of the main adipokines to metabolic syndrome (MS) and its components in 199 pharmacologically untreated subjects. Men and women included in the age-class subgroups were matched for body mass index, waist circumference, blood...
  8. A short term −12° head down tilt does not mimic microgravity in terms of human gonadal function

    Microgravity - Science and Technology 18(3):226 (2006)

  9. Microgravity as a model of ageing.

    Current Opinion in Clinical Nutrition and Metab... 6(1):31 (2003) PMID 12496678

    Longevity with good health and long-term survival in space are two of the many challenges that scientists face in the twenty-first century. Ageing and life in space are both associated with undesirable effects on normal physiological processes. This review will outline how the endocrine, metabolic,...
  10. Clinorotation-induced weightlessness influences the cytoskeleton of glial cells in culture

    Brain Research 934(2):132 (2002) PMID 11955476

    We undertook a ground based research using a random positioning machine (clinostat) as a simulation method for microgravity. The outcome of the study was represented by cytoskeletal changes occurring in cultured glial cells (C 6 line) after 15 min, 30 min, 1 h, 20 h and 32 h under simulated mi...