Advanced search×
×
  1. Integration of metabolic databases for the reconstruction of genome-scale metabolic networks.

    BMC Systems Biology 4:114 (2010) PMID 20712863 PMCID PMC2930596

    We report a semi-automated methodology aimed at streamlining the process of metabolic network reconstruction by enabling the integration of different genome-wide databases of metabolic reactions. We present results obtained by applying this methodology to the metabolic network of the plant Arabidops...
  2. Improving limited-projection-angle fluorescence molecular tomography using a co-registered x-ray computed tomography scan.

    Journal of Biomedical Optics 17(12):126011 (2012) PMID 23208296

    We examine the improvement in imaging performance, such as axial resolution and signal localization, when employing limited-projection-angle fluorescence molecular tomography (FMT) together with x-ray computed tomography (XCT) measurements versus stand-alone FMT. For this purpose, we employed living...
  3. FMT-PCCT: Hybrid Fluorescence Molecular Tomography-X-Ray Phase-Contrast CT Imaging of Mouse Models.

    Medical Imaging, IEEE Transactions on 33(7):1434 (2014) PMID 24686244

    We combined herein FMT with emerging X-ray phase-contrast CT (PCCT). PCCT relies on phase shift differences in tissue to achieve soft tissue contrast superior to conventional CT. We demonstrate for the first time FMT-PCCT imaging of different animal models, where FMT and PCCT scans were performed in...
  4. Limited-projection-angle hybrid fluorescence molecular tomography of multiple molecules.

    Journal of Biomedical Optics 19(4):046016 (2014) PMID 24770661

    We investigated multimoiety imaging in the context of a limited-projection-angle hybrid fluorescence molecular tomography (FMT), and x-ray computed tomography implementation and the further registration with positron emission tomography (PET) data. Multichannel FMT systems may image fluorescent prob...
  5. Cardioprotective C-kit⁺ bone marrow cells attenuate apoptosis after acute myocardial infarction in mice - in-vivo assessment with fluorescen...

    Theranostics 3(11):903 (2013) PMID 24312159 PMCID PMC3841340

    We therefore thought to examine the early course of apoptosis following myocardial infarction - in-vivo - and non-invasively determine the effect of c-kit⁺ bone marrow cells on post-MI remodeling. We studied apoptosis in wild-type Kit(+/+) , c-kit mutant Kit(W)/Kit(W-v) and Kit(W)/Kit(W-v) mice afte...