Interaction of a biosurfactant, Surfactin with a cationic Gemini surfactant in aqueous solution.
Journal of Colloid and Interface Science 481:201 (2016)
The interaction between biosurfactant Surfactin and cationic Gemini surfactant ethanediyl-1,3-bis(dodecyldimethylammonium bromide) (abbreviated as 12-3-12) was investigated using turbidity, surface tension, dynamic light scattering (DLS) and small angle neutron scattering (SANS). Analysis of cri...
Growing tumors induce a local STING dependent Type I IFN response in dendritic cells.
International Journal of Cancer 139(6):1350 (2016)
The importance of endogenous Type I IFNs in cancer immune surveillance is well established by now. Their role in polarization of tumor-associated neutrophilic granulocytes into anti-tumor effector cells has been recently demonstrated. Yet, the cellular source of Type I IFNs as well as the mode o...
High-efficiency transduction and specific expression of ChR2opt for optogenetic manipulation of primary cortical neurons mediated by recombinant adeno-associated viruses.
Journal of Biotechnology 233:171 (2016)
In recent years, optogenetic approaches have significantly advanced the experimental repertoire of cellular and functional neuroscience. Yet, precise and reliable methods for specific expression of optogenetic tools remain challenging. In this work, we studied the transduction efficiency of seve...
Investigation on the differences of accumulating Escherichia coli in three types of shellfish species, involving in the environmental factors.
Marine Pollution Bulletin 109(1):81 (2016)
This study investigated accumulation of Escherichia coli and aerobic colony count in three types of shellfish species. The results indicated that the capability of accumulating E. coli and aerobic colony count for Sinonovacula constricta was stronger than that for Meretrix meretrix and Tegillarc...
Periodontal Wound Healing by Transplantation of Jaw Bone Marrow-Derived Mesenchymal Stem Cells in Chitosan/Anorganic Bovine Bone Carrier Into One-Wall Infrabony Defects in Beagles.
Journal of Periodontology 87(8):971 (2016)
This study aims to evaluate the performance of chitosan/anorganic bovine bone (C/ABB) scaffold seeded with human jaw bone marrow-derived mesenchymal stem cells (hJBMMSCs) in supporting the healing/repair of 1-wall critical-size periodontal defects.
Physical properties of the C/ABB scaffold were ...
Consumption of whole grains in relation to mortality from all causes, cardiovascular disease, and diabetes: Dose-response meta-analysis of prospective cohort studies.
Medicine (Baltimore) 95(33):e4229 (2016)
To investigate the correlation between consumption of whole grains and the risk of all-cause, cardiovascular disease (CVD), and diabetes-specific mortality according to a dose-response meta-analysis of prospective cohort studies.
Observational cohort studies, which reported associations between ...
Maternal Hemoglobin Concentration during Gestation and Risk of Anemia in Infancy: Secondary Analysis of a Randomized Controlled Trial.
The Journal of Pediatrics 175:106 (2016)
This study examined the relationship between maternal hemoglobin (Hb) concentration and the risk of anemia in infancy.
This analysis included 17 193 women who entered the trial when they were ≥20 years of age, no more than 20 weeks of gestation, had mild or no anemia, and delivered singleton liv...
Levels of folate receptor autoantibodies in maternal and cord blood and risk of neural tube defects in a Chinese population.
Birth Defects Research Part A: Clinical and Mol... 106(8):685 (2016)
After years of periconceptional folic acid supplementation, the prevalence of neural tube defects (NTDs) remains stable following the remarkable reduction observed immediately after the fortification practice. There is accumulating evidence that folate receptor (FR) autoimmunity may play a role ...
In Situ Detection of Regulatory T Cells in Human Genital Herpes Simplex Virus Type 2 (HSV-2) Reactivation and Their Influence on Spontaneous HSV-2 Reactivation.
Journal of Infectious Diseases 214(1):23 (2016)
Herpes simplex virus type 2 (HSV-2) reactivation is accompanied by a sustained influx of CD4(+) and CD8(+) T cells that persist in genital tissue for extended periods. While CD4(+) T cells have long been recognized as being present in herpetic ulcerations, their role in subclinical reactivation ...
MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis.
International Journal of Molecular Medicine 38(1):201 (2016)
Osteoarthritis (OA) is the most prevalent degenerative joint disease with multifactorial etiology caused by risk factors such as ageing, obesity and trauma. Previously, it was reported that the inhibition of microRNA-34a (miR-34a) may reduce rat chondrocyte apoptosis induced by IL-1β, whereas th...
Exposure of methyl mercury in utero and the risk of neural tube defects in a Chinese population.
Reproductive Toxicology 61:131 (2016)
To determine if exposure to methyl mercury (MeHg) in utero is associated with an elevated risk of neural tube defects (NTDs), we measured its concentration in the placentas of 36 anencephalic and 44 spina bifida cases, as well as in 50 healthy controls. The median MeHg concentration in NTD cases...
Understanding Nanostructuring Processes in Thermoelectrics and Their Effects on Lattice Thermal Conductivity.
Advanced Materials (FRG) 28(14):2737 (2016)
Cooling rates of molten PbTe-CdTe compositions play a determinant role in defining the nanoscale precipitate size distribution and the corresponding number densities, resulting in distinct trends of lattice thermal conductivity evolution with varying CdTe fractions.
© 2016 WILEY-VCH Verlag GmbH...
Ligand-Free Noble Metal Nanocluster Catalysts on Carbon Supports via "Soft" Nitriding.
Journal of the American Chemical Society 138(14):4718 (2016)
We report a robust, universal "soft" nitriding method to grow in situ ligand-free ultrasmall noble metal nanocatalysts (UNMN; e.g., Au, Pd, and Pt) onto carbon. Using low-temperature urea pretreatment at 300 °C, soft nitriding enriches nitrogen-containing species on the surface of carbon support...
Prevalence and trend of neural tube defects in five counties in Shanxi province of Northern China, 2000 to 2014.
Birth Defects Research Part A: Clinical and Mol... 106(4):267 (2016)
The prevalence of neural tube defects (NTDs) in northern China is among the highest in the world. A massive folic acid supplementation program as a specific countermeasure was introduced in 2009. Examining trends in NTD prevalence may provide evidence for future intervention.
Data for 2000 to 20...
Caveolin-1 promotes tumor growth and metastasis via autophagy inhibition in hepatocellular carcinoma.
Clinics and research in hepatology and gastroen... 40(2):169 (2016)
Caveolin-1 is a member of the caveolae family of membrane proteins. Although some researchers have investigated the function of Caveolin-1 in hepatocellular carcinoma, the mechanism of Caveolin-1 action and its prognostic value in hepatocellular carcinoma remain unclear.
Caveolin-1 expression wa...
Hepatitis B surface antigen in oocytes and embryos may not result in vertical transmission to offspring of hepatitis B virus carriers.
Fertility and Sterility 105(4):1010 (2016)
To investigate the vertical transmission of hepatitis B virus (HBV) via embryos to children and whether HBV in embryos has an effect on the development of the fetus and pregnancy outcomes of in vitro fertilization and embryo transfer (IVF-ET).
Long-term follow-up study.
Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates.
ACS Chemical Biology 11(3):763 (2016)
Coactivator-associated arginine methyltransferase 1 (CARM1) is a protein arginine N-methyltransferase (PRMT) enzyme that has been implicated in a variety of cancers. CARM1 is known to methylate histone H3 and nonhistone substrates. To date, several crystal structures of CARM1 have been solved, i...
The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons.
Immunity 44(3):597 (2016)
The cationic polysaccharide chitosan is an attractive candidate adjuvant capable of driving potent cell-mediated immunity, but the mechanism by which it acts is not clear. We show that chitosan promotes dendritic cell maturation by inducing type I interferons (IFNs) and enhances antigen-specific...
A facile synthesis of Fe3C@mesoporous carbon nitride nanospheres with superior electrocatalytic activity.
Nanoscale 8(10):5441 (2016)
We report a colloidal amphiphile-templating approach to preparing nanosized Fe3C encapsulated within mesoporous nitrogen-doped carbon nanospheres (Fe3C@mCN). The obtained Fe3C@mCN hybrids having a high surface area and ultrafine Fe3C nanocrystals exhibited superior activity and durability for ox...
Inhibition of HSP90 by AUY922 Preferentially Kills Mutant KRAS Colon Cancer Cells by Activating Bim through ER Stress.
Molecular Cancer Therapeutics 15(3):448 (2016)
Oncogenic mutations of KRAS pose a great challenge in the treatment of colorectal cancer. Here we report that mutant KRAS colon cancer cells are nevertheless more susceptible to apoptosis induced by the HSP90 inhibitor AUY922 than those carrying wild-type KRAS. Although AUY922 inhibited HSP90 ac...