1. Malignant T cells express lymphotoxin α and drive endothelial activation in cutaneous T cell lymphoma.

    Oncotarget 6(17):15235 (2015) PMID 25915535

    Lymphotoxin α (LTα) plays a key role in the formation of lymphatic vasculature and secondary lymphoid structures. Cutaneous T cell lymphoma (CTCL) is the most common primary lymphoma of the skin and in advanced stages, malignant T cells spreads through the lymphatic to regional lymph nodes to in...
  2. Ectopic expression of a novel CD22 splice-variant regulates survival and proliferation in malignant T cells from cutaneous T cell lymphoma (CTCL) patients.

    Oncotarget 6(16):14374 (2015) PMID 25957418

    CD22 is a member of the Sialic acid-binding Ig-like lectin (Siglec) family of lectins described to be exclusively present in B lymphocytes and B cell-derived neoplasms. Here, we describe a novel splice form of CD22 (designated CD22∆N), which lacks the N-terminal domain as demonstrated by exon-...
  3. IL-13 as a novel growth factor in CTCL.

    Blood 125(18):2737 (2015) PMID 25931576

  4. MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma.

    Anticancer Research 34(12):7207 (2014) PMID 25503151

    Mycosis fungoides (MF) is the most common variant of cutaneous T-cell lymphoma (CTCL). MF is characterized by chronic inflammation dominated by cluster of differentiation 4-positive (CD4(+)) T-cells and T helper 2 cytokines, and as the malignant T-cell clone is initially elusive, early diagnosis...
  5. MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma.

    Anticancer Research 34(12):7207 (2014) PMID 25503151

    Mycosis fungoides (MF) is the most common variant of cutaneous T-cell lymphoma (CTCL). MF is characterized by chronic inflammation dominated by cluster of differentiation 4-positive (CD4(+)) T-cells and T helper 2 cytokines, and as the malignant T-cell clone is initially elusive, early diagnosis...
  6. MicroRNA Expression in Early Mycosis Fungoides Is Distinctly Different from Atopic Dermatitis and Advanced Cutaneous T-Cell Lymphoma.

    Anticancer Research 34(12):7207 (2014) PMID 25503151

    Mycosis fungoides (MF) is the most common variant of cutaneous T-cell lymphoma (CTCL). MF is characterized by chronic inflammation dominated by cluster of differentiation 4-positive (CD4(+)) T-cells and T helper 2 cytokines, and as the malignant T-cell clone is initially elusive, early diagnosis...
  7. STAT3 activation and infiltration of eosinophil granulocytes in mycosis fungoides.

    Anticancer Research 34(10):5277 (2014) PMID 25275020

    Eosinophil granulocytes have been implicated in anticancer immunity but recent data indicate that eosinophils can also promote cancer. Herein, we studied eosinophils in skin lesions from 43 patients with mycosis fungoides (MF). The presence of eosinophils correlated with disease stage: 78% of pa...
  8. STAT3 activation and infiltration of eosinophil granulocytes in mycosis fungoides.

    Anticancer Research 34(10):5277 (2014) PMID 25275020

    Eosinophil granulocytes have been implicated in anticancer immunity but recent data indicate that eosinophils can also promote cancer. Herein, we studied eosinophils in skin lesions from 43 patients with mycosis fungoides (MF). The presence of eosinophils correlated with disease stage: 78% of pa...
  9. Intravascular large B cell lymphoma presenting as a thyroid mass.

    Endocrine Pathology 25(3):359 (2014) PMID 24014041

  10. Intravascular large B cell lymphoma presenting as a thyroid mass.

    Endocrine Pathology 25(3):359 (2014) PMID 24014041

  11. Staphylococcal enterotoxins stimulate lymphoma-associated immune dysregulation.

    Blood 124(5):761 (2014) PMID 24957145 PMCID PMC4118485

    Patients with cutaneous T-cell lymphoma (CTCL) are frequently colonized with Staphylococcus aureus (SA). Eradication of SA is, importantly, associated with significant clinical improvement, suggesting that SA promotes the disease activity, but the underlying mechanisms remain poorly characterize...
  12. Staphylococcal enterotoxins stimulate lymphoma-associated immune dysregulation.

    Blood 124(5):761 (2014) PMID 24957145 PMCID PMC4118485

    Patients with cutaneous T-cell lymphoma (CTCL) are frequently colonized with Staphylococcus aureus (SA). Eradication of SA is, importantly, associated with significant clinical improvement, suggesting that SA promotes the disease activity, but the underlying mechanisms remain poorly characterize...
  13. IL-15 and IL-17F are differentially regulated and expressed in mycosis fungoides (MF).

    Cell Cycle 13(8):1306 (2014) PMID 24621498 PMCID PMC4049967

    Skin lesions from mycosis fungoides (MF) patients display an increased expression of interleukin-15 (IL-15), IL-17F, and other cytokines implicated in inflammation and malignant cell proliferation in cutaneous T-cell lymphoma (CTCL). In the leukemic variant of CTCL, Sézary syndrome (SS), IL-2 an...
  14. Validation of a diagnostic microRNA classifier in cutaneous T-cell lymphomas.

    Leukemia & Lymphoma 55(4):957 (2014) PMID 23772646

  15. Validation of a diagnostic microRNA classifier in cutaneous T-cell lymphomas.

    Leukemia & Lymphoma 55(4):957 (2014) PMID 23772646

  16. Validation of a diagnostic microRNA classifier in cutaneous T-cell lymphomas.

    Leukemia & Lymphoma 55(4):957 (2014) PMID 23772646

  17. Development of lymphomas containing Epstein-Barr virus after therapy with hyper-CVAD regimen.

    Clinical Lymphoma Myeloma and Leukemia 14(2):e55 (2014) PMID 24393621

  18. Development of lymphomas containing Epstein-Barr virus after therapy with hyper-CVAD regimen.

    Clinical Lymphoma Myeloma and Leukemia 14(2):e55 (2014) PMID 24393621

  19. Cutaneous T cell lymphoma expresses immunosuppressive CD80 (B7-1) cell surface protein in a STAT5-dependent manner.

    Journal of Immunology 192(6):2913 (2014) PMID 24523507 PMCID PMC3984051

    In this article, we report that cutaneous T cell lymphoma (CTCL) cells and tissues ubiquitously express the immunosuppressive cell surface protein CD80 (B7-1). CD80 expression in CTCL cells is strictly dependent on the expression of both members of the STAT5 family, STAT5a and STAT5b, as well as...
  20. Cutaneous T cell lymphoma expresses immunosuppressive CD80 (B7-1) cell surface protein in a STAT5-dependent manner.

    Journal of Immunology 192(6):2913 (2014) PMID 24523507 PMCID PMC3984051

    In this article, we report that cutaneous T cell lymphoma (CTCL) cells and tissues ubiquitously express the immunosuppressive cell surface protein CD80 (B7-1). CD80 expression in CTCL cells is strictly dependent on the expression of both members of the STAT5 family, STAT5a and STAT5b, as well as...