1. In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides.

    Journal of Hepatology 64(4):781 (2016) PMID 26658683

    Current treatment of chronic hepatitis B virus infection (CHB) includes interferon and nucleos(t)ide analogues, which generally do not reduce HBV surface antigen (HBsAg) production, a constellation that is associated with poor prognosis of CHB. Here we evaluated the efficacy of an antisense appr...
  2. Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model.

    Nature Communications 6:7339 (2015) PMID 26081744 PMCID PMC4557302

    Diseases of lipid metabolism are a major cause of human morbidity, but no animal model entirely recapitulates human lipoprotein metabolism. Here we develop a xenograft mouse model using hepatocytes from a patient with familial hypercholesterolaemia caused by loss-of-function mutations in the low...
  3. Clinical outcomes of hepatitis B virus coinfection in a United States cohort of hepatitis C virus-infected patients.

    Hepatology 60(6):1871 (2014) PMID 25065513 PMCID PMC4245372

    The effect of hepatitis B virus (HBV) coinfection in patients with hepatitis C virus (HCV) remains unclear. We used the National Veterans Affairs HCV Clinical Case Registry to identify patients with confirmed HCV viremia during 1997-2005. We defined HBV coinfection as a positive test for hepatit...
  4. Medium-term results of total knee arthroplasty using a medially pivoting implant: a multicenter study.

    Journal of surgical orthopaedic advances 19(4):191 (2010) PMID 21244804

    A multicenter study was conducted to determine the durability and performance of a medially pivoting knee prosthesis in total knee arthroplasty (TKA). Between February 1999 and June 2001, 276 patients underwent 298 primary TKAs at five centers. There were 189 patients (204 knees) available for c...
  5. Identities satisfied by a finite ring

    Journal of Algebra 26(2):298 (1973)

  6. A normality relation for lattices

    Journal of Algebra 3(3):277 (1966)