1. Enhanced methane production via repeated batch bioaugmentation pattern of enriched microbial consortia.

    Bioresource Technology 216:471 (2016) PMID 27262722

    Using batch and repeated batch cultivations, this study investigated the effects of bioaugmentation with enriched microbial consortia (named as EMC) on methane production from effluents of hydrogen-producing stage of potato slurry, as well as on the indigenous bacterial community. The results de...
  2. Circulating Prolactin and Risk of Type 2 Diabetes: A Prospective Study.

    American Journal of Epidemiology 184(4):295 (2016) PMID 27466075

    Prolactin plays an important role in maintaining a normal glucose homeostasis during pregnancy and beyond. Studies investigating the association between prolactin and type 2 diabetes beyond pregnancy are rare and none is prospective. We aimed to examine whether prolactin associates with type 2 d...
  3. mTORC1 promotes aging-related venous thrombosis in mice via elevation of platelet volume and activation.

    Blood 128(5):615 (2016) PMID 27288518

    Aging is associated with an increased incidence of venous thromboembolism (VTE), resulting in significant morbidity and mortality in the elderly. Platelet hyperactivation is linked to aging-related VTE. However, the mechanisms through which aging enhances platelet activation and susceptibility t...
  4. Bioaugmentation of Hydrogenispora ethanolica LX-B affects hydrogen production through altering indigenous bacterial community structure.

    Bioresource Technology 211:319 (2016) PMID 27023388

    Bioaugmentation can facilitate hydrogen production from complex organic substrates, but it still is unknown how indigenous microbial communities respond to the added bacteria. Here, using a Hydrogenispora ethanolica LX-B (named as LX-B) bioaugmentation experiments, the distribution of metabolite...
  5. Plasma glucose and hemoglobin A1c for the detection of diabetes in Chinese adults.

    Journal Of Diabetes 8(3):378 (2016) PMID 25940519

    The aim of the present study was to evaluate the performance of plasma glucose (PG) and HbA1c for the detection of diabetes in the general population in China. A cross-sectional analysis was conducted in a nationally representative sample of 98,658 Chinese adults aged ≥18 years. Fasting plasma g...
  6. Association between the change in body mass index from early adulthood to midlife and subsequent type 2 diabetes mellitus.

    Obesity 24(3):703 (2016) PMID 26833544

    To clarify the quantitative relationship of body mass index (BMI) change from early adulthood to midlife with presence of type 2 diabetes mellitus (T2DM) after midlife. This study included 120,666 middle-aged and elderly, whose retrospectively self-reported body weight at 20 and 40 years and mea...
  7. [Study based on sonoelastography technology for spastic gastrocnemius in rat with spinal cord injure].

    Zhonghua Yixue Zazhi 96(5):364 (2016) PMID 26875717

    To investigate the pathological characteristic of gastrocnemius (GM) and quantitatively assess GM tissue stiffness in spinal cord injury (SCI) rat models; to explore the novel method in evaluation of GM stiffness. A total of 54 SD male rats (weight 260-280 g) were allocated into normal control g...
  8. Diabetes-related metabolic risk factors in internal migrant workers in China: a national surveillance study.

    The lancet. Diabetes & endocrinology 4(2):125 (2016) PMID 26776861

    Little is known about the cardiometabolic health of internal migrant workers in China. We aimed to examine the prevalence of diabetes-related cardiometabolic risk factors in this large, but little-studied population. We did this national surveillance study within the Chinese Center for Disease C...
  9. MicroRNA-130b promotes lung cancer progression via PPARγ/VEGF-A/BCL-2-mediated suppression of apoptosis.

    Journal of Experimental & Clinical Cancer Research 35(1):105 (2016) PMID 27364335 PMCID PMC4929777

    The prognosis of non-small-cell lung cancer (NSCLC) is poor yet mechanistic understanding and therapeutic options remain limited. We investigated the biological and clinical significance of microRNA-130b and its relationship with apoptosis in NSCLC. The level of microRNA-130b in relationship wit...
  10. Diabetes Genetic Risk Score Modifies Effect of Bisphenol A Exposure on Deterioration in Glucose Metabolism.

    Journal of Clinical Endocrinology & Metabolism 101(1):143 (2016) PMID 26523527

    Epidemiology studies showed inconsistent results regarding the relationship between bisphenol A (BPA) exposure and risk of type 2 diabetes (T2D). This study sought to prospectively investigate associations of BPA with incident T2D risk and the longitudinal changes in glycemic traits, particularl...
  11. Reduced Kidney Function Is Associated With Cardiometabolic Risk Factors, Prevalent and Predicted Risk of Cardiovascular Disease in Chinese Adults: Results From the REACTION Study.

    Journal of the American Heart Association Cardi... 5(7) (2016) PMID 27451464

    Chronic kidney disease (CKD) increases cardiovascular disease (CVD) risk. However, the association of mildly reduced kidney function with CVD risk is unclear. This study investigated the association of estimated glomerular filtration rate (eGFR) with prevalent CVDs, 10-year Framingham risk for c...
  12. Identification of novel genes and pathways in carotid atheroma using integrated bioinformatic methods.

    Scientific reports 6:18764 (2016) PMID 26742467 PMCID PMC4705461

    Atherosclerosis is the primary cause of cardiovascular events and its molecular mechanism urgently needs to be clarified. In our study, atheromatous plaques (ATH) and macroscopically intact tissue (MIT) sampled from 32 patients were compared and an integrated series of bioinformatic microarray a...
  13. The chemical properties and microbial community characterization of the thermophilic microaerobic pretreatment process.

    Bioresource Technology 198:497 (2015) PMID 26433149

    Thermophilic microaerobic pretreatment (TMP) was recently reported as an efficient pretreatment method of anaerobic digestion (AD). In this study, the chemical properties and microbial community were characterized to reveal how TMP working. Compared with thermophilic treatment under anaerobic co...
  14. BPTF promotes tumor growth and predicts poor prognosis in lung adenocarcinomas.

    Oncotarget 6(32):33878 (2015) PMID 26418899 PMCID PMC4741809

    BPTF, a subunit of NURF, is well known to be involved in the development of eukaryotic cell, but little is known about its roles in cancers, especially in non-small-cell lung cancer (NSCLC). Here we showed that BPTF was specifically overexpressed in NSCLC cell lines and lung adenocarcinoma tissu...
  15. Prevalence and trends in overweight and obesity among Chinese adults in 2004–10: data from three nationwide surveys in China

    The Lancet 386:S77 (2015)

    Background Obesity has become a global epidemic and is a common risk factor for many chronic diseases. Few data for the prevalence and trends in overweight and obesity in Chinese adults have been obtained over the past decade. We aimed to estimate changes in the prevalence of...
  16. Overexpression of Lysine-Specific Demethylase 1 Is Associated With Tumor Progression and Unfavorable Prognosis in Chinese Patients With Endometrioid Endometrial Adenocarcinoma.

    International Journal of Gynecological Cancer 25(8):1453 (2015) PMID 26166558

    Lysine-specific demethylase 1 (LSD1) is a kind of flavin adenine dinucleotide-dependent amine oxidase that regulates normal cellular differentiation, gene activation, tumorigenesis, and progression. This study aims to detect the expression level of LSD1 in endometrial cancer and to explore its r...
  17. Diabetes genetic score, diabetes, and arterial stiffness: a Mendelian randomisation analysis in Chinese

    The Lancet 386:S53 (2015)

    Background The nature and underlying mechanisms of the association between type 2 diabetes and the risk of increased arterial stiffness are unclear. We aimed to study this association using the Mendelian randomisation approach.
  18. RFPL3 and CBP synergistically upregulate hTERT activity and promote lung cancer growth.

    Oncotarget 6(29):27130 (2015) PMID 26318425 PMCID PMC4694978

    hTERT is the key component of telomerase and its overactivation contributes to maintaining telomere length and cell immortalization. Previously, we identified RFPL3 as a new transcription activator of hTERT in lung cancers. However, the exact mechanism of RFPL3 in mediating hTERT activation and ...
  19. Serum Fetuin-A Associated With Fatty Liver Index, Early Indicator of Nonalcoholic Fatty Liver Disease: A Strobe-Compliant Article.

    Medicine (Baltimore) 94(39):e1517 (2015) PMID 26426614 PMCID PMC4616834

    Increased fetuin-A has been reported in association with type 2 diabetes and other metabolic diseases. However, the large population data concerning fetuin-A and nonalcoholic fatty liver disease (NAFLD) were limited. In this study, we aimed to investigate the association of serum fetuin-A with f...
  20. Secondary thermophilic microaerobic treatment in the anaerobic digestion of corn straw.

    Bioresource Technology 186:321 (2015) PMID 25818257

    Thermophilic microaerobic pretreatment (TMP) has been proved to be an alternative pretreatment method during anaerobic digestion (AD) of corn straw. In this study, in order to improve the fermentation efficiency during late AD stage, improve the methane yield and volatile solid (VS) removal effi...