1. Drosophila Sugar Receptors in Sweet Taste Perception, Olfaction, and Internal Nutrient Sensing

    Current Biology 25(5):621 (2015) PMID 25702577

    Identification of nutritious compounds is dependent on expression of specific taste receptors in appropriate taste-cell types [1]. In contrast to mammals, which rely on a single, broadly tuned heterodimeric sugar receptor [2], the Drosophila genome harbors a small subfamily of eight, c...
  2. Drosophila sugar receptors in sweet taste perception, olfaction, and internal nutrient sensing.

    Current Biology 25(5):621 (2015) PMID 25702577

    Identification of nutritious compounds is dependent on expression of specific taste receptors in appropriate taste-cell types [1]. In contrast to mammals, which rely on a single, broadly tuned heterodimeric sugar receptor [2], the Drosophila genome harbors a small subfamily of eight, closely rel...
  3. A genetic tool kit for cellular and behavioral analyses of insect sugar receptors.

    Fly 8(4):189 (2014) PMID 25984594

    Arthropods employ a large family of up to 100 putative taste or gustatory receptors (Grs) for the recognition of a wide range of non-volatile chemicals. In Drosophila melanogaster, a small subfamily of 8 Gr genes is thought to mediate the detection of sugars, the fly's major nutritional source. ...
  4. The molecular basis of sugar sensing in Drosophila larvae.

    Current Biology 23(15):1466 (2013) PMID 23850280 PMCID PMC4294765

    Evaluation of food chemicals is essential to make appropriate feeding decisions. The molecular genetic analysis of Gustatory receptor (Gr) genes and the characterization of the neural circuits that they engage has led to a broad understanding of taste perception in adult Drosophila [1, 2]. For e...
  5. The molecular basis of sugar sensing in Drosophila larvae.

    Current Biology 23(15):1466 (2013) PMID 23850280

    Evaluation of food chemicals is essential to make appropriate feeding decisions. The molecular genetic analysis of Gustatory receptor (Gr) genes and the characterization of the neural circuits that they engage has led to a broad understanding of taste perception in adult Drosophila [1, 2]. For e...
  6. The Molecular Basis of Sugar Sensing inDrosophilaLarvae

    Current Biology 23(15):1466 (2013)

    Evaluation of food chemicals is essential to make appropriate feeding decisions. The molecular genetic analysis of Gustatory receptor (Gr) genes and the characterization of the neural circuits that they engage has led to a broad understanding of taste perception in adult Drosophila [1,...
  7. The Molecular Basis of Sugar Sensing in Drosophila Larvae

    Current Biology 23(15):1466 (2013) PMID 23850280 PMCID PMC4294765

    Evaluation of food chemicals is essential to make appropriate feeding decisions. The molecular genetic analysis of Gustatory receptor (Gr) genes and the characterization of the neural circuits that they engage has led to a broad understanding of taste perception in adult Drosophila [1,...
  8. The molecular basis of sugar sensing in Drosophila larvae.

    Current Biology 23(15):1466 (2013) PMID 23850280 PMCID PMC4294765

    Evaluation of food chemicals is essential to make appropriate feeding decisions. The molecular genetic analysis of Gustatory receptor (Gr) genes and the characterization of the neural circuits that they engage has led to a broad understanding of taste perception in adult Drosophila [1, 2]. For e...
  9. Identification of a Drosophila glucose receptor using Ca2+ imaging of single chemosensory neurons.

    PLoS ONE 8(2):e56304 (2013) PMID 23418550 PMCID PMC3571953

    Evaluation of food compounds by chemosensory cells is essential for animals to make appropriate feeding decisions. In the fruit fly Drosophila melanogaster, structurally diverse chemicals are detected by multimeric receptors composed of members of a large family of Gustatory receptor (Gr) protei...
  10. Identification of a Drosophila glucose receptor using Ca2+ imaging of single chemosensory neurons.

    PLoS ONE 8(2):e56304 (2013) PMID 23418550 PMCID PMC3571953

    Evaluation of food compounds by chemosensory cells is essential for animals to make appropriate feeding decisions. In the fruit fly Drosophila melanogaster, structurally diverse chemicals are detected by multimeric receptors composed of members of a large family of Gustatory receptor (Gr) protei...
  11. A Fructose Receptor Functions as a Nutrient Sensor in theDrosophilaBrain

    Cell 151(5):1113 (2012) PMID 23178127 PMCID PMC3509419

    Internal nutrient sensors play important roles in feeding behavior, yet their molecular structure and mechanism of action are poorly understood. Using Ca2+ imaging and behavioral assays, we show that the gustatory receptor 43a (Gr43a) functions as a narrowly tuned fructose receptor in ...
  12. A Fructose Receptor Functions as a Nutrient Sensor in the Drosophila Brain

    Cell 151(5):1113 (2012)

    Internal nutrient sensors play important roles in feeding behavior, yet their molecular structure and mechanism of action are poorly understood. Using Ca2+ imaging and behavioral assays, we show that the gustatory receptor 43a (Gr43a) functions as a narrowly tuned fructose receptor in ...
  13. A fructose receptor functions as a nutrient sensor in the Drosophila brain.

    Cell 151(5):1113 (2012) PMID 23178127 PMCID PMC3509419

    Internal nutrient sensors play important roles in feeding behavior, yet their molecular structure and mechanism of action are poorly understood. Using Ca(2+) imaging and behavioral assays, we show that the gustatory receptor 43a (Gr43a) functions as a narrowly tuned fructose receptor in taste ne...
  14. Sugar Receptors in Drosophila

    Current Biology 17(20):1809 (2007)

    The detection and discrimination of chemical compounds in potential foods are essential sensory processes when animals feed. The fruit fly Drosophila melanogaster employs 68 different gustatory receptors (GRs) for the detection of mostly nonvolatile chemicals that include sugars, a div...
  15. Sugar receptors in Drosophila.

    Current Biology 17(20):1809 (2007) PMID 17919910 PMCID PMC2078200

    The detection and discrimination of chemical compounds in potential foods are essential sensory processes when animals feed. The fruit fly Drosophila melanogaster employs 68 different gustatory receptors (GRs) for the detection of mostly nonvolatile chemicals that include sugars, a diverse group...
  16. Sugar receptors in Drosophila.

    Current Biology 17(20):1809 (2007) PMID 17919910 PMCID PMC2078200

    The detection and discrimination of chemical compounds in potential foods are essential sensory processes when animals feed. The fruit fly Drosophila melanogaster employs 68 different gustatory receptors (GRs) for the detection of mostly nonvolatile chemicals that include sugars, a diverse group...
  17. Sugar Receptors inDrosophila

    Current Biology 17(20):1809 (2007)

    The detection and discrimination of chemical compounds in potential foods are essential sensory processes when animals feed. The fruit fly Drosophila melanogaster employs 68 different gustatory receptors (GRs) for the detection of mostly nonvolatile chemicals that include sugars, a div...