1. Total arterial compliance estimated by a novel method and all-cause mortality in the elderly: the PROTEGER study.

    Age 36(3):9661 (2014) PMID 24801452 PMCID PMC4082579

    Aortic stiffness, assessed by carotid-to-femoral pulse wave velocity (PWV), often fails to predict cardiovascular (CV) risk and mortality in the very elderly. This may be due to the non-linear association between PWV and compliance or to blood pressure decrease in the frailest subjects. Total ar...
  2. 0360: Increased stiffness and cell-matrix interactions of abdominal aorta in two experimental non-hypertensive models: long-term chemical sympathectomized and sinoaortic-denervated rats

    Archives of Cardiovascular Diseases Supplements 6:55 (2014)

    Sinoaortic denervated (SAD) and chemically sympathectomized (SNX) rats are characterized by a decrease in arterial distensibility without hypertension and would thus be relevant for analyzing arterial wall stiffening independently of blood pressure level. The fibronectin network, which...
  3. 0372: Partial adherence to antihypertensive therapy increases long-term blood pressure variability and fails to improve aortic stiffness in SHR rat

    Archives of Cardiovascular Diseases Supplements 6:56 (2014)

    Poor adherence to antihypertensive therapy and long-term blood pressure variability are 2 major contributors to cardiovascular damage. However, the determinants of increased long-term blood pressure variability remained scattered and incomplete. We hypothesized that intermittent treatm...
  4. Blood pressure control with a single-pill combination of indapamide sustained-release and amlodipine in patients with hypertension: the EFFICIENT study.

    PLoS ONE 9(4):e92955 (2014) PMID 24714044 PMCID PMC3979648

    Despite antihypertensive treatment, most hypertensive patients still have high blood pressure (BP), notably high systolic blood pressure (SBP). The EFFICIENT study examines the efficacy and acceptability of a single-pill combination of sustained-release (SR) indapamide, a thiazide-like diuretic,...
  5. Elderly Algerian women lose their sex-advantage in terms of arterial stiffness and cardiovascular profile.

    Journal of Hypertension 31(11):2244 (2013) PMID 23812000

    Several studies have shown lower carotid-femoral pulse wave velocity (cfPWV) levels in women compared to men, a difference that could partially explain the increased longevity in women. However, these studies have been performed in industrial countries while few data are available in emerging po...
  6. Le JNC 8 est sorti… mais ce n’est pas le JNC 8 ! Nouvelles recommandations américaines pour la prise en charge de l’hypertension artérielle

    PANORAMA DU M�DECIN 43(10) (2013) PMID 25201593

    L’année 2013 a vu la publication de plusieurs recommandations pour la prise en charge de l’HTA : des recommandations françaises, européennes, et deux recommandations américaines, celles de l’ACC/AHA/CDC et celles du JNC 8. Les recommandations du JNC 8 ne sont pas, à propremen...
  7. [Orthostatic hypotension: marker of severity and management of antihypertensive treatment].

    PANORAMA DU M�DECIN 41(11):1116 (2012) PMID 22480861

    Orthostatic Hypotension (OH) is an independent predictor of cardiovascular disease and of all-cause mortality. It is a marker of poor prognosis in older and middle-aged patients. It should be primarily sought, at diagnosis of hypertension, at therapeutic modification, and when suspected by sympt...
  8. [Visit-to-visit variability: Prognostic significance?].

    PANORAMA DU M�DECIN 41(6 Pt 1):650 (2012) PMID 22498102

    Hypertension is the most prevalent treatable risk factor for stroke. Treatment of hypertension is based on usual blood pressure, which is evaluated by repeated measurement. When only few measurements show high blood pressure, this is considered as a background noise generally due to white coat e...
  9. Cardiovascular and renal outcome in recipients of kidney grafts from living donors: role of aortic stiffness.

    Nephrology Dialysis Transplantation 27(5):2095 (2012) PMID 21980156

    Cardiovascular (CV) risk remains high in renal transplant patients despite a clear improvement conferred by transplantation. This risk is attributed mostly to recipient-related risk factors. Donor vascular characteristics, such as arterial stiffness, have been poorly investigated in this regard....
  10. [Tropical aortitis].

    PANORAMA DU M�DECIN 41(1):74 (2012) PMID 21981880

  11. Changes in the Central Arterial Pressure Pulse With Aging

    Journal of the American College of Cardiology 55(19):2183 (2010) PMID 20447548

  12. Changes in the Central Arterial Pressure Pulse With Aging

    Journal of the American College of Cardiology 55(19):2183 (2010) PMID 20447548

  13. Differential associations of dietary sodium and potassium intake with blood pressure: a focus on pulse pressure.

    Journal of Hypertension 27(6):1158 (2009) PMID 19462490

    Dietary sodium and potassium intakes are factors known to influence blood pressure (BP) through different pathways. These mechanisms likely result in differential effects on parameters characterizing BP. The aim of the study was to evaluate relationships between both sodium and potassium intake ...
  14. Can ambulatory blood-pressure monitoring provide reliable indices of arterial stiffness?

    American Journal of Hypertension 20(8):831 (2007) PMID 17679028

    The use of ambulatory recordings of blood pressure (BP) was proposed to estimate arterial stiffness (AS). We compared the relative value of the ambulatory AS index (AASI), and of the slope of pulse pressure (PP) according to mean BP (MBP) obtained from 24-h ambulatory BP monitoring, to the monit...
  15. Prevention of stroke and myocardial infarction by amlodipine and Angiotensin receptor blockers: a quantitative overview.

    Hypertension 50(1):181 (2007) PMID 17502490

    In the present quantitative overview of outcome trials, we investigated the efficacy of amlodipine or angiotensin receptor blockers in the prevention of stroke and myocardial infarction in patients with hypertension, coronary artery disease, or diabetic nephropathy. The analysis included 12 tria...
  16. Can Ambulatory Blood-Pressure Monitoring Provide Reliable Indices of Arterial Stiffness?

    American Journal of Hypertension 20(8):831 (2007)

    Background The use of ambulatory recordings of blood pressure (BP) was proposed to estimate arterial stiffness (AS). We compared the relative value of the ambulatory AS index (AASI), and of the slope of pulse pressure (PP) according to mean BP (MBP) obtained from 24-h ambulatory BP mon...
  17. Carotid intima-media thickness and antihypertensive treatment: a meta-analysis of randomized controlled trials.

    Stroke 37(7):1933 (2006) PMID 16763185

    Hypertension promotes carotid intima-media thickening. We reviewed the randomized controlled trials that evaluated the effects of an antihypertensive drug versus placebo or another antihypertensive agent of a different class on carotid intima-media thickness. We searched the PubMed and the Web o...
  18. Increased skin capillary density in treated essential hypertensive patients.

    American Journal of Hypertension 19(5):477 (2006) PMID 16647618

    Microvascular rarefaction is a hallmark of essential hypertension. We measured the skin capillary density in nondiabetic hypertensive subjects with effective antihypertensive treatment and evaluated possible correlations with arterial blood pressure (BP). This cross-sectional observational study...
  19. Increased Skin Capillary Density in Treated Essential Hypertensive Patients

    American Journal of Hypertension 19(5):477 (2006)

    Background Microvascular rarefaction is a hallmark of essential hypertension. We measured the skin capillary density in nondiabetic hypertensive subjects with effective antihypertensive treatment and evaluated possible correlations with arterial blood pressure (BP).
  20. Early activation of internal medial smooth muscle cells in the rabbit aorta after mechanical injury: relationship with intimal thickening and pharmacological applications.

    Clinical and Experimental Pharmacology and Phys... 33(1-2):131 (2006) PMID 16445712

    1. Smooth muscle cells (SMC) participate in both inflammatory and dedifferentiation processes during atherosclerosis, as well as during mechanical injury following angioplasty. In the latter, we studied medial SMC differentiation and inflammation processes implicated early after de-endothelializ...