1. Monthly ibandronate versus weekly risedronate treatment for low bone mineral density in stable renal transplant patients.

    Nuclear Medicine Communications 36(8):815 (2015) PMID 25856225

    Bisphosphonates may aid in treating and preventing bone loss promoted by chronic immunosuppressive treatment and secondary hyperparathyroidism in renal transplant (RT) patients. However, the effectiveness of bisphosphonates is compromised by poor patient compliance. The objective of the study wa...
  2. Blood glutamate grabbing does not reduce the hematoma in an intracerebral hemorrhage model but it is a safe excitotoxic treatment modality.

    Journal of Cerebral Blood Flow and Metabolism 35(7):1206 (2015) PMID 25735920

    Recent studies have shown that blood glutamate grabbing is an effective strategy to reduce the excitotoxic effect of extracellular glutamate released during ischemic brain injury. The purpose of the study was to investigate the effect of two of the most efficient blood glutamate grabbers (oxaloa...
  3. Rapid calcitriol increase and persistent calcidiol insufficiency in the first 6 months after kidney transplantation.

    Nuclear Medicine Communications 36(5):489 (2015) PMID 25603274

    Vitamin D deficiency or insufficiency is prevalent in kidney transplant recipients. Little is known about post-transplantation changes in vitamin D forms, which are essential for bone health and other health outcomes. The aim was to measure the levels of calcidiol and calcitriol during the first...
  4. A genetic risk score is associated with hepatic triglyceride content and non-alcoholic steatohepatitis in Mexicans with morbid obesity

    Experimental and Molecular Pathology 98(2):178 (2015)

    Background and aims Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) near/in PNPLA3, NCAN, LYPLAL1, PPP1R3B, and GCKR genes associated with non-alcoholic fatty liver disease (NAFLD) mainly in individuals of European ancestry. The aim of t...
  5. DXA Variations and Fractures After Simultaneous Pancreas-Renal Transplantation: Results of a Long-Term Follow-up.

    Clinical Nuclear Medicine 40(4):e232 (2015) PMID 25525928

    Simultaneous pancreas-kidney transplant (SPKT) has been associated with an increased risk of fracture. We prospectively evaluated the long-term effects of SPKT on bone mineral density (BMD) and fracture risk. During 1998 to 1999, 29 participants were consecutively monitored, and 18 completed the...
  6. DXA Variations and Fractures After Simultaneous Pancreas-Renal Transplantation: Results of a Long-Term Follow-up.

    Clinical Nuclear Medicine 40(4):e232 (2015) PMID 25525928

    Simultaneous pancreas-kidney transplant (SPKT) has been associated with an increased risk of fracture. We prospectively evaluated the long-term effects of SPKT on bone mineral density (BMD) and fracture risk. During 1998 to 1999, 29 participants were consecutively monitored, and 18 completed the...
  7. Efficacy of continuous positive airway pressure treatment on 5-year survival in patients with ischaemic stroke and obstructive sleep apnea: a randomized controlled trial.

    Journal of Sleep Research 24(1):47 (2015) PMID 25040553

    The main purpose of the present analysis is to assess the influence of introducing early nasal continuous positive airway pressure (nCPAP) treatment on cardiovascular recurrences and mortality in patients with a first-ever ischaemic stroke and moderate-severe obstructive sleep apnea (OSA) with a...
  8. Efficacy of continuous positive airway pressure treatment on 5-year survival in patients with ischaemic stroke and obstructive sleep apnea: a randomized controlled trial.

    Journal of Sleep Research 24(1):47 (2015) PMID 25040553

    The main purpose of the present analysis is to assess the influence of introducing early nasal continuous positive airway pressure (nCPAP) treatment on cardiovascular recurrences and mortality in patients with a first-ever ischaemic stroke and moderate-severe obstructive sleep apnea (OSA) with a...
  9. Study of Protein Expresion in Peri-Infarct Tissue after Cerebral Ischemia.

    Scientific reports 5:12030 (2015) PMID 26153530 PMCID PMC4495553

    In this work, we report our study of protein expression in rat peri-infarct tissue, 48 h after the induction of permanent focal cerebral ischemia. Two proteomic approaches, gel electrophoresis with mass spectrometry and combined fractional diagonal chromatography (COFRADIC), were performed using...
  10. White matter injury restoration after stem cell administration in subcortical ischemic stroke.

    Stem Cell Research & Therapy 6(1):121 (2015) PMID 26088123 PMCID PMC4513704

    Despite its high incidence, nerve fiber (axon and myelin) damage after cerebral infarct has not yet been extensively investigated. The aim of this study was to investigate white matter repair after adipose-derived mesenchymal stem cell (ADMSC) administration in an experimental model of subcortic...
  11. Learning from the experiments that never happened: Lessons from trying to conduct randomized evaluations of matching grant programs in Africa

    Journal of the Japanese and International Econo... 33:4 (2014)

    • Matching grants are one of the most common policy instruments used by developing country. • One critique of development research is publication bias. ...
  12. Regulatory T cells modulate inflammation and reduce infarct volume in experimental brain ischaemia.

    Journal of Cellular and Molecular Medicine 18(8):1571 (2014) PMID 24889329 PMCID PMC4190903

    Brain ischaemia (stroke) triggers an intense inflammatory response predominately mediated by the accumulation of inflammatory cells and mediators in the ischaemic brain. In this context, regulatory T (Treg) cells, a subpopulation of CD4(+) T cells with immunosuppressive and anti-inflammatory pro...
  13. Regulatory T cells modulate inflammation and reduce infarct volume in experimental brain ischaemia.

    Journal of Cellular and Molecular Medicine 18(8):1571 (2014) PMID 24889329 PMCID PMC4190903

    Brain ischaemia (stroke) triggers an intense inflammatory response predominately mediated by the accumulation of inflammatory cells and mediators in the ischaemic brain. In this context, regulatory T (Treg) cells, a subpopulation of CD4(+) T cells with immunosuppressive and anti-inflammatory pro...
  14. Bone marrow mesenchymal stem cells from patients with aplastic anemia maintain functional and immune properties and do not contribute to the pathogenesis of the disease.

    Haematologica 99(7):1168 (2014) PMID 24727813 PMCID PMC4077077

    Aplastic anemia is a life-threatening bone marrow failure disorder characterized by peripheral pancytopenia and marrow hypoplasia. The majority of cases of aplastic anemia remain idiopathic, although hematopoietic stem cell deficiency and impaired immune responses are hallmarks underlying the bo...
  15. Obstructive sleep apnea is associated with cancer mortality in younger patients.

    Sleep Medicine 15(7):742 (2014) PMID 24907033

    The association between obstructive sleep apnea (OSA) and cancer mortality has scarcely been studied. The objective of this study was to investigate whether OSA is associated with increased cancer mortality in a large cohort of patients with OSA suspicion. This was a multicenter study in consecu...
  16. Bone marrow mesenchymal stem cells from patients with aplastic anemia maintain functional and immune properties and do not contribute to the pathogenesis of the disease.

    Haematologica 99(7):1168 (2014) PMID 24727813 PMCID PMC4077077

    Aplastic anemia is a life-threatening bone marrow failure disorder characterized by peripheral pancytopenia and marrow hypoplasia. The majority of cases of aplastic anemia remain idiopathic, although hematopoietic stem cell deficiency and impaired immune responses are hallmarks underlying the bo...
  17. Role of sleep apnea and continuous positive airway pressure therapy in the incidence of stroke or coronary heart disease in women.

    American Journal of Respiratory and Critical Ca... 189(12):1544 (2014) PMID 24673616

    It is unknown whether obstructive sleep apnea (OSA) may be a risk factor for incident cardiovascular events in women. We sought to investigate whether OSA increases the incidence of a composite of stroke or coronary heart disease (CHD) in women, and the role of continuous positive airway pressur...
  18. Association between sleep disordered breathing and aggressiveness markers of malignant cutaneous melanoma.

    European Respiratory Journal 43(6):1661 (2014) PMID 24659545

    Some recent studies have shown an association between sleep disordered breathing (SDB) and cancer mortality and incidence but no study has focused on a specific type of cancer. The objective of this study was to analyse the relationship between the severity of SDB and factors related to cutaneou...
  19. Association between sleep disordered breathing and aggressiveness markers of malignant cutaneous melanoma.

    European Respiratory Journal 43(6):1661 (2014) PMID 24659545

    Some recent studies have shown an association between sleep disordered breathing (SDB) and cancer mortality and incidence but no study has focused on a specific type of cancer. The objective of this study was to analyse the relationship between the severity of SDB and factors related to cutaneou...
  20. CPAP and reduced blood pressure--reply.

    JAMA 311(19):2022 (2014) PMID 24846043