1. Histological characteristics of the myometrium in the postpartum hemorrhage of unknown etiology: a possible involvement of local immune reactions.

    Journal of Reproductive Immunology 110:74 (2015) PMID 26048052

    The aim of this study was to evaluate the histological characteristics of the myometrium obtained in postpartum hemorrhage (PPH) of unknown etiology secondary to uterine atony. These characteristics were selected from among registered cases of clinically suspected amniotic fluid embolism (AFE) a...
  2. Systematic pathological survey of all placentas delivered in a perinatal center

    Placenta 35(10):A11 (2014)

  3. Systematic pathological survey of all placentas delivered in a perinatal center

    Placenta 35(10):A11 (2014)

  4. C1 esterase inhibitor activity in amniotic fluid embolism.

    Critical Care Medicine 42(6):1392 (2014) PMID 24561565

    Amniotic fluid embolism exhibits activation of the complement system and the kallikrein-kinin and coagulofibrinolytic systems. C1 esterase inhibitor is a major inhibitor of C1 esterase and can inhibit plasma kallikrein and also factors XIIa and XIa. Its activity has been shown to be significantl...
  5. C1 esterase inhibitor activity in amniotic fluid embolism.

    Critical Care Medicine 42(6):1392 (2014) PMID 24561565

    Amniotic fluid embolism exhibits activation of the complement system and the kallikrein-kinin and coagulofibrinolytic systems. C1 esterase inhibitor is a major inhibitor of C1 esterase and can inhibit plasma kallikrein and also factors XIIa and XIa. Its activity has been shown to be significantl...
  6. Comparison between placental gene expression of 11β-hydroxysteroid dehydrogenases and infantile growth at 10 months of age.

    Journal of obstetrics and gynaecology (Tokyo, J... 40(2):465 (2014) PMID 24147632

    The local expression of two isoenzymes of 11β-hydroxysteroid dehydrogenase, type 1 (11βHSD-1) and type 2 (11βHSD-2), regulates the access of glucocorticoid hormones to their target cells. Reports on the association between the placental expression of 11βHSD and infantile growth are limited. The ...
  7. Comparison between placental gene expression of 11β-hydroxysteroid dehydrogenases and infantile growth at 10 months of age.

    Journal of obstetrics and gynaecology (Tokyo, J... 40(2):465 (2014) PMID 24147632

    The local expression of two isoenzymes of 11β-hydroxysteroid dehydrogenase, type 1 (11βHSD-1) and type 2 (11βHSD-2), regulates the access of glucocorticoid hormones to their target cells. Reports on the association between the placental expression of 11βHSD and infantile growth are limited. The ...
  8. Attenuation of fibroblast growth factor signaling by poly-N-acetyllactosamine type glycans

    FEBS Letters 587(19):3195 (2013)

    • We found that human sperm treated with endo-β-galactosidase enhanced motility. • Sperm-associated poly-N-acetyllactosamine type glycans are heavily fucosylated. ...
  9. Attenuation of fibroblast growth factor signaling by poly-N-acetyllactosamine type glycans

    FEBS Letters 587(19):3195 (2013) PMID 23968720 PMCID PMC4029356

    • We found that human sperm treated with endo-β-galactosidase enhanced motility. • Sperm-associated poly-N-acetyllactosamine type glycans are heavily fucosylated. ...
  10. Attenuation of fibroblast growth factor signaling by poly-N-acetyllactosamine type glycans.

    FEBS Letters 587(19):3195 (2013) PMID 23968720 PMCID PMC4029356

    Fibroblast growth factors (FGFs) and their receptors are expressed in a variety of mammalian tissues, playing a role in development and cell proliferation. While analyzing human sperm motility, we found that sperm treated with endo-β-galactosidase (EBG), which specifically hydrolyzes poly-N-acet...
  11. Changes of maternal dietary intake, bodyweight and fetal growth throughout pregnancy in pregnant Japanese women.

    Journal of obstetrics and gynaecology (Tokyo, J... 39(9):1383 (2013) PMID 23815608

    The associations among changes in dietary intake, maternal bodyweight, and fetal growth during the course of pregnancy were investigated in a prospective cohort study carried out on 135 Japanese women. Dietary intake was analyzed using digital photos of meals taken over 3 consecutive days, in th...
  12. Changes of maternal dietary intake, bodyweight and fetal growth throughout pregnancy in pregnant Japanese women.

    Journal of obstetrics and gynaecology (Tokyo, J... 39(9):1383 (2013) PMID 23815608

    The associations among changes in dietary intake, maternal bodyweight, and fetal growth during the course of pregnancy were investigated in a prospective cohort study carried out on 135 Japanese women. Dietary intake was analyzed using digital photos of meals taken over 3 consecutive days, in th...
  13. Association between body weight at weaning and remodeling in the subcutaneous adipose tissue of obese adult mice with undernourishment in utero.

    Reproductive Sciences 20(7):813 (2013) PMID 23296035 PMCID PMC3713544

    Rapid growth in infancy considerably increases the risk of obesity and metabolic disorders in adulthood especially among neonates born small. To investigate the mechanism involved, we developed an animal model of undernourishment in utero by maternal caloric restriction, in which the Z scores of...
  14. Association between body weight at weaning and remodeling in the subcutaneous adipose tissue of obese adult mice with undernourishment in utero.

    Reproductive Sciences 20(7):813 (2013) PMID 23296035 PMCID PMC3713544

    Rapid growth in infancy considerably increases the risk of obesity and metabolic disorders in adulthood especially among neonates born small. To investigate the mechanism involved, we developed an animal model of undernourishment in utero by maternal caloric restriction, in which the Z scores of...
  15. Cerebral oxygen saturation evaluated by near-infrared time-resolved spectroscopy (TRS) in pregnant women during caesarean section - a promising new method of maternal monitoring.

    Clinical Physiology and Functional Imaging 33(2):109 (2013) PMID 23383688

    Time-resolved spectroscopy (TRS-20) measures tissue oxygen saturation (%) by evaluating the absolute concentrations of oxygenated, deoxygenated and total haemoglobin based on measurement of the transit time of individual photons through a tissue of interest. We measured tissue oxygen saturation ...
  16. Cerebral oxygen saturation evaluated by near-infrared time-resolved spectroscopy (TRS) in pregnant women during caesarean section - a promising new method of maternal monitoring.

    Clinical Physiology and Functional Imaging 33(2):109 (2013) PMID 23383688

    Time-resolved spectroscopy (TRS-20) measures tissue oxygen saturation (%) by evaluating the absolute concentrations of oxygenated, deoxygenated and total haemoglobin based on measurement of the transit time of individual photons through a tissue of interest. We measured tissue oxygen saturation ...
  17. In vivo regulation of steroid hormones by the Chst10 sulfotransferase in mouse.

    Journal of Biological Chemistry 288(7):5007 (2013) PMID 23269668 PMCID PMC3576103

    Chst10 adds sulfate to glucuronic acid to form a carbohydrate antigen, HNK-1, in glycoproteins and glycolipids. To determine the role of Chst10 in vivo, we generated systemic Chst10-deficient mutant mice. Although Chst10(-/-) mice were born and grew to adulthood with no gross defects, they were ...
  18. In vivo regulation of steroid hormones by the Chst10 sulfotransferase in mouse.

    Journal of Biological Chemistry 288(7):5007 (2013) PMID 23269668 PMCID PMC3576103

    Chst10 adds sulfate to glucuronic acid to form a carbohydrate antigen, HNK-1, in glycoproteins and glycolipids. To determine the role of Chst10 in vivo, we generated systemic Chst10-deficient mutant mice. Although Chst10(-/-) mice were born and grew to adulthood with no gross defects, they were ...
  19. Tumor targeting by a carbohydrate ligand-mimicking peptide.

    Methods in Molecular Biology 1022:369 (2013) PMID 23765676

    Annexin A1 (Anxa1) is a highly specific surface marker of tumor vasculature. We used peptide-displaying phage technology to identify a carbohydrate ligand-mimicking 7-mer peptide, IFLLWQR (IF7), which can target Anxa1 in tumor vasculature. Here, we describe the binding activity of carbohydrate t...
  20. Tumor targeting by a carbohydrate ligand-mimicking peptide.

    Methods in Molecular Biology 1022:369 (2013) PMID 23765676

    Annexin A1 (Anxa1) is a highly specific surface marker of tumor vasculature. We used peptide-displaying phage technology to identify a carbohydrate ligand-mimicking 7-mer peptide, IFLLWQR (IF7), which can target Anxa1 in tumor vasculature. Here, we describe the binding activity of carbohydrate t...