1. Maternal immune activation and abnormal brain development across CNS disorders.

    Nature Clinical Practice Neurology 10(11):643 (2014) PMID 25311587

    Epidemiological studies have shown a clear association between maternal infection and schizophrenia or autism in the progeny. Animal models have revealed maternal immune activation (mIA) to be a profound risk factor for neurochemical and behavioural abnormalities in the offspring. Microglial pri...
  2. Maternal immune activation and abnormal brain development across CNS disorders.

    Nature Clinical Practice Neurology 10(11):643 (2014) PMID 25311587

    Epidemiological studies have shown a clear association between maternal infection and schizophrenia or autism in the progeny. Animal models have revealed maternal immune activation (mIA) to be a profound risk factor for neurochemical and behavioural abnormalities in the offspring. Microglial pri...
  3. Mind the gut: secretion of α-synuclein by enteric neurons.

    Journal of Neurochemistry 125(4):487 (2013) PMID 23448303

  4. Mind the gut: secretion of α-synuclein by enteric neurons.

    Journal of Neurochemistry 125(4):487 (2013) PMID 23448303

  5. Inflammation and α-synuclein's prion-like behavior in Parkinson's disease--is there a link?

    Molecular Neurobiology 47(2):561 (2013) PMID 22544647 PMCID PMC3589652

    Parkinson's disease patients exhibit progressive spreading of aggregated α-synuclein in the nervous system. This slow process follows a specific pattern in an inflamed tissue environment. Recent research suggests that prion-like mechanisms contribute to the propagation of α-synuclein pathology. ...
  6. Inflammation and α-synuclein's prion-like behavior in Parkinson's disease--is there a link?

    Molecular Neurobiology 47(2):561 (2013) PMID 22544647 PMCID PMC3589652

    Parkinson's disease patients exhibit progressive spreading of aggregated α-synuclein in the nervous system. This slow process follows a specific pattern in an inflamed tissue environment. Recent research suggests that prion-like mechanisms contribute to the propagation of α-synuclein pathology. ...
  7. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  8. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  9. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  10. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  11. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  12. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  13. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  14. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  15. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  16. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  17. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  18. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  19. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...
  20. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

    Journal of Experimental Medicine 210(1):157 (2013) PMID 23296467 PMCID PMC3549715

    Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse...