1. Carbon dots with high fluorescence quantum yield: the fluorescence originates from organic fluorophores.

    Nanoscale 8(30):14374 (2016) PMID 27426926

    In this contribution, we have shown that the organic fluorophores, 5-oxo-3,5-dihydro-2H-thiazolo [3,2-a] pyridine-3,7-dicarboxylic acid (TPDCA) and 5-oxo-3,5-dihydro-2H-thiazolo [3,2-a] pyridine-7-carboxylic acid (TPCA), are the main ingredients and fluorescence origins of N,S-CDs via systematic...
  2. Enhanced efficacy and anti-biofilm activity of novel nanoemulsions against skin burn wound multi-drug resistant MRSA infections.

    Nanomedicine: Nanotechnology, Biology and Medicine 12(6):1543 (2016) PMID 26961464

    Multi-drug resistant MRSA (methicillin-resistant Staphylococcus aureus) is a global problem for human health, especially skin burn wound patients. Therefore, we estimated the antibacterial and anti-biofilm activity of a chlorhexidine acetate nanoemulsion (CNE) by previously ourselves designed ag...
  3. A strategy for screening active lead compounds and functional compound combinations from herbal medicines based on pharmacophore filtering and knockout/knockin chromatography.

    Journal of chromatography. A 1456:176 (2016) PMID 27320377

    Screening and deciphering active natural products of herbal medicines are of great importance for modern drug discovery. In this study, a novel strategy was proposed to rapidly filter ineffective compounds and target the most potential leads. The aim is to answer the key question of what compone...
  4. Structured light enables biomimetic swimming and versatile locomotion of photoresponsive soft microrobots.

    Nature Materials 15(6):647 (2016) PMID 26878315

    Microorganisms move in challenging environments by periodic changes in body shape. In contrast, current artificial microrobots cannot actively deform, exhibiting at best passive bending under external fields. Here, by taking advantage of the wireless, scalable and spatiotemporally selective capa...
  5. The expression profile and prognostic value of SPINK1 in initially diagnosed bone metastatic prostate cancer.

    Prostate 76(9):823 (2016) PMID 27159572

    SPINK1 has been described to be mutually exclusively expressed in prostate cancer (PCa), but its expression profiles and the probable roles in bone metastatic PCa have not been thoroughly explored. Total of 155 biopsy specimens from initially diagnosed bone metastatic PCa were obtained between 2...
  6. [Immediate Inguinal Lymph Node Dissection Improves Survival in Patients of Penile Cancer].

    Sichuan da xue xue bao. Yi xue ban = Journal of... 47(3):371 (2016) PMID 27468483

    To investigate the clinical outcome of immediate inguinal lymph node dissection on the survival of the patients with penile carcinoma. A total of 67 patients of penile carcinoma whose inguinal lymph nodes (ILN) were initial clinically impalpable, received inguinal lymph node dissection (ILND) fr...
  7. Gene expression profiling of Ctr9-regulated transcriptome in ERα-positive breast cancer.

    Genomics Data 7:103 (2016) PMID 26981377 PMCID PMC4778656

    Ctr9, the key scaffold subunit in human RNA polymerase II associated factor complex (PAFc), has diverse functions in cells and has been implicated in human diseases. Recently, our study found that loss of Ctr9 led to apparent morphological change, decrease of proliferation, and reduced colony fo...
  8. Two approaches for treating upper thoracic spinal tuberculosis with neurological deficits in the elderly: A retrospective case-control study.

    Clinical Neurology and Neurosurgery 141:111 (2016) PMID 26773701

    The current study compared clinical outcomes of two diverse therapeutic strategies for upper thoracic (T1-4) spinal tuberculosis with neurological deficits in elderly patients. A retrospective analysis was performed on 18 cases undergoing single-stage posterior transpedicular decompression, debr...
  9. [Combined intravenous and intrathecal vancomycin in treatment of patients with intracranial infections after craniotomy].

    Zhonghua wei zhong bing ji jiu yi xue 28(2):169 (2016) PMID 26911951

    To explore the efficacy and safety of combined intravenous and intrathecal vancomycin in treatment of patients with intracranial infection after craniotomy. Clinical data of a total of 60 consecutive patients with intracranial infections after cranial operation admitted to Department of Neurosur...
  10. The pivotal role of malic enzyme in enhancing oil accumulation in green microalga Chlorella pyrenoidosa.

    Microbial Cell Factories 15(1):120 (2016) PMID 27387324 PMCID PMC4936009

    The fast growing photosynthetic microalgae have been widely used in aquaculture, food, health, and biofuels. Recent findings in the diatom has proposed a pivotal role of NADP-malic enzyme in generation of NADPH as an important supply of reducing power for fatty acid biosynthesis. To test the lip...
  11. 360-degree cervical spinal arthrodesis for treatment of pediatric cervical spinal tuberculosis with kyphosis.

    BMC Musculoskeletal Disorders 17(1):175 (2016) PMID 27108221 PMCID PMC4842264

    There is limited evidence to guide treatment for pediatric cervical spinal tuberculosis with kyphosis (PCSTK). This study retrospectively evaluates the safety, feasibility and efficacy of 360-degree arthrodesis combined with anterior debridement and decompression for treating PCSTK, while simult...
  12. A novel nitro-dexamethasone inhibits agr system activity and improves therapeutic effects in MRSA sepsis models without antibiotics.

    Scientific reports 6:20307 (2016) PMID 26839286 PMCID PMC4738243

    Methicillin-resistant Staphylococcus aureus (MRSA) sepsis is a life-threatening medical condition that involves systemic inflammation throughout the body. Glucocorticoids are widely used in combination with antibiotics in the treatment of MRSA sepsis to fight the overwhelming inflammation. Here,...
  13. Protective efficacy of the chimeric Staphylococcus aureus vaccine candidate IC in sepsis and pneumonia models.

    Scientific reports 6:20929 (2016) PMID 26865417 PMCID PMC4750066

    Staphylococcus aureus causes serious sepsis and necrotic pneumonia worldwide. Due to the spread of multidrug-resistant strains, developing an effective vaccine is the most promising method for combating S. aureus infection. In this study, based on the immune-dominant areas of the iron surface de...
  14. [The comparison of the 1992 and 2012 Atlanta classifications for assessing disease severity in patients with acute pancreatitis].

    Chinese Journal of Internal Medicine 55(1):21 (2016) PMID 26796648

    To compare the discrepancy between the new(2012) and the old (1992) Atlanta classification criteria for defining severity, organ failure and local complications in patients with acute pancreatitis (AP). Demographic, clinical and laboratory data of 2,305 consecutive AP patients with onset less th...
  15. Free-form Light Actuators - Fabrication and Control of Actuation in Microscopic Scale.

    Journal of Visualized Experiments (111) (2016) PMID 27285398 PMCID PMC4942173

    Liquid crystalline elastomers (LCEs) are smart materials capable of reversible shape-change in response to external stimuli, and have attracted researchers' attention in many fields. Most of the studies focused on macroscopic LCE structures (films, fibers) and their miniaturization is still in i...
  16. Immunisation With Immunodominant Linear B Cell Epitopes Vaccine of Manganese Transport Protein C Confers Protection against Staphylococcus aureus Infection.

    PLoS ONE 11(2):e0149638 (2016) PMID 26895191 PMCID PMC4764517

    Vaccination strategies for Staphylococcus aureus, particularly methicillin-resistant S. aureus (MRSA) infections have attracted much research attention. Recent efforts have been made to select manganese transport protein C, or manganese binding surface lipoprotein C (MntC), which is a metal ion ...
  17. Different lasers in the treatment of benign prostatic hyperplasia: a network meta-analysis.

    Scientific reports 6:23503 (2016) PMID 27009501 PMCID PMC4806333

    All available surgical treatments for benign prostatic hyperplasia (BPH) have their individual advantages or disadvantages. However, the lack of head-to-head studies comparing different surgeries makes it unavailable to conduct direct analysis. To compare the efficacy and safety among different ...
  18. Prophylactic Antibiotics in Prostate Biopsy: A Meta-Analysis Based on Randomized Controlled Trials.

    Surgical Infections 16(6):733 (2015) PMID 26325245

    Despite frequent use of prophylactic antibiotics for patients undergoing transrectal prostate biopsy (TRPB), the incidences of urinary tract infection (UTI) and bacteria resistance are increasing. The aim of this study is to evaluate the current regimen of antimicrobial prophylaxis in TRPB. A sy...
  19. Engineering optical properties of metal/porous anodic alumina films for refractometric sensing

    Applied Surface Science 355:139 (2015)

  20. Halo traction, single-segment circumferential fixation treating cervical tubercular spondylitis with kyphosis.

    Clinical Neurology and Neurosurgery 138:59 (2015) PMID 26280284

    To evaluate the clinical efficacy and feasibility of twenty patients with cervical tubercular spondylitis with kyphosis (CTSK) treated by halo traction, single-segment circumferential instrumented fusion combined anterior debridement, decompression and bone grafting. Retrospective review of data...