1. Interregional Coevolution Analysis Revealing Functional and Structural Interrelatedness between Different Genomic Regions in Human Mastadenovirus D.

    Journal of Virology 89(12):6209 (2015) PMID 25833048 PMCID PMC4474320

    Human mastadenovirus D (HAdV-D) is exceptionally rich in type among the seven human adenovirus species. This feature is attributed to frequent intertypic recombination events that have reshuffled orthologous genomic regions between different HAdV-D types. However, this trend appears to be parado...
  2. Intertypic modular exchanges of genomic segments by homologous recombination at universally conserved segments in human adenovirus species D.

    Gene 547(1):10 (2014) PMID 24726548

    Human adenovirus species D (HAdV-D), which is composed of clinically and epidemiologically important pathogens worldwide, contains more taxonomic "types" than any other species of the genus Mastadenovirus, although the mechanisms accounting for the high level of diversity remain to be disclosed....
  3. A novel complex recombinant form of type 48-related human adenovirus species D isolated in Japan.

    Japanese Journal of Infectious Diseases 67(4):282 (2014) PMID 25056074

    Recently, new genotypes of human adenoviruses (HAdVs) have been reported and many of them have been found to be recombinant forms of different known types of HAdV species D (HAdV-D). The objective of this study was to document the evolutionary features of a novel isolate (HAdV_Chiba_E086/2012) o...
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  4. A novel complex recombinant form of type 48-related human adenovirus species D isolated in Japan.

    Japanese Journal of Infectious Diseases 67(4):282 (2014) PMID 25056074

    Recently, new genotypes of human adenoviruses (HAdVs) have been reported and many of them have been found to be recombinant forms of different known types of HAdV species D (HAdV-D). The objective of this study was to document the evolutionary features of a novel isolate (HAdV_Chiba_E086/2012) o...
    PDF not found
  5. Contribution of antimicrobial stewardship programs to reduction of antimicrobial therapy costs in community hospital with 429 Beds --before-after comparative two-year trial in Japan.

    Journal of pharmaceutical policy and practice 7(1):10 (2014) PMID 25136450 PMCID PMC4133084

    Do antimicrobial stewardship programs (ASPs) contribute to reduction of antimicrobial therapy costs in Japanese community hospitals? To answer this health economic question, a before-after comparative two-year trial in a community hospital in the country was designed. The study was conducted at ...
  6. Contribution of antimicrobial stewardship programs to reduction of antimicrobial therapy costs in community hospital with 429 Beds --before-after comparative two-year trial in Japan.

    Journal of pharmaceutical policy and practice 7(1):10 (2014) PMID 25136450 PMCID PMC4133084

    Do antimicrobial stewardship programs (ASPs) contribute to reduction of antimicrobial therapy costs in Japanese community hospitals? To answer this health economic question, a before-after comparative two-year trial in a community hospital in the country was designed. The study was conducted at ...
  7. A novel complex recombinant form of type 48-related human adenovirus species D isolated in Japan.

    Japanese Journal of Infectious Diseases 67(4):282 (2014) PMID 25056074

    Recently, new genotypes of human adenoviruses (HAdVs) have been reported and many of them have been found to be recombinant forms of different known types of HAdV species D (HAdV-D). The objective of this study was to document the evolutionary features of a novel isolate (HAdV_Chiba_E086/2012) o...
    PDF not found
  8. [Bioinformatics on new human adenoviruses causing nosocomial infection].

    Nippon Ganka Gakkai zasshi 117(9):721 (2013) PMID 24261186

    Human adenovirus (HAdV) causing epidemic keratoconjunctivitis is limited to D and E species. Recent progress in bioinformatics revealed that these viruses attach to the host with fibers, infiltrate the host cells via RGD (Arg-Gly-Asp) motif of penton base, and reveal their serological reaction b...
  9. [Bioinformatics on new human adenoviruses causing nosocomial infection].

    Nippon Ganka Gakkai zasshi 117(9):721 (2013) PMID 24261186

    Human adenovirus (HAdV) causing epidemic keratoconjunctivitis is limited to D and E species. Recent progress in bioinformatics revealed that these viruses attach to the host with fibers, infiltrate the host cells via RGD (Arg-Gly-Asp) motif of penton base, and reveal their serological reaction b...
  10. Identification of contamination in the American type culture collection stock of human adenovirus type 8 by whole-genome sequencing.

    Journal of Virology 87(2):1285 (2013) PMID 23152510 PMCID PMC3554079

  11. Identification of contamination in the American type culture collection stock of human adenovirus type 8 by whole-genome sequencing.

    Journal of Virology 87(2):1285 (2013) PMID 23152510 PMCID PMC3554079

  12. In silico and in vivo identification of the intermediate filament vimentin that is downregulated downstream of Brachyury during Xenopus embryogenesis.

    Gene 491(2):232 (2012) PMID 21963995

    Brachyury, a member of the T-box transcription family, has been suggested to be essential for morphogenetic movements in various processes of animal development. However, little is known about its critical transcriptional targets. In order to identify targets of Brachyury and understand the mole...
  13. Comparative genome analysis of three eukaryotic parasites with differing abilities to transform leukocytes reveals key mediators of Theileria-induced leukocyte transformation.

    mBio 3(5):e00204 (2012) PMID 22951932 PMCID PMC3445966

    We sequenced the genome of Theileria orientalis, a tick-borne apicomplexan protozoan parasite of cattle. The focus of this study was a comparative genome analysis of T. orientalis relative to other highly pathogenic Theileria species, T. parva and T. annulata. T. parva and T. annulata induce tra...
  14. In silico and in vivo identification of the intermediate filament vimentin that is downregulated downstream of Brachyury duringXenopusembryogenesis

    Gene 491(2):232 (2012)

    Brachyury, a member of the T-box transcription family, has been suggested to be essential for morphogenetic movements in various processes of animal development. However, little is known about its critical transcriptional targets. In order to identify targets of Brachyury and understand the...
  15. In silico and in vivo identification of the intermediate filament vimentin that is downregulated downstream of Brachyury duringXenopusembryogenesis

    Gene 491(2):232 (2012) PMID 21963995

    Brachyury, a member of the T-box transcription family, has been suggested to be essential for morphogenetic movements in various processes of animal development. However, little is known about its critical transcriptional targets. In order to identify targets of Brachyury and understand the...
  16. In silico and in vivo identification of the intermediate filament vimentin that is downregulated downstream of Brachyury duringXenopusembryogenesis

    Gene 491(2):232 (2012) PMID 21963995

    Brachyury, a member of the T-box transcription family, has been suggested to be essential for morphogenetic movements in various processes of animal development. However, little is known about its critical transcriptional targets. In order to identify targets of Brachyury and understand the...
  17. Recombination analysis of intermediate human adenovirus type 53 in Japan by complete genome sequence.

    Journal of General Virology 92(Pt 6):1251 (2011) PMID 21402595

    Human adenovirus type 53 (HAdV-53) has commonly been detected in samples from epidemic keratoconjunctivitis (EKC) patients in Japan since 1996. HAdV-53 is an intermediate virus, containing hexon-chimeric, penton base and fiber structures similar to HAdV-22 and -37, HAdV-37 and HAdV-8, respective...
  18. Recombination analysis of intermediate human adenovirus type 53 in Japan by complete genome sequence.

    Journal of General Virology 92(Pt 6):1251 (2011) PMID 21402595

    Human adenovirus type 53 (HAdV-53) has commonly been detected in samples from epidemic keratoconjunctivitis (EKC) patients in Japan since 1996. HAdV-53 is an intermediate virus, containing hexon-chimeric, penton base and fiber structures similar to HAdV-22 and -37, HAdV-37 and HAdV-8, respective...
  19. Complete genome analysis of a novel intertypic recombinant human adenovirus causing epidemic keratoconjunctivitis in Japan.

    Journal of Clinical Microbiology 49(2):484 (2011) PMID 21147954 PMCID PMC3043511

    For 4 months from September 2008, 102 conjunctival swab specimens were collected for surveillance purposes from patients across Japan suspected of having epidemic keratoconjunctivitis (EKC). Human adenovirus (HAdV) DNA was detected in 61 samples by PCR, though the HAdV type for 6 of the PCR-posi...
  20. Complete genome analysis of a novel intertypic recombinant human adenovirus causing epidemic keratoconjunctivitis in Japan.

    Journal of Clinical Microbiology 49(2):484 (2011) PMID 21147954 PMCID PMC3043511

    For 4 months from September 2008, 102 conjunctival swab specimens were collected for surveillance purposes from patients across Japan suspected of having epidemic keratoconjunctivitis (EKC). Human adenovirus (HAdV) DNA was detected in 61 samples by PCR, though the HAdV type for 6 of the PCR-posi...