1. Stuck Inside a Cloud: Optimizing Sedation to Reduce ICU-Associated Delirium in Geriatric Patients.

    Critical Care Nursing Quarterly 38(3):245 (2015) PMID 26039646

    Elderly population account for more than 50% of all intensive care admissions, and during their stay, up to 87% of them suffer from delirium. There is a large body of evidence demonstrating increased mortality and worse cognitive function for elderly patients who become delirious during their in...
  2. Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model.

    Nature Communications 6:7339 (2015) PMID 26081744

    Diseases of lipid metabolism are a major cause of human morbidity, but no animal model entirely recapitulates human lipoprotein metabolism. Here we develop a xenograft mouse model using hepatocytes from a patient with familial hypercholesterolaemia caused by loss-of-function mutations in the low...
  3. A study in scarlet: restrictive red blood cell transfusion strategy.

    Critical Care Nursing Quarterly 38(2):217 (2015) PMID 25741963

    Anemia due to various etiologies occurs in critically ill patients requiring blood transfusion. Traditional transfusion goals guide our transfusion to achieve a hemoglobin goal of at least 10 g/dL. However, it is becoming increasingly evident that a restrictive transfusion goal of 7 g/dL may imp...
  4. Follow me down the K-hole: ketamine and its modern applications.

    Critical Care Nursing Quarterly 38(2):211 (2015) PMID 25741962

    Ketamine is a versatile anesthetic agent that has been in use since the Vietnam War. Its popularity grew in war time due to its unique pharmacological properties, yet its use dwindled because of some of its adverse effects. However, in specialty areas, ketamine remains the drug of choice and its...
  5. A study in scarlet: restrictive red blood cell transfusion strategy.

    Critical Care Nursing Quarterly 38(2):217 (2015) PMID 25741963

    Anemia due to various etiologies occurs in critically ill patients requiring blood transfusion. Traditional transfusion goals guide our transfusion to achieve a hemoglobin goal of at least 10 g/dL. However, it is becoming increasingly evident that a restrictive transfusion goal of 7 g/dL may imp...
  6. Follow Me Down the K-hole: Ketamine and Its Modern Applications.

    Critical Care Nursing Quarterly 38(2):211 (2015) PMID 25741962

    Ketamine is a versatile anesthetic agent that has been in use since the Vietnam War. Its popularity grew in war time due to its unique pharmacological properties, yet its use dwindled because of some of its adverse effects. However, in specialty areas, ketamine remains the drug of choice and its...
  7. Propofol infusion syndrome: a rare but lethal complication.

    Nursing 44(12):11 (2014) PMID 25406773

  8. Propofol infusion syndrome: a rare but lethal complication.

    Nursing 44(12):11 (2014) PMID 25406773

  9. Propofol infusion syndrome: A rare but lethal complication.

    Nursing 44(12):11 (2014) PMID 25406773

  10. Dexamethasone's effect in the retrocochlear auditory centers of a noise-induced hearing loss mouse model.

    Otolaryngology -- Head and Neck Surgery 151(4):667 (2014) PMID 25113508

    Examine prophylactic effects of dexamethasone (Dex) in retrocochlear auditory centers in a noise-induced hearing loss (NIHL) mouse model. Prospective animal study. Academic research center. Thirty-two mice were divided into control, untreated, saline (2 and 10 µL), and Dex (2 and 10 µL) groups. ...
  11. Dexamethasone's effect in the retrocochlear auditory centers of a noise-induced hearing loss mouse model.

    Otolaryngology -- Head and Neck Surgery 151(4):667 (2014) PMID 25113508

    Examine prophylactic effects of dexamethasone (Dex) in retrocochlear auditory centers in a noise-induced hearing loss (NIHL) mouse model. Prospective animal study. Academic research center. Thirty-two mice were divided into control, untreated, saline (2 and 10 µL), and Dex (2 and 10 µL) groups. ...
  12. Technical note: component separation technique with double-layered biologic mesh placement for neonate with large gastroschisis.

    Journal of Plastic, Reconstructive & Aesthetic ... 67(9):e230 (2014) PMID 24838069

  13. Outcomes of Children After Esophagogastroduodenoscopy for Chronic Abdominal Pain

    Clinical Gastroenterology and Hepatology 12(6):963 (2014)

    Background & Aims Chronic abdominal pain is the most common indication for esophagogastroduodenoscopy (EGD) in children. However, little is known about the accuracy of EGD-based diagnosis or the outcomes of the patients who undergo this procedure. We examined the diagnostic y...
  14. Outcomes of children after esophagogastroduodenoscopy for chronic abdominal pain.

    Clinical Gastroenterology and Hepatology 12(6):963 (2014) PMID 24016631

    Chronic abdominal pain is the most common indication for esophagogastroduodenoscopy (EGD) in children. However, little is known about the accuracy of EGD-based diagnosis or the outcomes of the patients who undergo this procedure. We examined the diagnostic yield of EGD and short-term outcomes of...
  15. Outcomes of children after esophagogastroduodenoscopy for chronic abdominal pain.

    Clinical Gastroenterology and Hepatology 12(6):963 (2014) PMID 24016631

    Chronic abdominal pain is the most common indication for esophagogastroduodenoscopy (EGD) in children. However, little is known about the accuracy of EGD-based diagnosis or the outcomes of the patients who undergo this procedure. We examined the diagnostic yield of EGD and short-term outcomes of...
  16. Outcomes of children after esophagogastroduodenoscopy for chronic abdominal pain.

    Clinical Gastroenterology and Hepatology 12(6):963 (2014) PMID 24016631 PMCID PMC4412350

    Chronic abdominal pain is the most common indication for esophagogastroduodenoscopy (EGD) in children. However, little is known about the accuracy of EGD-based diagnosis or the outcomes of the patients who undergo this procedure. We examined the diagnostic yield of EGD and short-term outcomes of...
  17. Academic rhinology: a survey of residency programs and rhinology faculty in the United States.

    Allergy & Rhinology 4(4):321 (2014) PMID 24407909

    Rhinology has rapidly evolved as a subspecialty over the past decade. The professional activities of rhinology faculty in otolaryngology residency programs is an important defining feature of this process but remains incompletely understood. An examination of faculty profiles of otolaryngology r...
  18. Academic rhinology: a survey of residency programs and rhinology faculty in the United States.

    Allergy & Rhinology 4(4):321 (2014) PMID 24407909

    Rhinology has rapidly evolved as a subspecialty over the past decade. The professional activities of rhinology faculty in otolaryngology residency programs is an important defining feature of this process but remains incompletely understood. An examination of faculty profiles of otolaryngology r...
  19. Vertebrate animal models of glioma: Understanding the mechanisms and developing new therapies

    Biochimica et Biophysica Acta (BBA) - Reviews o... 1836(1):158 (2013) PMID 23618720 PMCID PMC3729034

    Glioblastoma Multiforme (GBM) is recognized as one of the most deadly cancers characterized by cellular atypia, severe necrosis, and high rate of angiogenesis. In this review, we discuss a diversified group of GBM xenograft models and compare them with the genetically engineered mouse ...
  20. ZIP4 is a novel molecular marker for glioma.

    Neuro-Oncology 15(8):1008 (2013) PMID 23595627 PMCID PMC3714151

    Dysregulated zinc transport has been observed in many cancers. However, the status of zinc homeostasis and the expression profile of zinc transporters in brain and brain tumors have not been reported. The gene profiles of 14 zinc importers (ZIPs) and 10 zinc exporters (ZnTs) in patients with gli...