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  1. Effects of Aerobic Exercise Based upon Heart Rate at Aerobic Threshold in Obese Elderly Subjects with Type 2 Diabetes.

    International Journal of Endocrinology 2015:695297 (2015) PMID 26089890 PMCID PMC4452101

    In obese diabetic subjects, a correct life style, including diet and physical activity, is part of a correct intervention protocol. Thus, the aim of this study was to evaluate the effects of aerobic training intervention, based on heart rate at aerobic gas exchange threshold (AerTge), on clinica...
  2. Changes in stress hormones and metabolism during a 105-day simulated Mars mission.

    Aviation, Space, and Environmental Medicine 85(8):793 (2014) PMID 25199119

    The Mars-105 project was aimed at simulating crew's activities, workload, and communication during a mission to Mars, evaluating the homeostatic adaptations to prolonged confinement and cohabitation. Fasting plasma glucose (FPG) and insulin, C-peptide, leptin, cortisol, and NGF and BDNF plasma l...
  3. Different prevalence of metabolic control and chronic complication rate according to the time of referral to a diabetes care unit in the elderly.

    Acta Diabetologica 51(3):447 (2014) PMID 24366424

    The time of diagnosis is crucial for type 2 diabetes mellitus (T2DM) in terms of disease severity and chronic complications, as initial glycated haemoglobin (HbA1c) predicts 5-year cardiovascular mortality. The Italian health-care system relies on about 650 diabetes care units (DCU) interfacing ...
  4. Application of technology in endocrine disease.

    International Journal of Endocrinology 2014:715029 (2014) PMID 24688544 PMCID PMC3945073

  5. Deficits in visuo-spatial but not in topographical memory during pregnancy and the postpartum state in an expert military pilot: a case report.

    BMC Research Notes 7:524 (2014) PMID 25115346 PMCID PMC4138368

    It is well known that cognitive and emotional changes occur during pregnancy, but little is known about their magnitude or their time of occurrence and recovery. During pregnancy memory is one of the most impaired cognitive functions. Although long-term aspects of memory have been investigated, ...
  6. Mental rotation task in a pilot during and after pregnancy.

    Aviation, Space, and Environmental Medicine 84(10):1092 (2013) PMID 24261064

    Discordant findings have been reported about the change in pregnant women's cognitive test performance. Visuo-spatial abilities, which are crucial in terrestrial/flight navigation, could be influenced by hormonal variations. A 32-yr-old Italian Air Force pilot underwent a 2-D Mental Rotation Tas...
  7. Low-intermediate dose testosterone replacement therapy by different pharmaceutical preparations improves frailty score in elderly hypogonadal hyperglycaemic patients.

    The Aging Male 16(2):33 (2013) PMID 23517433

    An open-label follow-up study of low-to-intermediate dose testosterone replacement therapy (TRT) was conducted in 64 overweight patients (aged 65-75 years) with late onset hypogonadism (LOH) and increased fasting plasma glucose (FPG). Patients were subdivided into four treatment groups: oral tes...
  8. Screening of Cushing's syndrome in outpatients with type 2 diabetes: results of a prospective multicentric study in Italy.

    Journal of Clinical Endocrinology & Metabolism 97(10):3467 (2012) PMID 22767639

    Cushing's syndrome may remain unrecognized among patients referred for metabolic syndrome; thus, a proactive screening has been suggested in certain patient populations with features of the disorder. However, conflicting data have been reported on the prevalence of Cushing's syndrome in patients...
  9. The impact of long-term exposure to space environment on adult mammalian organisms: a study on mouse thyroid and testis.

    PLoS ONE 7(4):e35418 (2012) PMID 22558148 PMCID PMC3338839

    Hormonal changes in humans during spaceflight have been demonstrated but the underlying mechanisms are still unknown. To clarify this point thyroid and testis/epididymis, both regulated by anterior pituitary gland, have been analyzed on long-term space-exposed male C57BL/10 mice, either wild typ...
  10. Frailty and safety: the example of diabetes.

    Drug Safety 35 Suppl 1:63 (2012) PMID 23446787

    Frailty is considered a syndrome of decreased reserve and resistance to stressors and is clinically expressed as muscle weakness, poor exercise tolerance, factors related to body composition, sarcopenia and disability. In addition, there is a close relationship between age-related metabolic chan...