1. Donepezil treatment in ethnically diverse patients with Alzheimer disease.

    American Journal of Geriatric Psychiatry 23(4):384 (2015) PMID 25747405

    To compare the outcome of donepezil treatment in ethnically diverse Alzheimer disease (AD) patients with ethnically diverse AD patients who did not receive donepezil. Patients meeting NINCDS-ADRA criteria for probable or possible AD from a consortium of California sites were systematically follo...
  2. Donepezil Treatment in Ethnically Diverse Patients with Alzheimer Disease

    American Journal of Geriatric Psychiatry 23(4):384 (2015) PMID 25747405

    Objective To compare the outcome of donepezil treatment in ethnically diverse Alzheimer disease (AD) patients with ethnically diverse AD patients who did not receive donepezil.
  3. Increased Prevalence of Sleep Disordered Breathing in Older Veterans with PTSD

    American Journal of Geriatric Psychiatry 23(3):S180 (2015)

  4. The impact of depression on Veterans with PTSD and traumatic brain injury: A diffusion tensor imaging study.

    Biological Psychology 105:20 (2015) PMID 25559772

    A significant proportion of military personnel deployed in support of Operation Enduring Freedom and Operation Iraqi Freedom were exposed to war-zone events associated with traumatic brain injury (TBI), depression (DEP) and posttraumatic stress disorder (PTSD). The co-occurrence of TBI, PTSD and...
  5. Nocturia reported in nightly sleep diaries: common occurrence with significant implications?

    Health Psychology 33(11):1362 (2014) PMID 24245840 PMCID PMC4119089

    Nocturia (nocturnal awakenings associated with urination) is so common a nocturnal behavior that its association with poor sleep is often overlooked. This study examined nocturia and its potential role in poor sleep by examining reported nightly awakenings and associated bathroom trips. Sleep di...
  6. Nocturia reported in nightly sleep diaries: common occurrence with significant implications?

    Health Psychology 33(11):1362 (2014) PMID 24245840 PMCID PMC4119089

    Nocturia (nocturnal awakenings associated with urination) is so common a nocturnal behavior that its association with poor sleep is often overlooked. This study examined nocturia and its potential role in poor sleep by examining reported nightly awakenings and associated bathroom trips. Sleep di...
  7. Effects of body mass index-related disorders on cognition: preliminary results.

    Diabetes Metabolic Syndrome and Obesity Targets... 7:145 (2014) PMID 24855383 PMCID PMC4020904

    Well-known risk factors for cognitive impairment are also associated with obesity. Research has highlighted genetic risk factors for obesity, yet the relationship of those risk factors with cognitive impairment is unknown. The objective of this study was to determine the associations between cog...
  8. Higher Landing Accuracy in Expert Pilots is Associated with Lower Activity in the Caudate Nucleus.

    PLoS ONE 9(11):e112607 (2014) PMID 25426935 PMCID PMC4245093

    The most common lethal accidents in General Aviation are caused by improperly executed landing approaches in which a pilot descends below the minimum safe altitude without proper visual references. To understand how expertise might reduce such erroneous decision-making, we examined relevant neur...
  9. Higher landing accuracy in expert pilots is associated with lower activity in the caudate nucleus.

    PLoS ONE 9(11):e112607 (2014) PMID 25426935 PMCID PMC4245093

    The most common lethal accidents in General Aviation are caused by improperly executed landing approaches in which a pilot descends below the minimum safe altitude without proper visual references. To understand how expertise might reduce such erroneous decision-making, we examined relevant neur...
  10. Longitudinal assessment of sleep disordered breathing in Vietnam veterans with post-traumatic stress disorder.

    Nature and Science of Sleep 6:123 (2014) PMID 25378962 PMCID PMC4219637

    Previous work has demonstrated the relatively high prevalence of risk factors for cognitive impairment, such as sleep disordered breathing (SDB) and obesity, in Vietnam War era veterans with post-traumatic stress disorder (PTSD). No data are currently available on the longitudinal stability of S...
  11. Longitudinal assessment of sleep disordered breathing in Vietnam veterans with post-traumatic stress disorder.

    Nature and Science of Sleep 6:123 (2014) PMID 25378962 PMCID PMC4219637

    Previous work has demonstrated the relatively high prevalence of risk factors for cognitive impairment, such as sleep disordered breathing (SDB) and obesity, in Vietnam War era veterans with post-traumatic stress disorder (PTSD). No data are currently available on the longitudinal stability of S...
  12. Higher landing accuracy in expert pilots is associated with lower activity in the caudate nucleus.

    PLoS ONE 9(11):e112607 (2014) PMID 25426935 PMCID PMC4245093

    The most common lethal accidents in General Aviation are caused by improperly executed landing approaches in which a pilot descends below the minimum safe altitude without proper visual references. To understand how expertise might reduce such erroneous decision-making, we examined relevant neur...
  13. Effects of body mass index-related disorders on cognition: preliminary results.

    Diabetes Metabolic Syndrome and Obesity Targets... 7:145 (2014) PMID 24855383 PMCID PMC4020904

    Well-known risk factors for cognitive impairment are also associated with obesity. Research has highlighted genetic risk factors for obesity, yet the relationship of those risk factors with cognitive impairment is unknown. The objective of this study was to determine the associations between cog...
  14. Phenotyping apathy in individuals with Alzheimer disease using functional principal component analysis.

    American Journal of Geriatric Psychiatry 21(4):391 (2013) PMID 23498386 PMCID PMC3603283

    To determine if there is a specific pattern of gross motor activity associated with apathy in individuals with Alzheimer disease (AD). Examination of ad libitum 24-hour ambulatory gross motor activity patterns. Community-dwelling, outpatient. Ninety-two individuals with AD, 35 of whom had apathy...
  15. Nocturia compounds nocturnal wakefulness in older individuals with insomnia.

    Journal of clinical sleep medicine : JCSM : off... 9(3):259 (2013) PMID 23493881 PMCID PMC3578689

    To determine the impact of nocturia on objective measures of sleep in older individuals with insomnia. The sleep and toileting patterns of a group of community-dwelling older men (n = 55, aged 64.3 ± 7.52 years) and women (n = 92, aged 62.5 ± 6.73 years) with insomnia were studied for two weeks ...
  16. Nocturia compounds nocturnal wakefulness in older individuals with insomnia.

    Journal of clinical sleep medicine : JCSM : off... 9(3):259 (2013) PMID 23493881 PMCID PMC3578689

    To determine the impact of nocturia on objective measures of sleep in older individuals with insomnia. The sleep and toileting patterns of a group of community-dwelling older men (n = 55, aged 64.3 ± 7.52 years) and women (n = 92, aged 62.5 ± 6.73 years) with insomnia were studied for two weeks ...
  17. Memantine is associated with longer survival than donepezil in a Veterans Affairs prescription database, 1997 to 2008.

    Journal of Alzheimer's Disease 36(4):791 (2013) PMID 23703151

    Alzheimer's disease (AD) shortens life-expectancy, but the effects of pharmacological treatments for this disorder on mortality have not been studied. We compared two commonly prescribed medications, donepezil and memantine, with respect to the length of survival of veterans presumed to have AD....
  18. Memantine is associated with longer survival than donepezil in a Veterans Affairs prescription database, 1997 to 2008.

    Journal of Alzheimer's Disease 36(4):791 (2013) PMID 23703151

    Alzheimer's disease (AD) shortens life-expectancy, but the effects of pharmacological treatments for this disorder on mortality have not been studied. We compared two commonly prescribed medications, donepezil and memantine, with respect to the length of survival of veterans presumed to have AD....
  19. Modeling the effects of obstructive sleep apnea and hypertension in Vietnam veterans with PTSD.

    Sleep and Breathing 16(4):1201 (2012) PMID 22193972

    The present work aimed to extend models suggesting that obstructive sleep apnea (OSA) is associated with worse cognitive performance in community-dwelling older adults. We hypothesized that in addition to indices of OSA severity, hypertension is associated with worse cognitive performance in suc...
  20. Modeling the effects of obstructive sleep apnea and hypertension in Vietnam veterans with PTSD.

    Sleep and Breathing 16(4):1201 (2012) PMID 22193972

    The present work aimed to extend models suggesting that obstructive sleep apnea (OSA) is associated with worse cognitive performance in community-dwelling older adults. We hypothesized that in addition to indices of OSA severity, hypertension is associated with worse cognitive performance in suc...