1. Mitochondria-Targeted Antioxidant Peptide SS31 Protects Cultured Human Lens Epithelial Cells against Oxidative Stress.

    Current Eye Research 40(8):822 (2015) PMID 25310141

    To investigate the effects of the mitochondria-targeted peptide, SS31, on cultured human lens epithelial cells (HLECs) under conditions of oxidative stress. Optimal concentrations of SS31 were determined by MTT assay. HLEB-3 cells were first treated with SS31 for 2 h and then with 500 µM t-BHP f...
  2. Dihydromyricetin improves skeletal muscle insulin resistance by inducing autophagy via the AMPK signaling pathway.

    Molecular and Cellular Endocrinology 409:92 (2015) PMID 25797177

    Skeletal muscle insulin resistance (SMIR) plays an important role in the pathogenesis of type 2 diabetes. Dihydromyricetin (DHM), a natural flavonoid, exerts various bioactivities including anti-oxidative and hepatoprotective effects. Herein, we intended to determine the effect of DHM on SMIR an...
  3. Coumarin-based ‘turn-off’ fluorescent chemosensor with high selectivity for Cu2+ in aqueous solution

    Journal of Molecular Structure 1091:133 (2015)

    Chemosensor 1 was synthesized and exhibited highly selective and sensitive fluorescence sensing ability for Cu2+ over other metal ions in aqueous media. The fluorescence quenching response of 1 for Cu2+ indicated that 1 can be used as “turn-off” fluorescent chemosensor to selectively d...
  4. Coumarin-based ‘turn-off’ fluorescent chemosensor with high selectivity for Cu2+ in aqueous solution

    Journal of Molecular Structure 1091:133 (2015)

    Chemosensor 1 was synthesized and exhibited highly selective and sensitive fluorescence sensing ability for Cu2+ over other metal ions in aqueous media. The fluorescence quenching response of 1 for Cu2+ indicated that 1 can be used as “turn-off” fluorescent chemosensor to selectively d...
  5. Rapid Characterization and Identification of Flavonoids in Radix Astragali by Ultra-High-Pressure Liquid Chromatography Coupled with Linear Ion Trap-Orbitrap Mass Spectrometry.

    Journal of Chromatographic Science 53(6):945 (2015) PMID 25501118

    A simple and effective method was established for separation and characterization of flavonoid constituents in Radix Astragali (RA) by combination of ultra-high-pressure liquid chromatography with LTQ-Orbitrap tandem mass spectrometry (u-HPLC-LTQ-Orbitrap-MS(n)). For three major structural types...
  6. An Insertion/Deletion Polymorphism at miRNA-122 Binding Site in the IL1A Is Associated with a Reduced Risk of Cervical Squamous Cell Carcinoma.

    Genetic Testing and Molecular Biomarkers 19(6):331 (2015) PMID 25955681

    Previous studies have shown that miRNA plays a key role in cervical carcinogenesis. Interleukin (IL)-1α can promote tumor growth, invasion, migration, and angiogenesis. An insertion/deletion polymorphism (rs3783553) in the IL1A 3' untranslated region may disrupt a binding site for miR-122 and mi...
  7. Responses of soil acid phosphatase and beta-glucosidase to nitrogen and phosphorus addition in two subtropical forests in southern China

    European Journal of Soil Biology 68:77 (2015)

    Elevated nitrogen (N) deposition has dramatically altered soil phosphorus (P) and carbon (C) cycles in forests and altered extracellular enzyme activity. However, the effects of N addition and the interactive effects of combined N and P additions on soil enzyme (e.g. phosphatase and gl...
  8. Changes in lactate content and monocarboxylate transporter 2 expression in Aβ25-35-treated rat model of Alzheimer's disease.

    Neurological Sciences 36(6):871 (2015) PMID 25647291

    Decreased brain energy metabolism is correlated with cognitive impairment in Alzheimer's disease (AD). Accumulating evidence indicates that lactate and monocarboxylate transporters (MCTs) participate in brain energy metabolism. To date, changes in lactate level and expression of MCTs in AD remai...
  9. Identification of polycyclic aromatic hydrocarbons in soils in Taizhou, East China.

    Environmental Geochemistry and Health 37(3):429 (2015) PMID 25416074

    Polycyclic aromatic hydrocarbons (PAHs) and their hazards in surface soil (n = 92) were investigated in Taizhou, China, which is an area in East China famous for production and exporting of rice. Total concentrations of PAHs in soils ranged from 2.3 × 10(1) to 7.6 × 10(2) with a mean of 1.8 × 10...
  10. XRCC1 and ERCC1 polymorphisms are related to susceptibility and survival of colorectal cancer in the Chinese population.

    Mutagenesis 30(3):441 (2015) PMID 25690281

    Excision repair cross complementing group 1 (ERCC1) and X-ray repair cross-complementing groups 1 (XRCC1) are DNA repair enzymes. Polymorphisms in DNA repair genes may be important factors affecting cancer susceptibility, prognosis and therapy outcome. The purpose of this study was to investigat...
  11. Urbanization in China changes the composition and main sources of wet inorganic nitrogen deposition.

    Environmental Science and Pollution Research In... 22(9):6526 (2015) PMID 25529490

    Nowadays, nitrogen (N) deposition has become a growing global concern due to urbanization activities increasing the large amount of reactive N in the atmosphere. However, it remains unclear whether urbanization affects the composition and main sources of N deposition in rapidly urbanizing areas ...
  12. Homologous HOmologous Black-Bright-blood and flexible Interleaved imaging sequence (HOBBI) for dynamic contrast-enhanced MRI of the vessel wall.

    Magnetic Resonance in Medicine 73(5):1754 (2015) PMID 24805922

    To present a HOmologous Black-Bright-blood and flexible Interleaved imaging (HOBBI) sequence for dynamic contrast-enhanced magnetic resonance imaging (MRI) of the vessel wall. A HOBBI sequence is proposed to acquire high-spatial-resolution black-blood and high-temporal-resolution bright-blood dy...
  13. Divergent responses of soil buffering capacity to long-term N deposition in three typical tropical forests with different land-use history.

    Environmental Science & Technology 49(7):4072 (2015) PMID 25741588

    Elevated anthropogenic nitrogen (N) deposition has become an important driver of soil acidification at both regional and global scales. It remains unclear, however, how long-term N deposition affects soil buffering capacity in tropical forest ecosystems and in ecosystems of contrasting land-use ...
  14. Identification and characterization of the NMDA receptor and its role in regulating reproduction in the cockroach Diploptera punctata.

    Journal of Experimental Biology 218(Pt 7):983 (2015) PMID 25657209

    The NMDA receptor (NMDAR) plays important roles in excitatory neurotransmission and in the regulation of reproduction in mammals. NMDAR in insects comprises two subunits, NR1 and NR2. In this study, we identified two NR1 paralogs and eleven NR2 alternatively spliced variants in the cockroach Dip...
  15. Internalization of aquaporin-4 after collagenase-induced intracerebral hemorrhage.

    Anatomical Record. Part A: Advances in Integrat... 298(3):554 (2015) PMID 25257965

    Brain edema formation following intracerebral hemorrhage (ICH) appears to be related with aquaporin-4 (AQP4), which is critically involved in brain volume homeostasis and water balance. Despite its importance, the regulation of AQP4 expression involved in transmembrane water movements still rema...
  16. Alteration of Gene Expression Profiling Including GPR174 and GNG2 is Associated with Vasovagal Syncope.

    Pediatric Cardiology 36(3):475 (2015) PMID 25367286

    Vasovagal syncope (VVS) causes accidental harm for susceptible patients. However, pathophysiology of this disorder remains largely unknown. In an effort to understanding of molecular mechanism for VVS, genome-wide gene expression profiling analyses were performed on VVS patients at syncope state...
  17. Inhibitory effects of 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside on angiotensin II-induced proliferation of vascular smooth muscle cells.

    Chinese Journal of Integrative Medicine 21(3):204 (2015) PMID 25078359

    To investigate the effect of 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside (TSG), an active component extracted from the root of Polygonum multiflorum, on angiotensin II (Ang II)-induced proliferation of cultured rat vascular smooth muscle cells (VSMCs) and to identify the potential mechanism....
  18. [Effect of different organic fertilizers on bioavailability of soil Cd and Zn].

    Ying yong sheng tai xue bao = The journal of ap... 26(3):826 (2015) PMID 26211065

    The active effect of soil Cd and Zn and their interaction was studied in typical paddy field in south China by monitoring the contents of Cd and Zn in soil and rice in rice fields applied with pig manure, chicken manure or rice straw for 4 years continuously. The results showed that applying pig...
  19. Internalization of aquaporin-4 after collagenase-induced intracerebral hemorrhage.

    Anatomical Record. Part A: Advances in Integrat... 298(3):554 (2015) PMID 25257965

    Brain edema formation following intracerebral hemorrhage (ICH) appears to be related with aquaporin-4 (AQP4), which is critically involved in brain volume homeostasis and water balance. Despite its importance, the regulation of AQP4 expression involved in transmembrane water movements still rema...
  20. [Association of ORMDL3 single nucleotide polymorphisms with lysophosphatidylcho-line and apolipoprotein B levels in children with asthma].

    Zhongguo dang dai er ke za zhi = Chinese journa... 17(3):241 (2015) PMID 25815492

    To study the association of ORMDL3 single nucleotide polymorphisms (SNP) with lysophosphatidylcholine (LysoPC) and apolipoprotein B (apoB) levels. A total of 300 children diagnosed with bronchial asthma between January 2010 and December 2012 were selected for the asthma group, and 298 children d...