1. 'Mini-GEMs': short, focused e-learning videos in geriatric medicine.

    Clinical Medicine 15 Suppl 3:s27 (2015) PMID 26026021

  2. Physical therapy as an adjunct treatment for people living with HIV/AIDS: an allied health perspective.

    Journal of allied health 43(2):e11 (2014) PMID 24925040

    With the increased life expectancy for people living with HIV/AIDS (PLWHA) has come chronic HIV-related impairments, many of which can be successfully treated by physical therapy (PT). The purpose of this study is to determine common HIV-related impairments that merit PT, HIV providers' PT refer...
  3. Physical therapy as an adjunct treatment for people living with HIV/AIDS: an allied health perspective.

    Journal of allied health 43(2):e11 (2014) PMID 24925040

    With the increased life expectancy for people living with HIV/AIDS (PLWHA) has come chronic HIV-related impairments, many of which can be successfully treated by physical therapy (PT). The purpose of this study is to determine common HIV-related impairments that merit PT, HIV providers' PT refer...
  4. Physical therapy as an adjunct treatment for people living with HIV/AIDS: an allied health perspective.

    Journal of allied health 43(2):e11 (2014) PMID 24925040

    With the increased life expectancy for people living with HIV/AIDS (PLWHA) has come chronic HIV-related impairments, many of which can be successfully treated by physical therapy (PT). The purpose of this study is to determine common HIV-related impairments that merit PT, HIV providers' PT refer...
  5. Geriatric medicine workforce planning: a giant geriatric problem or has the tide turned?

    Clinical Medicine 14(2):102 (2014) PMID 24715117

    The UK's population is ageing and an adequately staffed geriatric medicine workforce is essential for high quality care. We evaluated the current and future geriatric medicine workforce, drawing on data relating to the UK population, current geriatric medicine consultants and trainees, recruitme...
  6. Geriatric medicine workforce planning: a giant geriatric problem or has the tide turned?

    Clinical Medicine 14(2):102 (2014) PMID 24715117

    The UK's population is ageing and an adequately staffed geriatric medicine workforce is essential for high quality care. We evaluated the current and future geriatric medicine workforce, drawing on data relating to the UK population, current geriatric medicine consultants and trainees, recruitme...
  7. USP-11 as a predictive and prognostic factor following neoadjuvant therapy in women with breast cancer.

    The Cancer Journal 19(1):10 (2013) PMID 23337751 PMCID PMC3568679

    USP-11, a member of the ubiquitin-specific protease family, has emerged as an essential regulator of double-strand break repair. Few studies have shown that silencing USP-11 led to hypersensitivity to poly(ADP-ribose) polymerase inhibition, ionizing radiation, and DNA-damaging agents. We sought ...
  8. Announcing the surgical standards manual project: a call for volunteers.

    Bulletin of the American College of Surgeons 97(9):67 (2012) PMID 23002684

  9. Announcing the surgical standards manual project: a call for volunteers.

    Bulletin of the American College of Surgeons 97(9):67 (2012) PMID 23002684

  10. Whole-genome analysis informs breast cancer response to aromatase inhibition.

    Nature 486(7403):353 (2012) PMID 22722193 PMCID PMC3383766

    To correlate the variable clinical features of oestrogen-receptor-positive breast cancer with somatic alterations, we studied pretreatment tumour biopsies accrued from patients in two studies of neoadjuvant aromatase inhibitor therapy by massively parallel sequencing and analysis. Eighteen signi...
  11. Whole-genome analysis informs breast cancer response to aromatase inhibition.

    Nature 486(7403):353 (2012) PMID 22722193 PMCID PMC3383766

    To correlate the variable clinical features of oestrogen-receptor-positive breast cancer with somatic alterations, we studied pretreatment tumour biopsies accrued from patients in two studies of neoadjuvant aromatase inhibitor therapy by massively parallel sequencing and analysis. Eighteen signi...
  12. Whole-genome analysis informs breast cancer response to aromatase inhibition.

    Nature 486(7403):353 (2012) PMID 22722193 PMCID PMC3383766

    To correlate the variable clinical features of oestrogen-receptor-positive breast cancer with somatic alterations, we studied pretreatment tumour biopsies accrued from patients in two studies of neoadjuvant aromatase inhibitor therapy by massively parallel sequencing and analysis. Eighteen signi...
  13. Spatial and visuospatial working memory tests predict performance in classic multiple-object tracking in young adults, but nonspatial measures of the executive do not.

    Attention, Perception & Psychophysics 74(2):300 (2012) PMID 22076680

    An individual-differences approach was used to investigate the roles of visuospatial working memory and the executive in multiple-object tracking. The Corsi Blocks and Visual Patterns Tests were used to assess visuospatial working memory. Two relatively nonspatial measures of the executive were ...
  14. Spatial and visuospatial working memory tests predict performance in classic multiple-object tracking in young adults, but nonspatial measures of the executive do not.

    Attention, Perception & Psychophysics 74(2):300 (2012) PMID 22076680

    An individual-differences approach was used to investigate the roles of visuospatial working memory and the executive in multiple-object tracking. The Corsi Blocks and Visual Patterns Tests were used to assess visuospatial working memory. Two relatively nonspatial measures of the executive were ...
  15. Fitting parametric random effects models in very large data sets with application to VHA national data.

    BMC Medical Research Methodology 12:163 (2012) PMID 23095325 PMCID PMC3542162

    With the current focus on personalized medicine, patient/subject level inference is often of key interest in translational research. As a result, random effects models (REM) are becoming popular for patient level inference. However, for very large data sets that are characterized by large sample...
  16. Fitting parametric random effects models in very large data sets with application to VHA national data.

    BMC Medical Research Methodology 12:163 (2012) PMID 23095325 PMCID PMC3542162

    With the current focus on personalized medicine, patient/subject level inference is often of key interest in translational research. As a result, random effects models (REM) are becoming popular for patient level inference. However, for very large data sets that are characterized by large sample...
  17. Tamoxifen downregulates ets oncogene family members ETV4 and ETV5 in benign breast tissue: implications for durable risk reduction.

    Cancer Prevention Research 4(11):1852 (2011) PMID 21778330 PMCID PMC3208724

    Five years of tamoxifen reduces breast cancer risk by nearly 50% but is associated with significant side effects and toxicities. A better understanding of the direct and indirect effects of tamoxifen in benign breast tissue could elucidate new mechanisms of breast carcinogenesis, suggest novel c...
  18. Tamoxifen downregulates ets oncogene family members ETV4 and ETV5 in benign breast tissue: implications for durable risk reduction.

    Cancer Prevention Research 4(11):1852 (2011) PMID 21778330 PMCID PMC3208724

    Five years of tamoxifen reduces breast cancer risk by nearly 50% but is associated with significant side effects and toxicities. A better understanding of the direct and indirect effects of tamoxifen in benign breast tissue could elucidate new mechanisms of breast carcinogenesis, suggest novel c...
  19. Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based intrinsic subtype--ACOSOG Z1031.

    Journal of Clinical Oncology 29(17):2342 (2011) PMID 21555689 PMCID PMC3107749

    Preoperative aromatase inhibitor (AI) treatment promotes breast-conserving surgery (BCS) for estrogen receptor (ER)-positive breast cancer. To study this treatment option, responses to three AIs were compared in a randomized phase II neoadjuvant trial designed to select agents for phase III inve...
  20. Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based intrinsic subtype--ACOSOG Z1031.

    Journal of Clinical Oncology 29(17):2342 (2011) PMID 21555689 PMCID PMC3107749

    Preoperative aromatase inhibitor (AI) treatment promotes breast-conserving surgery (BCS) for estrogen receptor (ER)-positive breast cancer. To study this treatment option, responses to three AIs were compared in a randomized phase II neoadjuvant trial designed to select agents for phase III inve...