1. Persistent cat scratch disease requiring surgical excision in a patient with MPGN.

    Pediatrics 135(6):e1514 (2015) PMID 25963015

    We present the case of a 13-year-old immunosuppressed patient with unrelenting cat scratch disease despite 9 months of antibiotic therapy. The patient was being treated with mycophenolate and prednisone for membranoproliferative glomerulonephritis (type 1) diagnosed 13 months before the onset of...
  2. BCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children.

    Modern Pathology 28(4):575 (2015) PMID 25360585 PMCID PMC4385430

    The BCOR-CCNB3 fusion gene, resulting from a chromosome X paracentric inversion, was recently described in translocation-negative 'Ewing-like' sarcomas arising in bone and soft tissue. Genetic subclassification of undifferentiated unclassified sarcomas may potentially offer markers for reproduci...
  3. Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia.

    Circulation 131(8):730 (2015) PMID 25538227

    Preeclampsia is a prevalent hypertensive disorder of pregnancy and a leading cause of maternal and neonatal morbidity and mortality worldwide. This pathogenic condition is speculated to be caused by placental abnormalities that contribute to the maternal syndrome. However, the specific factors a...
  4. Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia.

    Circulation 131(8):730 (2015) PMID 25538227

    Preeclampsia is a prevalent hypertensive disorder of pregnancy and a leading cause of maternal and neonatal morbidity and mortality worldwide. This pathogenic condition is speculated to be caused by placental abnormalities that contribute to the maternal syndrome. However, the specific factors a...
  5. Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia.

    Circulation 131(8):730 (2015) PMID 25538227

    Preeclampsia is a prevalent hypertensive disorder of pregnancy and a leading cause of maternal and neonatal morbidity and mortality worldwide. This pathogenic condition is speculated to be caused by placental abnormalities that contribute to the maternal syndrome. However, the specific factors a...
  6. BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.

    Journal of Experimental Medicine 212(2):281 (2015) PMID 25646268 PMCID PMC4322054

  7. BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.

    Journal of Experimental Medicine 212(2):281 (2015) PMID 25646268 PMCID PMC4322054

  8. BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.

    Journal of Experimental Medicine 212(2):281 (2015) PMID 25646268 PMCID PMC4322054

  9. BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.

    Journal of Experimental Medicine 212(2):281 (2015) PMID 25646268

  10. Further Evidence that Human Acellular Dermal Matrix Decreases Inflammatory Markers of Capsule Formation in Implant-Based Breast Reconstruction.

    Aesthetic Surgery Journal 35(1):40 (2015) PMID 25568233

    Human acellular dermal matrix (HADM; previously termed "acellular cadaveric dermis") may limit inflammatory changes believed to play a role in capsular contracture, a common complication of implant-based breast reconstruction. Differences between HADM and native breast capsule specimens were eva...
  11. High titer anti-basement membrane antibodies in a subset of patients with pediatric systemic lupus erythematosus.

    American Journal of Nephrology 41(3):241 (2015) PMID 25926050 PMCID PMC4441865

    There is a critical need for more noninvasive biomarkers to identify nephritis in patients with systemic lupus erythematosus (SLE). Recent studies in a model mouse and an adult SLE patient cohort suggest that anti-basement membrane antibody levels correlate well with lupus activity and kidney in...
  12. Further evidence that human acellular dermal matrix decreases inflammatory markers of capsule formation in implant-based breast reconstruction.

    Aesthetic Surgery Journal 35(1):40 (2015) PMID 25568233

    Human acellular dermal matrix (HADM; previously termed "acellular cadaveric dermis") may limit inflammatory changes believed to play a role in capsular contracture, a common complication of implant-based breast reconstruction. Differences between HADM and native breast capsule specimens were eva...
  13. Further Evidence that Human Acellular Dermal Matrix Decreases Inflammatory Markers of Capsule Formation in Implant-Based Breast Reconstruction.

    Aesthetic Surgery Journal 35(1):40 (2015) PMID 25568233

    Human acellular dermal matrix (HADM; previously termed "acellular cadaveric dermis") may limit inflammatory changes believed to play a role in capsular contracture, a common complication of implant-based breast reconstruction. Differences between HADM and native breast capsule specimens were eva...
  14. Association of immunohistochemical markers with premalignancy in Gonadal Dysgenesis.

    International Journal of Pediatric Endocrinology 2015(1):14 (2015) PMID 26089923 PMCID PMC4472165

    Gonadal dysgenesis (GD) is associated with increased risk of gonadal malignancy. Determining a patient's risk and appropriate timing of gonadectomy is challenging, but immunohistochemical markers (IHM) may help establish the diagnosis of malignant germ cell tumors (GCT). Our objective was to ide...
  15. Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.

    Blood 124(19):3007 (2014) PMID 25202140 PMCID PMC4224195

    Langerhans cell histiocytosis (LCH) is a myeloproliferative disorder characterized by lesions composed of pathological CD207(+) dendritic cells with an inflammatory infiltrate. BRAFV600E remains the only recurrent mutation reported in LCH. In order to evaluate the spectrum of somatic mutations i...
  16. Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.

    Blood 124(19):3007 (2014) PMID 25202140 PMCID PMC4224195

    Langerhans cell histiocytosis (LCH) is a myeloproliferative disorder characterized by lesions composed of pathological CD207(+) dendritic cells with an inflammatory infiltrate. BRAFV600E remains the only recurrent mutation reported in LCH. In order to evaluate the spectrum of somatic mutations i...
  17. Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.

    Blood 124(19):3007 (2014) PMID 25202140 PMCID PMC4224195

    Langerhans cell histiocytosis (LCH) is a myeloproliferative disorder characterized by lesions composed of pathological CD207(+) dendritic cells with an inflammatory infiltrate. BRAFV600E remains the only recurrent mutation reported in LCH. In order to evaluate the spectrum of somatic mutations i...
  18. Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.

    Blood 124(19):3007 (2014) PMID 25202140 PMCID PMC4224195

    Langerhans cell histiocytosis (LCH) is a myeloproliferative disorder characterized by lesions composed of pathological CD207(+) dendritic cells with an inflammatory infiltrate. BRAFV600E remains the only recurrent mutation reported in LCH. In order to evaluate the spectrum of somatic mutations i...
  19. Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.

    Blood 124(19):3007 (2014) PMID 25202140 PMCID PMC4224195

    Langerhans cell histiocytosis (LCH) is a myeloproliferative disorder characterized by lesions composed of pathological CD207(+) dendritic cells with an inflammatory infiltrate. BRAFV600E remains the only recurrent mutation reported in LCH. In order to evaluate the spectrum of somatic mutations i...
  20. Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.

    Blood 124(19):3007 (2014) PMID 25202140 PMCID PMC4224195

    Langerhans cell histiocytosis (LCH) is a myeloproliferative disorder characterized by lesions composed of pathological CD207(+) dendritic cells with an inflammatory infiltrate. BRAFV600E remains the only recurrent mutation reported in LCH. In order to evaluate the spectrum of somatic mutations i...