Relaxation enhanced compressed sensing three-dimensional black-blood vessel wall MR imaging: Preliminary studies.
Magnetic Resonance Imaging 33(7):932 (2015)
In this study, we sought to investigate the feasibility of a new technique termed relaxation enhanced compressed sensing three-dimensional motion-sensitizing driven equilibrium prepared 3D rapid gradient echo sequence (RECS-3D MERGE).
The RECS-3D MERGE sequence consisted of a 3D MERGE sequence f...
A hydrophobic interaction chromatography strategy for purification of inactivated foot-and-mouth disease virus.
Protein Expression and Purification 113:23 (2015)
A purification scheme based on hydrophobic interaction chromatography was developed to separate inactivated foot-and-mouth disease virus (FMDV) from crude supernatant. About 92% recovery and 8.8-fold purification were achieved on Butyl Sepharose 4 FF. Further purification on Superdex 200 resulte...
Contribution of coated humic acids calculated through their surface coverage on nano iron oxides for ofloxacin and norfloxacin sorption.
Environmental Pollution 204:191 (2015)
Sorption of organic contaminants on organo-mineral complexes has been investigated extensively, but the sorption contribution of mineral particles was not properly addressed before calculating KOC, especially for ionic organic contaminants. We measured the surface coverage of a humic acid (HA) o...
A quantitative approach to developing Parkinsonian monkeys (Macaca fascicularis) with intracerebroventricular 1-methyl-4-phenylpyridinium injections.
Journal of Neuroscience Methods 251:99 (2015)
Non-human primate Parkinson's disease (PD) models are essential for PD research. The most extensively used PD monkey models are induced with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). However, the modeling processes of developing PD monkeys cannot be quantitatively controlled with MPTP...
The impact of rheumatoid arthritis on work capacity in Chinese patients: a cross-sectional study.
Rheumatology 54(8):1478 (2015)
To evaluate the impact of RA on work capacity and identify factors related to work capacity impairment in patients with RA.
A cross-sectional multicentre study was performed in 21 tertiary care hospitals across China. A consecutive sample of 846 patients with RA was recruited, of which 589 patie...
Transmitted Extended-Spectrum Extensively Drug-Resistant Tuberculosis in Beijing, China, with Discordant Whole-Genome Sequencing Analysis Results.
Journal of Clinical Microbiology 53(8):2781 (2015)
Drug resistance to tuberculosis remains a major public health threat. Here, we report two cases of extended-spectrum extensively drug-resistant (XXDR) tuberculosis showing resistance to most first- and second-line agents. The results of a correlation of whole-genome sequencing (WGS) and phenotyp...
Bioceramic microneedles with flexible and self-swelling substrate.
European Journal of Pharmaceutics and Biopharma... 94:404 (2015)
To reduce the effort required to penetrate the skin and optimize drug release profiles, bioceramic microneedle arrays with higher-aspect-ratio needles and a flexible and self-swelling substrate have been developed. Swelling of the substrate can assist in separating it from the needles and leave ...
Gold Nanorods Bioconjugates for Intracellular Delivery and Cancer Cell Apoptosis.
Journal of Laboratory Automation 20(4):418 (2015)
The aim of this study was to identify an improved delivery scheme for intracellular delivery and anticancer therapy. Novel gold nanorods (GNRs) bioconjugates were prepared by using GNRs as nonviral vectors conjugated with thiol-modified antisense oligodeoxynucleotides (ASODNs). We then investiga...
Growing trend of China's contribution to the field of spine: a 10-year survey of the literature.
European Spine Journal 24(8):1806 (2015)
China, as a rapidly developing country with the largest population including over 50,000 orthopaedic surgeons, has an increasing importance in the field of spine. However, the quantity and quality of research production in the field of spine in the major regions of China-Mainland China, Taiwan, ...
A practical and highly sensitive C3N4-TYR fluorescent probe for convenient detection of dopamine.
Nanoscale 7(28):12068 (2015)
The C3N4-tyrosinase (TYR) hybrid is a highly accurate, sensitive and simple fluorescent probe for the detection of dopamine (DOPA). Under optimized conditions, the relative fluorescence intensity of C3N4-TYR is proportional to the DOPA concentration in the range from 1 × 10(-3) to 3 × 10(-8) mol...
Divergent Synthesis of Imidazoles and Quinazolines via Pd(OAc)2-Catalyzed Annulation of N-Allylamidines.
Organic Letters 17(14):3434 (2015)
A Pd(OAc)2-catalyzed divergent synthesis of multisubstituted imidazoles and quinazolines from N-allylamidines has been developed. In the presence of oxidant O2 from air and/or a ligand and Pd(OAc)2, imidazoles were obtained. Nonetheless, under microwave (MW) irradiation in a sealed system, quina...
Influence of dissolved organic nitrogen on Ni bioavailability in Prorocentrum donghaiense and Skeletonema costatum.
Marine Pollution Bulletin 96(1-2):368 (2015)
Dissolved organic nitrogen (DON) is an important nutrient in the aquatic environment. This study examined the influence of DON addition on the adsorption, absorption, and distribution in macromolecular forms of environmentally deleterious trace metal (Ni) in Prorocentrum donghaiense and Skeleton...
Detection of structurally similar adulterants in botanical dietary supplements by thin-layer chromatography and surface enhanced Raman spectroscopy combined with two-dimensional correlation spectroscopy.
Analytica Chimica Acta 883:22 (2015)
Thin-layer chromatography (TLC) coupled with surface enhanced Raman spectroscopy (SERS) has been widely used for the study of various complex systems, especially for the detection of adulterants in botanical dietary supplements (BDS). However, this method is not sufficient to distinguish structu...
Clopidogrel With Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) Trial: One-Year Outcomes.
Circulation 132(1):40 (2015)
The Clopidogrel in High-risk patients with Acute Non-disabling Cerebrovascular Events (CHANCE) trial showed that the combined treatment of clopidogrel and aspirin decreases the 90-day risk of stroke without increasing hemorrhage in comparison with aspirin alone, but provided insufficient data to...
Sensitive detection of a serum biomarker based on peptide nucleic acid-coupled dual cycling reactions.
Analytica Chimica Acta 882:27 (2015)
Serum level of disease markers may provide important guidance for diagnosis and prognosis. In this work, a sensitive and specific method suitable for direct serum detection of biomarkers is developed based on peptide nucleic acid (PNA)-coupled DNA cycling reactions with dual amplification. In th...
Preoperative Serum Thyrotropin to Thyroglobulin Ratio Is Effective for Thyroid Nodule Evaluation in Euthyroid Patients.
Otolaryngology -- Head and Neck Surgery 153(1):15 (2015)
This study was designed to assess the efficiency of the serum thyrotropin to thyroglobulin ratio for thyroid nodule evaluation in euthyroid patients.
Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China.
Retrospective analysis was performed...
Comparative characterization of microRNAs in Schistosoma japonicum schistosomula from Wistar rats and BALB/c mice.
Parasitology Research 114(7):2639 (2015)
More than 40 kinds of mammals in China are known to be naturally infected with Schistosoma japonicum (S. japonicum) (Peng et al. Parasitol Res 106:967-76, 2010). Compared with permissive BALB/c mice, rats are less susceptible to S. japonicum infection and are considered to provide an unsuitable ...
Interferon-induced mechanosensing defects impede apoptotic cell clearance in lupus.
Journal of Clinical Investigation 125(7):2877 (2015)
Systemic lupus erythematosus (SLE) is a severe autoimmune disease that is associated with increased circulating apoptotic cell autoantigens (AC-Ags) as well as increased type I IFN signaling. Here, we describe a pathogenic mechanism in which follicular translocation of marginal zone (MZ) B cells...
Construction of an all-carbon quaternary stereocenter by organocatalytic enantioselective α-functionalization of α-substituted β-ketocarbonyls with electron deficient vinylarenes.
Chemical Communications 51(56):11221 (2015)
A chiral amine catalyzed enantioselective α-functionalization of α-substituted β-ketocarbonyls with electron-deficient vinylarenes has been developed to construct the dicarbonyl products with the formation of a chiral all-carbon quaternary stereocenter. The products can be used for the efficient...
Large-sensitive-area superconducting nanowire single-photon detector at 850 nm with high detection efficiency.
Optics Express 23(13):17301 (2015)
Satellite-ground quantum communication requires single-photon detectors of 850-nm wavelength with both high detection efficiency and large sensitive area. We developed superconducting nanowire single-photon detectors (SNSPDs) on one-dimensional photonic crystals, which acted as optical cavities ...