1. Isoform-specific localization of Nogo protein in the optic pathway of mouse embryos.

    Journal of Comparative Neurology 524(11):2322 (2016) PMID 26718118

    Expression of Nogo protein was investigated in the optic pathway of embryonic mice by using isoform-specific antibodies Bianca and 11C7, which recognize Nogo-A/B and Nogo-A, respectively. Our previous reports from using antibody N18 have shown that Nogo is localized on the radial glia in the ret...
  2. HDAC5 controls the functions of Foxp3(+) T-regulatory and CD8(+) T cells.

    International Journal of Cancer 138(10):2477 (2016) PMID 26704363

    Histone/protein deacetylases (HDACs) are frequently upregulated in human malignancies and have therefore become therapeutic targets in cancer therapy. However, inhibiting certain HDAC isoforms can have protolerogenic effects on the immune system, which could make it easier for tumor cells to eva...
  3. Improved renal ischemia tolerance in females influences kidney transplantation outcomes.

    Journal of Clinical Investigation 126(5):1968 (2016) PMID 27088798 PMCID PMC4855926

    Experimentally, females show an improved ability to recover from ischemia-reperfusion injury (IRI) compared with males; however, this sex-dependent response is less established in humans. Here, we developed a series of murine renal ischemia and transplant models to investigate sex-specific effec...
  4. Targeting Sirtuin-1 prolongs murine renal allograft survival and function.

    Kidney International 89(5):1016 (2016) PMID 27083279 PMCID PMC4834143

    Current immunosuppressive medications used after transplantation have significant toxicities. Foxp3(+) T-regulatory cells can prevent allograft rejection without compromising protective host immunity. Interestingly, inhibiting the class III histone/protein deacetylase Sirtuin-1 can augment Foxp3...
  5. Morphology and Phylogeny of Three Pleuronema Species (Ciliophora, Scuticociliatia) from Hangzhou Bay, China, with Description of Two New Species, P. binucleatum n. sp. and P. parawiackowskii n. sp.

    The Journal of protozoology 63(3):287 (2016) PMID 26452585

    The morphology and phylogeny of Pleuronema binucleatum n. sp., P. parawiackowskii n. sp., and P. marinum Dujardin 1841, collected from Hangzhou Bay estuary, China, were investigated using standard methods. Pleuronema binucleatum n. sp. can be identified by possessing about 90-120 × 35-50 μm cell...
  6. Morphology and molecular phylogeny of Pleuronema orientale spec. nov. and Pleuronema paucisaetosum spec. nov. (Ciliophora, Scuticociliata) from Hangzhou Bay, China.

    International Journal of Systematic and Evoluti... 65(12):4800 (2015) PMID 26431884

    Two novel species, Pleuronema orientale spec. nov. and Pleuronema paucisaetosum spec. nov., isolated from coastal waters of Hangzhou Bay, China, were investigated with standard methods. Pleuronema orientale is characterized as follows: size in vivo 95-135 × 50-85 μm; usually one spherical macron...
  7. Thiol-Based Potent and Selective HDAC6 Inhibitors Promote Tubulin Acetylation and T-Regulatory Cell Suppressive Function.

    ACS Medicinal Chemistry Letters 6(11):1156 (2015) PMID 26617971 PMCID PMC4645251

    Several new mercaptoacetamides were synthesized and studied as HDAC6 inhibitors. One compound, 2b, bearing an aminoquinoline cap group, was found to show 1.3 nM potency at HDAC6, with >3000-fold selectivity over HDAC1. 2b also showed excellent efficacy at increasing tubulin acetylation in rat pr...
  8. FOXP3⁺ regulatory T cell development and function require histone/protein deacetylase 3.

    Journal of Clinical Investigation 125(8):3304 (2015) PMID 26237045 PMCID PMC4563765

  9. Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival.

    FASEB Journal 29(6):2315 (2015) PMID 25681462 PMCID PMC4447222

    Conventional T (Tcon) cells and Foxp3(+) T-regulatory (Treg) cells are thought to have differing metabolic requirements, but little is known of mitochondrial functions within these cell populations in vivo. In murine studies, we found that activation of both Tcon and Treg cells led to myocyte en...
  10. FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.

    Journal of Clinical Investigation 125(3):1111 (2015) PMID 25642770 PMCID PMC4362235

    Treg dysfunction is associated with a variety of inflammatory diseases. Treg populations are defined by expression of the oligomeric transcription factor FOXP3 and inability to produce IL-2, a cytokine required for T cell maintenance and survival. FOXP3 activity is regulated post-translationally...
  11. Facile sand enhanced electro-flocculation for cost-efficient harvesting of Dunaliella salina.

    Bioresource Technology 187:326 (2015) PMID 25863210

    Energy consumption and water resource in the cultivation and harvesting steps still need to be minimized for the popularization of the microalgae-based products. An efficient electro-flocculation method for harvesting Dunaliella Salina integrated with local sand has been successfully applied. Sa...
  12. Extrafine HFA-beclomethasone dipropionate versus budesonide for asthma: a meta-analysis.

    International journal of clinical and experimen... 8(1):212 (2015) PMID 25784990 PMCID PMC4358445

    The small-particle inhaled corticosteroid might be a new available way to treat uncontrolled asthma. To evaluate the efficacy and safety of extrafine hydrofluoroalkane-beclomethasone dipropionate (HFA-BDP) versus budesonide (BUD) in patients with asthma, a meta-analysis was performed. A systemat...
  13. Two new species of the acifer species group of Polypedilum subgenus Tripodura Townes from China (Diptera: Chironomidae).

    Zootaxa 3918(4):571 (2015) PMID 25781111

    Polypedilum (Tripodura) falcatum sp. n. and P. (T.) procerum sp. n. of the acifer species group of Polypedilum subgenus Tripodura Townes are described and illustrated as male imagines from China. The male adult of P. (T.) falcatum sp. n. is distinguished by the presence of two faint markings on ...
  14. Two histone/protein acetyltransferases, CBP and p300, are indispensable for Foxp3+ T-regulatory cell development and function.

    Molecular and Cellular Biology 34(21):3993 (2014) PMID 25154413 PMCID PMC4386456

    T-regulatory (Treg) cells are important to immune homeostasis, and Treg cell deficiency or dysfunction leads to autoimmune disease. A histone/protein acetyltransferase (HAT), p300, was recently found to be important for Treg function and stability, but further insights into the mechanisms by whi...
  15. A novel biomass assisted synthesis of Au-SrTiO3 as a catalyst for direct hydrogen generation from formaldehyde aqueous solution at low temperature

    International Journal of Hydrogen Energy (2014)

    A novel biomass-synthesized Au-SrTiO3 composite was prepared by syzygium extract and used for H2 evolution from formaldehyde aqueous solution without any additives at low temperature. The as-prepared catalyst exhibits the best performance for H2 evolution (111.15 μmol·g-1) compared wit...
  16. Novel microbial synthesis of Cu doped LaCoO3 photocatalyst and its high efficient hydrogen production from formaldehyde solution under visible light irradiation

    Fuel 140 (2014)

    • Cu doped LaCoO3 photocatalysts were prepared using microorganism Pichia pastoris GS115. • Cu and biomass residue display synergistic effect on enhancing the phot...
  17. Localization of protein kinase C isoforms in the optic pathway of mouse embryos and their role in axon routing at the optic chiasm.

    Brain research 1575:22 (2014) PMID 24863469

    Protein kinase C (PKC) plays a key role in many receptor-mediated signaling pathways that regulate cell growth and development. However, its roles in guiding axon growth and guidance in developing neural pathways are largely unknown. To investigate possible functions of PKC in the growth and gui...
  18. [Incidence of sudden cardiac death of urban residents in Beijing].

    Zhonghua xin xue guan bing za zhi [Chinese jour... 42(6):504 (2014) PMID 25164226

    To explore the incidence of sudden cardiac death (SCD) of urban residents in Beijing. A community based epidemiology survey was performed on the residents of 4 communities in the Xicheng and Haidian districts in Beijing from October 2008 to September 2009. Data on the total population, age, gend...
  19. A novel sulfur source for biosynthesis of (Ag, S)-modified TiO2photoanodes in DSSC

    Materials Letters 123:83 (2014)

    The (Ag, S)-modified TiO2 photoanodes were prepared using novel garlic (Allium sativum) as a sulfur source. X-ray photoelectron spectroscopy (XPS) confirmed more sulfur adsorption and the modification of TiO2 by interactions between Ag and S. UV–vis spectral analysis and Electrochemica...
  20. Heat shock protein 70 is required for optimal liver regeneration after partial hepatectomy in mice.

    Liver Transplantation and Surgery 20(3):376 (2014) PMID 24357103 PMCID PMC3947447

    Liver regeneration is a complex process that restores functional tissue after resection or injury, and it is accompanied by transient adenosine triphosphate depletion and metabolic stress in hepatic parenchymal cells. Heat shock protein 70 (Hsp70) functions as a chaperone during periods of cellu...