1. IMGT®, the international ImMunoGeneTics information system® 25 years on.

    Nucleic Acids Research 43(Database issue):D413 (2015) PMID 25378316

    IMGT(®), the international ImMunoGeneTics information system(®)(http://www.imgt.org) is the global reference in immunogenetics and immunoinformatics. By its creation in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), IMGT(®) marked the advent of immunoinformatics, which emerged...
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  2. IMGT®, the international ImMunoGeneTics information system® 25 years on.

    Nucleic Acids Research 43(Database issue):D413 (2015) PMID 25378316 PMCID PMC4383898

    IMGT(®), the international ImMunoGeneTics information system(®)(http://www.imgt.org) is the global reference in immunogenetics and immunoinformatics. By its creation in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), IMGT(®) marked the advent of immunoinformatics, which emerged...
  3. IMGT®, the international ImMunoGeneTics information system® 25 years on.

    Nucleic Acids Research 43(Database issue):D413 (2015) PMID 25378316

    IMGT(®), the international ImMunoGeneTics information system(®)(http://www.imgt.org) is the global reference in immunogenetics and immunoinformatics. By its creation in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), IMGT(®) marked the advent of immunoinformatics, which emerged...
    PDF not found
  4. Dedicator of cytokinesis 8–deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells

    Journal of Allergy and Clinical Immunology 134(6):1365 (2014)

    Background Dedicator of cytokinesis 8 (DOCK8) deficiency is typified by recurrent infections, increased serum IgE levels, eosinophilia, and a high incidence of allergic and autoimmune manifestations.
  5. Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells.

    Journal of Allergy and Clinical Immunology 134(6):1365 (2014) PMID 25218284 PMCID PMC4261031

    Dedicator of cytokinesis 8 (DOCK8) deficiency is typified by recurrent infections, increased serum IgE levels, eosinophilia, and a high incidence of allergic and autoimmune manifestations. We sought to determine the role of DOCK8 in the establishment and maintenance of human B-cell tolerance. Au...
  6. Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells.

    Journal of Allergy and Clinical Immunology 134(6):1365 (2014) PMID 25218284 PMCID PMC4261031

    Dedicator of cytokinesis 8 (DOCK8) deficiency is typified by recurrent infections, increased serum IgE levels, eosinophilia, and a high incidence of allergic and autoimmune manifestations. We sought to determine the role of DOCK8 in the establishment and maintenance of human B-cell tolerance. Au...
  7. Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells.

    Journal of Allergy and Clinical Immunology 134(6):1365 (2014) PMID 25218284 PMCID PMC4261031

    Dedicator of cytokinesis 8 (DOCK8) deficiency is typified by recurrent infections, increased serum IgE levels, eosinophilia, and a high incidence of allergic and autoimmune manifestations. We sought to determine the role of DOCK8 in the establishment and maintenance of human B-cell tolerance. Au...
  8. Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells.

    Journal of Allergy and Clinical Immunology 134(6):1365 (2014) PMID 25218284 PMCID PMC4261031

    Dedicator of cytokinesis 8 (DOCK8) deficiency is typified by recurrent infections, increased serum IgE levels, eosinophilia, and a high incidence of allergic and autoimmune manifestations. We sought to determine the role of DOCK8 in the establishment and maintenance of human B-cell tolerance. Au...
  9. Plasmacytoid dendritic cell depletion in DOCK8 deficiency: rescue of severe herpetic infections with IFN-α 2b therapy.

    Journal of Allergy and Clinical Immunology 133(6):1753 (2014) PMID 24767873 PMCID PMC4052613

  10. Plasmacytoid dendritic cell depletion in DOCK8 deficiency: rescue of severe herpetic infections with IFN-α 2b therapy.

    Journal of Allergy and Clinical Immunology 133(6):1753 (2014) PMID 24767873 PMCID PMC4052613

  11. DOCK8 deficient patients have a breakdown in peripheral B cell tolerance and defective regulatory T cells

    Journal of Allergy and Clinical Immunology (2014)

    Background Dedicator of Cytokinesis 8 (DOCK8) deficiency is typified by recurrent infections, elevated serum IgE levels, eosinophilia, and a high incidence of allergic and autoimmune manifestations.
  12. DOCK8 deficient patients have a breakdown in peripheral B cell tolerance and defective regulatory T cells

    Journal of Allergy and Clinical Immunology (2014)

    Background Dedicator of Cytokinesis 8 (DOCK8) deficiency is typified by recurrent infections, elevated serum IgE levels, eosinophilia, and a high incidence of allergic and autoimmune manifestations.
  13. DOCK8 deficient patients have a breakdown in peripheral B cell tolerance and defective regulatory T cells

    Journal of Allergy and Clinical Immunology (2014)

    Background Dedicator of Cytokinesis 8 (DOCK8) deficiency is typified by recurrent infections, elevated serum IgE levels, eosinophilia, and a high incidence of allergic and autoimmune manifestations.
  14. Flow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis.

    Clinical Immunology 150(2):220 (2014) PMID 24440647 PMCID PMC3924424

    DOCK8 deficiency is a primary immunodeficiency characterized by recurrent sinopulmonary infections, dermatitis with cutaneous infections, elevated serum IgE levels, eosinophilia, and a high incidence of food allergy. Given the seriousness of DOCK8 deficiency, it is important to recognize it earl...
  15. Flow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis

    Clinical Immunology 150(2):220 (2014)

    DOCK8 deficiency is a primary immunodeficiency characterized by recurrent sinopulmonary infections, dermatitis with cutaneous infections, elevated serum IgE levels, eosinophilia, and a high incidence of food allergy. Given the seriousness of DOCK8 deficiency, it is important to recogni...
  16. Flow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis.

    Clinical Immunology 150(2):220 (2014) PMID 24440647 PMCID PMC3924424

    DOCK8 deficiency is a primary immunodeficiency characterized by recurrent sinopulmonary infections, dermatitis with cutaneous infections, elevated serum IgE levels, eosinophilia, and a high incidence of food allergy. Given the seriousness of DOCK8 deficiency, it is important to recognize it earl...
  17. Flow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis

    Clinical Immunology 150(2):220 (2014) PMID 24440647 PMCID PMC3924424

    DOCK8 deficiency is a primary immunodeficiency characterized by recurrent sinopulmonary infections, dermatitis with cutaneous infections, elevated serum IgE levels, eosinophilia, and a high incidence of food allergy. Given the seriousness of DOCK8 deficiency, it is important to recogni...
  18. Flow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis.

    Clinical Immunology 150(2):220 (2014) PMID 24440647 PMCID PMC3924424

    DOCK8 deficiency is a primary immunodeficiency characterized by recurrent sinopulmonary infections, dermatitis with cutaneous infections, elevated serum IgE levels, eosinophilia, and a high incidence of food allergy. Given the seriousness of DOCK8 deficiency, it is important to recognize it earl...
  19. The intellectual disability of trisomy 21: differences in gene expression in a case series of patients with lower and higher IQ.

    European Journal of Human Genetics 21(11):1253 (2013) PMID 23422941 PMCID PMC3798834

    Trisomy 21 (T21), or Down syndrome (DS), is the most frequent and recognizable cause of intellectual disabilities. The level of disability, as evaluated by the intelligence quotient (IQ) test, varies considerably between patients independent of other factors. To determine the genetic or molecula...
  20. The intellectual disability of trisomy 21: differences in gene expression in a case series of patients with lower and higher IQ.

    European Journal of Human Genetics 21(11):1253 (2013) PMID 23422941 PMCID PMC3798834

    Trisomy 21 (T21), or Down syndrome (DS), is the most frequent and recognizable cause of intellectual disabilities. The level of disability, as evaluated by the intelligence quotient (IQ) test, varies considerably between patients independent of other factors. To determine the genetic or molecula...