Studies on cerebral protection of digoxin against hypoxic-ischemic brain damage in neonatal rats.
Neuroreport 27(12):906 (2016)
Hypoxic-ischemic brain damage (HIBD) is a major cause of neonatal acute deaths and chronic nervous system damage. Our present study was designed to investigate the possible neuroprotective effect of digoxin-induced pharmacological preconditioning after hypoxia-ischemia and underlying mechanisms....
Coblation tonsillectomy under surgical microscopy: A retrospective study.
Journal of International Medical Research 44(4):923 (2016)
A retrospective study to compare surgical parameters and postoperative pain in patients undergoing coblation tonsillectomy with or without microscopic guidance.
Data regarding duration of surgery and hospital stay, intraoperative blood loss, incidence of haemorrhage and postoperative pain scores...
Multi-environment QTL analysis of grain morphology traits and fine mapping of a kernel-width QTL in Zheng58 × SK maize population.
Theoretical and Applied Genetics 129(8):1465 (2016)
Sixteen major QTLs regulating maize kernel traits were mapped in multiple environments and one of them, qKW - 9.2 , was restricted to 630 Kb, harboring 28 putative gene models. To elucidate the genetic basis of kernel traits, a quantitative trait locus (QTL) analysis was conducted in a maize rec...
Monosilicic acid potential in phytoremediation of the contaminated areas.
Chemosphere 157:132 (2016)
The contamination of agricultural areas by heavy metals has a negative influence on food quality and human health. Various remediation techniques have been developed for the removal and/or immobilization of heavy metals (HM) in contaminated soils. Phytoremediation is innovative technology, which...
GRIM-19 inhibition induced autophagy through activation of ERK and HIF-1α not STAT3 in Hela cells.
Tumor Biology 37(7):9789 (2016)
Gene associated with retinoid-interferon-induced mortality (GRIM-19), an important subunit of mitochondrial complex I, has been identified as a tumor suppressor, and its reduced expression has been reported to be associated with tumorigenesis and metastasis. Autophagy has been proposed as a prot...
Fine mapping and candidate gene analysis of the dominant glandless gene Gl 2 (e) in cotton (Gossypium spp.).
Theoretical and Applied Genetics 129(7):1347 (2016)
Dominant glandless gene Gl 2 (e) was fine-mapped to a 15 kb region containing one candidate gene encoding an MYC transcription factor, sequence and expression level of the gene were analyzed. Cottonseed product is an excellent source of oil and protein. However, this nutrition source is greatly ...
Origins and features of oil slicks in the Bohai Sea detected from satellite SAR images.
Marine Pollution Bulletin 106(1-2):149 (2016)
Oil slicks were detected using satellite Synthetic Aperture Radar (SAR) images in 2011. We investigated potential origins and regional and seasonal features of oil slick in the Bohai Sea. Distance between oil slicks and potential origins (ships, seaports, and oil exploitation platforms) and the ...
Combined analysis of pri-miR-34b/c rs4938723 and TP53 Arg72Pro with cervical cancer risk.
Tumor Biology 37(5):6267 (2016)
miR-34 family members can form a p53-miR-34 positive feedback loop and induce apoptosis, DNA repair, angiogenesis, and cell cycle arrest. We conducted a case-control study to examine whether two polymorphisms (i.e., rs4938723 in the promoter of pri-miR-34b/c and TP53 Arg72Pro) were linked to the...
Selective isolation of components from natural volatile oil by countercurrent chromatography with cyclodextrins as selective reagent.
Journal of chromatography. A 1444:99 (2016)
Selective separation of chemical components from seven kinds of volatile oil by countercurrent chromatography with three types of cyclodextrins as selective reagent was investigated in this work. Preparative separation of chemical components from volatile oil is generally quite challenging due t...
KRAS polymorphisms are associated with survival of CRC in Chinese population.
Tumor Biology 37(4):4727 (2016)
rs12245, rs12587, rs9266, rs1137282, rs61764370, and rs712 of KRAS oncogene are characterized in the 3'UTR. The study highlights the important role of these polymorphisms playing in the susceptibility, oxaliplatin-based chemotherapy sensitivity, progression, and prognosis of CRC. Improved multip...
Both endoplasmic reticulum and mitochondrial pathways are involved in oligodendrocyte apoptosis induced by capsular hemorrhage.
Molecular and Cellular Neuroscience 72:64 (2016)
The white matter injury caused by intracerebral hemorrhage (ICH) includes demyelination and axonal injury. Oligodendrocyte apoptosis is reported to be involved in triggering demyelination. Experimental observations indicate that both endoplasmic reticulum and mitochondrial pathways could mediate...
The function of small RNAs in plant biotic stress response.
Journal of Integrative Plant Biology 58(4):312 (2016)
Small RNAs (sRNAs) play essential roles in plants upon biotic stress. Plants utilize RNA silencing machinery to facilitate pathogen-associated molecular pattern-triggered immunity and effector-triggered immunity to defend against pathogen attack or to facilitate defense against insect herbivores...
Microglial polarization dynamics in dorsal spinal cord in the early stages following chronic sciatic nerve damage.
Neuroscience Letters 617:6 (2016)
Peripheral nerve injury can lead to activation of spinal microglia, which can mediate neuroinflammation and contribute to neuropathic pain following nerve injury. Activated microglia may manifest with either pro-inflammatory M1 phenotype or anti-inflammatory M2 phenotype, which may lead to detri...
Pharmacokinetics and Pharmacodynamics of Henagliflozin, a Sodium Glucose Co-Transporter 2 Inhibitor, in Chinese Patients with Type 2 Diabetes Mellitus.
Clinical Drug Investigation 36(3):195 (2016)
Henagliflozin, a selective inhibitor of the renal sodium glucose cotransporter-2, was developed for type 2 diabetes mellitus (T2DM). This study characterized single- and multiple-dose pharmacokinetics and pharmacodynamics of henagliflozin in Chinese patients with T2DM.
Thirty T2DM patients were ...
Cytogenetic Behavior of Trigeneric Hybrid Progeny Involving Wheat, Rye and Psathyrostachys huashanica.
Cytogenetic and Genome Research 148(1):74 (2016)
Trigeneric hybrids are commonly used as bridges to transfer genes from some wild species to cultivated wheat and to measure the genomic interaction between donor species. We previously reported that trigeneric germplasms were produced by crossing wheat-Psathyrostachys huashanica amphiploids (PHW...
Radiotherapy combined with chemotherapy versus radiotherapy alone for early stage nasal natural killer/T-cell lymphoma: a meta-analysis.
Journal of Chemotherapy 28(1):65 (2016)
To compare the efficacy of radiotherapy (RT) plus chemotherapy (CMT) versus RT alone for early stage nasal natural killer (NK)/T-cell lymphoma.
All the eligible studies were searched by PubMed, Medline, Embase and the Cochrane Library. The meta-analysis was performed to compare odds ratios (ORs)...
Clinical efficacy of tiotropium in children with asthma.
Pakistan journal of medical sciences quarterly 32(2):462 (2016)
To investigate the clinical efficacy of tiotropium in children with asthma.
Eighty children with newly diagnosed moderate persistent asthma were enrolled into this study. The children were randomly assigned to the fluticasone propionate aerosol group or the fluticasone propionate aerosol plus ti...
Effect of a controlled-release drug delivery system made of oleanolic acid formulated into multivesicular liposomes on hepatocellular carcinoma in vitro and in vivo.
International Journal of Nanomedicine 11:3111 (2016)
The aim of the present study was to develop a novel dosage form of multivesicular liposomes for oleanolic acid (OA) to overcome its poor solubility, prolong therapeutic drug levels in the blood, and enhance the antitumor effect on hepatocellular carcinoma. OA-encapsulated multivesicular liposome...
Divergent Development of Hexaploid Triticale by a Wheat - Rye -Psathyrostachys huashanica Trigeneric Hybrid Method.
PLoS ONE 11(5):e0155667 (2016)
Hexaploid triticale is an important forage crop and a promising energy plant. Some forms were previously reported for developing the hexaploid triticale, such as crossing tetraploid wheat or hexaploid wheat with rye, crossing hexaploid triticale and/or hexaploid wheat with octoploid triticale, a...
Symptom Clusters in Ovarian Cancer Patients With Chemotherapy After Surgery: A Longitudinal Survey.
CANCER NURSING&trade 39(2):106 (2016)
Ovarian cancer is 1 of the most common malignancies in the female reproductive system. Identification of symptom clusters in ovarian cancer patients may improve management of symptoms.
The objective of this article is to explore the changes in symptom clusters in ovarian cancer patients with adj...