1. Effect of desmopressin on platelet aggregation and blood loss in patients undergoing valvular heart surgery.

    Chinese Medical Journal 128(5):644 (2015) PMID 25698197

    Blood loss after cardiac surgery can be caused by impaired platelet (PLT) function after cardiopulmonary bypass. Desmopressin or 1-deamino-8-D-arginine vasopressin (DDAVP) is a synthetic analog of vasopressin. DDAVP can increase the level of von Willebrand factor and coagulation factor VIII, thu...
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  2. Markers of macromolecular oxidative damage in maternal serum and risk of neural tube defects in offspring.

    Free Radical Biology and Medicine 80:27 (2015) PMID 25542138

    Neural tube defects (NTDs) are among the most common and severe congenital malformations. To examine the association between markers of macromolecular oxidative damage and risk of NTDs, we measured levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), protein carbonyl (PC), and 8-iso-prostaglandin F2α...
  3. Changes in folic acid supplementation behaviour among women of reproductive age after the implementation of a massive supplementation programme in China.

    Public Health Nutrition 18(4):582 (2015) PMID 24844654

    To examine changes in periconceptional folic acid supplementation behaviour among Chinese women of reproductive age after the implementation of a folic acid supplementation programme. Two cross-sectional surveys were conducted. One survey was before (2002-2004) and the other was after (2011-2012...
  4. Involvement of vacuolar H(+) -ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720.

    Pigment Cell & Melanoma Research 28(2):171 (2015) PMID 25358761

    Targeting the sphingosine 1-phosphate (S1P)/S1P receptor (S1PR) signalling axis is emerging as a promising strategy in the treatment of cancer. However, the effect of such an approach on survival of human melanoma cells remains less understood. Here, we show that the sphingosine analogue FTY720 ...
  5. High Levels of Hepatitis B Surface Antigen are Associated with Poorer Survival and Early Recurrence of Hepatocellular Carcinoma in Patients with Low Hepatitis B Viral Loads.

    Annals of Surgical Oncology 22(3):843 (2015) PMID 25269529

    Recurrence is a disastrous outcome in patients with hepatitis-related hepatocellular carcinoma (HCC) who have undergone curative resection, and little is known about whether high levels of hepatitis B surface antigen (HBsAg) increase the risk of HCC recurrence. This retrospective study included ...
  6. Small-time local controllability of spacecraft attitude using control moment gyros

    Automatica 53:141 (2015)

    Nonlinear controllability theory is utilized to investigate the small-time local controllability (STLC) of the combined dynamics of a spacecraft with control moment gyros (CMGs). Specifically speaking, with three or more independent-type CMGs, the dynamics are STLC from, and hence can ...
  7. CXCR5+ CD4+ T follicular helper cells participate in the pathogenesis of primary biliary cirrhosis.

    Hepatology 61(2):627 (2015) PMID 25042122

    There is increasing interest in the role of T follicular helper (Tfh) cells in autoimmunity from the perspective of both their role in breach of tolerance and their effects on the natural history of disease progression. Indeed, the critical role of Tfh cells in autoimmunity is further highlighte...
  8. Towards complexity analysis of User Authorization Query problem in RBAC

    Computers & Security 48:116 (2015)

    The User Authorization Query (UAQ) problem for RBAC is to determine whether there exists an optimum set of roles to be activated to provide a particular set of permissions requested by a user. It is a key issue related to efficiently handling users' access requests. Previous definition...
  9. Two new triterpenoid saponins from rhizome of Anemone amurensis.

    Journal of Asian Natural Products Research 17(2):132 (2015) PMID 25486328

    Two new triterpenoid saponins were isolated from the 70% ethanol extract of the rhizome of Anemone amurensis, they are oleanolic acid 28-O-β-d-glucopyranosyl-(1 → 3)-α-l-rhamnopyranosyl-(1 → 4)-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranosyl ester (1) and 23,27-dihydroxy oleanolic acid 3-O-α-l-ara...
  10. PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma.

    Oncotarget 6(2):846 (2015) PMID 25514599

    Pyruvate kinase M2 (PKM2) is a member of the pyruvate kinase family. Recent work has defined the "non-metabolic" functions of PKM2. However, the role of PKM2 in HCC remains unclear. To investigate the role of PKM2 in tumor growth, invasion and the prognosis of hepatocellular carcinoma (HCC), PKM...
  11. Levels of polycyclic aromatic hydrocarbons in maternal serum and risk of neural tube defects in offspring.

    Environmental Science & Technology 49(1):588 (2015) PMID 25488567

    Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants, and have been reported to be a risk factor for human neural tube defects (NTDs). We investigated the relationship between PAH concentrations in maternal serum and NTD risk in offspring using a case-control study des...
  12. Levels of polycyclic aromatic hydrocarbons in maternal serum and risk of neural tube defects in offspring.

    Environmental Science & Technology 49(1):588 (2015) PMID 25488567 PMCID PMC4291766

    Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants, and have been reported to be a risk factor for human neural tube defects (NTDs). We investigated the relationship between PAH concentrations in maternal serum and NTD risk in offspring using a case-control study des...
  13. Levels of polycyclic aromatic hydrocarbons in maternal serum and risk of neural tube defects in offspring.

    Environmental Science & Technology 49(1):588 (2015) PMID 25488567 PMCID PMC4291766

    Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants, and have been reported to be a risk factor for human neural tube defects (NTDs). We investigated the relationship between PAH concentrations in maternal serum and NTD risk in offspring using a case-control study des...
  14. Levels of PAH-DNA adducts in cord blood and cord tissue and the risk of fetal neural tube defects in a Chinese population.

    NeuroToxicology 46:73 (2015) PMID 25522656

    Maternal exposure to polycyclic aromatic hydrocarbons (PAHs) has been shown to be associated with an elevated risk for neural tube defects (NTDs). In the human body, PAHs are bioactivated and the resultant reactive epoxides can covalently bind to DNA to form PAH-DNA adducts, which may, in turn, ...
  15. Dietary folate intake levels in rural women immediately before pregnancy in Northern China.

    Birth Defects Research Part A: Clinical and Mol... 103(1):27 (2015) PMID 25066482

    The study aims to assess dietary folate levels and food sources in women immediately before pregnancy in a rural area of northern China associated with a high prevalence of neural tube defects. Information was collected by face-to-face interviews with women who sought premarital healthcare and p...
  16. Effect of desmopressin on platelet aggregation and blood loss in patients undergoing valvular heart surgery.

    Chinese Medical Journal 128(5):644 (2015) PMID 25698197

    Blood loss after cardiac surgery can be caused by impaired platelet (PLT) function after cardiopulmonary bypass. Desmopressin or 1-deamino-8-D-arginine vasopressin (DDAVP) is a synthetic analog of vasopressin. DDAVP can increase the level of von Willebrand factor and coagulation factor VIII, thu...
    PDF not found
  17. Impaired Function of CD4+ T Follicular Helper (Tfh) Cells Associated with Hepatocellular Carcinoma Progression.

    PLoS ONE 10(2):e0117458 (2015) PMID 25689070

    CD4+ T follicular helper (Tfh) cells, a new subset of immune cells, have been demonstrated to be involved in the development and prognosis of tumors. However, their functional role in human hepatocellular carcinoma (HCC) is relatively unknown, and the detailed mechanisms in HCC development remai...
  18. Integrated regulatory mechanisms of miRNAs and targeted genes involved in colorectal cancer.

    International journal of clinical and experimen... 8(1):517 (2015) PMID 25755742

    CRC (Colorectal cancer) is a lethal cancer for death worldwide and the underlying pathological mechanisms for CRC progression remain unclear. We aimed to explore the regulatory mechanism of CRC and provide novel biomarkers for CRC screening. Downloading from GEO (Gene Expression Omnibus) databas...
  19. Levels of PAH-DNA adducts in cord blood and cord tissue and the risk of fetal neural tube defects in a Chinese population.

    NeuroToxicology 46:73 (2015) PMID 25522656

    Maternal exposure to polycyclic aromatic hydrocarbons (PAHs) has been shown to be associated with an elevated risk for neural tube defects (NTDs). In the human body, PAHs are bioactivated and the resultant reactive epoxides can covalently bind to DNA to form PAH-DNA adducts, which may, in turn, ...
  20. Impaired Function of CD4+ T Follicular Helper (Tfh) Cells Associated with Hepatocellular Carcinoma Progression.

    PLoS ONE 10(2):e0117458 (2015) PMID 25689070 PMCID PMC4331507

    CD4+ T follicular helper (Tfh) cells, a new subset of immune cells, have been demonstrated to be involved in the development and prognosis of tumors. However, their functional role in human hepatocellular carcinoma (HCC) is relatively unknown, and the detailed mechanisms in HCC development remai...