1. Multidrug-resistant tuberculosis: Treatment and outcomes of 93 patients.

    Canadian respiratory journal : journal of the C... 22(2):97 (2015) PMID 25493698 PMCID PMC4390019

    Tuberculosis (TB) remains a leading cause of death worldwide and the emergence of multidrug-resistant TB (MDR TB) poses a threat to its control. There is scanty evidence regarding optimal management of MDR TB. The majority of Canadian cases of MDR TB are diagnosed in Ontario; most are managed by...
  2. Family caregiver perspectives on caring for ventilator-assisted individuals at home.

    Canadian respiratory journal : journal of the C... 19(6):373 (2012) PMID 23248801 PMCID PMC3603762

    The trend of patients who are invasively ventilated to prefer home care is one that benefits both the patient and the health care system. However, this assumes a role for patients' family members to become informal caregivers. To explore the impact of caring for a ventilator-assisted individual ...
  3. Home mechanical ventilation: a Canadian Thoracic Society clinical practice guideline.

    Canadian respiratory journal : journal of the C... 18(4):197 (2011) PMID 22059178 PMCID PMC3205101

    Increasing numbers of patients are surviving episodes of prolonged mechanical ventilation or benefitting from the recent availability of userfriendly noninvasive ventilators. Although many publications pertaining to specific aspects of home mechanical ventilation (HMV) exist, very few comprehens...
  4. Central nervous system tuberculous abscess.

    European Journal of Internal Medicine 18(6):504 (2007) PMID 17822664

    Central nervous system tuberculosis (CNS TB), uncommon in developed countries, still constitutes a significant proportion of brain mass lesions in developing countries. With the consistent increase in TB in the third world and the increase in immigration to Western countries, we can also expect ...
  5. [Pulmonary and nonpulmonary alterations in Duchenne muscular dystrophy].

    Archivos de Bronconeumología 43(10):557 (2007) PMID 17939910

    To describe our experience in managing patients with Duchenne muscular dystrophy. We analyzed the following variables in a group of 27 patients with Duchenne muscular dystrophy: arterial blood gases, lung function before and after mechanical ventilation, oxygen saturation (measured by pulse oxim...
  6. One-year outcomes and health care utilization in survivors of severe acute respiratory syndrome.

    Archives of Internal Medicine 167(12):1312 (2007) PMID 17592106

    Severe Acute Respiratory Syndrome (SARS) became a global epidemic in 2003. Comprehensive information on 1-year outcomes and health care utilization is lacking. Research conducted during the SARS outbreak may help inform research planning for future public health emergencies. The objective of thi...
  7. Alteraciones pulmonares y no pulmonares en la distrofia muscular de Duchenne

    Archivos de Bronconeumología 43(10):557 (2007)

    Objetivo Describir nuestra experiencia en el manejo de pacientes con distrofia muscular de Duchenne (DMD).
  8. Pulmonary and Nonpulmonary Alterations in Duchenne Muscular Dystrophy

    Archivos de Bronconeumología (English Edition) 43(10):557 (2007)

    Objective To describe our experience in managing patients with Duchenne muscular dystrophy.
  9. Central nervous system tuberculous abscess

    European Journal of Internal Medicine 18(6):504 (2007)

    Central nervous system tuberculosis (CNS TB), uncommon in developed countries, still constitutes a significant proportion of brain mass lesions in developing countries. With the consistent increase in TB in the third world and the increase in immigration to Western countries, we can also ex...
  10. Papular acantholytic dyskeratosis of the vulva.

    Pediatric Dermatology 22(3):237 (2005) PMID 15916573

    We describe an 11-year-old girl with a persistent pruritic papular eruption on the vulva. Clinically, the lesions consisted of whitish papules and erosions located on the inner aspect of the labia majora. There was no familial history of skin diseases. Histologically, a biopsy specimen showed di...
  11. Chest radiographic manifestations of severe acute respiratory syndrome in health care workers: the Toronto experience.

    American Journal of Roentgenology 182(1):45 (2004) PMID 14684510

    The purpose of this article is to describe the chest radiographic manifestations of severe acute respiratory syndrome (SARS) in previously uninfected health care workers during the early stages of an outbreak in Toronto, Canada. The study group was composed of 13 patients from a single instituti...
  12. Tuberculosis among Tibetan refugee claimants in Toronto: 1998 to 2000.

    Chest 124(3):915 (2003) PMID 12970017

    Between 1998 and 2000, approximately 525 Tibetan people previously living in the United States claimed refugee status in Canada, many of whom were referred to our centers for completion of tuberculosis (TB) screening. We reviewed TB-related outcomes in this cohort, to compare our experience with...
  13. Clinical course and management of SARS in health care workers in Toronto: a case series.

    Canadian Medical Association Journal 168(13):1649 (2003) PMID 12821618 PMCID PMC161610

    Severe acute respiratory syndrome (SARS) has only recently been described. We provide individual patient data on the clinical course, treatment and complications experienced by 14 front-line health care workers and hospital support staff in Toronto who were diagnosed with SARS, and we provide fo...
  14. Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area.

    JAMA 289(21):2801 (2003) PMID 12734147

    Severe acute respiratory syndrome (SARS) is an emerging infectious disease that first manifested in humans in China in November 2002 and has subsequently spread worldwide. To describe the clinical characteristics and short-term outcomes of SARS in the first large group of patients in North Ameri...
  15. Long term follow-up of ventilated patients with thoracic restrictive or neuromuscular disease.

    Canadian respiratory journal : journal of the C... 9(2):99 (2002) PMID 11972163

    To evaluate the long term effects of home mechanical ventilation (HMV) on pulmonary function, nighttime gas exchange, daytime arterial blood gases, sleep architecture and functional exercise capacity (6 min walk). Patients with respiratory failure attributable to thoracic restrictive disease (TR...
  16. Predictors of functioning of patients with chronic obstructive pulmonary disease

    Heart & Lung: The Journal of Acute and Critical... 24(5):369 (1995)

    Objective To determine the extent to which mood, symptoms, lung functions, and social support of patients with chronic obstructive pulmonary disease (COPD) predicted their level of functioning over a 30-month period. Design Prospective, longitudinal. ...