1. H3K4 acetylation, H3K9 acetylation and H3K27 methylation in breast tumor molecular subtypes.

    Epigenomics 8(7):909 (2016) PMID 27424567

    Here, we investigated how the St Gallen breast molecular subtypes displayed distinct histone H3 profiles. 192 breast tumors divided into five St Gallen molecular subtypes (luminal A, luminal B HER2-, luminal B HER2+, HER2+ and basal-like) were evaluated for their histone H3 modifications on gene...
  2. The JMJD3 Histone Demethylase and the EZH2 Histone Methyltransferase in Prostate Cancer.

    OMICS: A Journal of Integrative Biology 20(2):123 (2016) PMID 26871869

  3. Genome-wide DNA methylation modified by soy phytoestrogens: role for epigenetic therapeutics in prostate cancer?

    OMICS: A Journal of Integrative Biology 19(4):209 (2015) PMID 25831061

    In prostate cancer, DNA methylation is significantly associated with tumor initiation, progression, and metastasis. Previous studies have suggested that soy phytoestrogens might regulate DNA methylation at individual candidate gene loci and that they play a crucial role as potential therapeutic ...
  4. Prostate cancer: The main risk and protective factors-Epigenetic modifications.

    Annales d'Endocrinologie 76(1):25 (2015) PMID 25592466

    With 13 million new cases worldwide every year, prostate cancer is as a very real public health concern. Prostate cancer is common in over-50s men and the sixth-leading cause of cancer-related death in men worldwide. Like all cancers, prostate cancer is multifactorial - there are non-modifiable ...
  5. The Role of Soy Phytoestrogens on Genetic and Epigenetic Mechanisms of Prostate Cancer.

    The enzymes / edited by Paul D. Boyer 37:193 (2015) PMID 26298461

    Soy phytoestrogens are dietary components with considerable effects on reducing the incidence of prostate cancer. Epidemiological studies demonstrated that occurrence of prostate cancer is relatively low in Asia and Southern Europe, a status associated with consuming of soy isoflavones, such as ...
  6. A bivalent role of TIP60 histone acetyl transferase in human cancer.

    Epigenomics 7(8):1351 (2015) PMID 26638912

    Acetylation is a major modification that is required for gene regulation, genome maintenance and metabolism. A dysfunctional acetylation plays an important role in several diseases, including cancer. A group of enzymes-lysine acetyltransferases are responsible for this modification and act in re...
  7. Epigenetics of prostate cancer: distribution of histone H3K27me3 biomarkers in peri-tumoral tissue.

    OMICS: A Journal of Integrative Biology 18(3):207 (2014) PMID 24517089

  8. Epigenetic mechanisms of breast cancer: an update of the current knowledge.

    Epigenomics 6(6):651 (2014) PMID 25531258

    Epigenetic alterations are heritable changes in gene expression that occur without causing any change in DNA sequence. They are important key factors for cancer development and prognosis. Breast cancer is induced by the accumulation of altered gene regulation. Besides genetic mutations, epigenet...
  9. Epigenetic modifications in prostate cancer.

    Epigenomics 6(4):415 (2014) PMID 25333850

    Prostate cancer is the most common cancer in men and the second leading cause of cancer deaths in men in France. Apart from the genetic alterations in prostate cancer, epigenetics modifications are involved in the development and progression of this disease. Epigenetic events are the main cause ...
  10. The association between histone 3 lysine 27 trimethylation (H3K27me3) and prostate cancer: relationship with clinicopathological parameters.

    BMC Cancer 14:994 (2014) PMID 25535400 PMCID PMC4364597

    It is well established that genetic and epigenetic alterations are common events in prostate cancer, which may lead to aberrant expression of critical genes. The importance of epigenetic mechanisms in prostate cancer carcinogenesis is increasingly evident. In this study, the focus will be on his...