1. Social evolution. Genomic signatures of evolutionary transitions from solitary to group living.

    Science 348(6239):1139 (2015) PMID 25977371

    The evolution of eusociality is one of the major transitions in evolution, but the underlying genomic changes are unknown. We compared the genomes of 10 bee species that vary in social complexity, representing multiple independent transitions in social evolution, and report three major findings....
  2. A Massive Expansion of Effector Genes Underlies Gall-Formation in the Wheat Pest Mayetiola destructor.

    Current Biology 25(5):613 (2015) PMID 25660540

    Gall-forming arthropods are highly specialized herbivores that, in combination with their hosts, produce extended phenotypes with unique morphologies [1]. Many are economically important, and others have improved our understanding of ecology and adaptive radiation [2]. However, the mechanisms th...
  3. Mosquito biology. Evolution of sexual traits influencing vectorial capacity in anopheline mosquitoes.

    Science 347(6225):985 (2015) PMID 25722409

    The availability of genome sequences from 16 anopheline species provides unprecedented opportunities to study the evolution of reproductive traits relevant for malaria transmission. In Anopheles gambiae, a likely candidate for sexual selection is male 20-hydroxyecdysone (20E). Sexual transfer of...
  4. Mosquito biology. Evolution of sexual traits influencing vectorial capacity in anopheline mosquitoes.

    Science 347(6225):985 (2015) PMID 25722409 PMCID PMC4373528

    The availability of genome sequences from 16 anopheline species provides unprecedented opportunities to study the evolution of reproductive traits relevant for malaria transmission. In Anopheles gambiae, a likely candidate for sexual selection is male 20-hydroxyecdysone (20E). Sexual transfer of...
  5. OrthoDB v8: update of the hierarchical catalog of orthologs and the underlying free software.

    Nucleic Acids Research 43(Database issue):D250 (2015) PMID 25428351

    Orthology, refining the concept of homology, is the cornerstone of evolutionary comparative studies. With the ever-increasing availability of genomic data, inference of orthology has become instrumental for generating hypotheses about gene functions crucial to many studies. This update of the Or...
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  6. Mosquito genomics. Extensive introgression in a malaria vector species complex revealed by phylogenomics.

    Science 347(6217):1258524 (2015) PMID 25431491

    Introgressive hybridization is now recognized as a widespread phenomenon, but its role in evolution remains contested. Here, we use newly available reference genome assemblies to investigate phylogenetic relationships and introgression in a medically important group of Afrotropical mosquito sibl...
  7. Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes.
    Daniel E Neafsey, Robert M Waterhouse, Mohammad R Abai, Sergey Aganezov, Max Alekseyev, James E Allen, James Amon, Bruno Arcà, Peter Arensburger, Gleb Artemov, Lauren Assour, Hamidreza Basseri, Aaron Berlin, Bruce W Birren, Stephanie A Blandin, Andrew I Brockman, Thomas R Burkot, Austin Burt, Clara S Chan, Cedric Chauve, Joanna Chiu, Mikkel Christensen, Carlo Costantini, Victoria L M Davidson, Elena Deligianni, Tania Dottorini, Vicky Dritsou, Stacey B Gabriel, Wamdaogo M Guelbeogo, Andrew B Hall, Mira V Han, Thaung Hlaing, Daniel S T Hughes, Adam M Jenkins, Xiaofang Jiang, Irwin Jungreis, Evdoxia G Kakani, Maryam Kamali, Petri Kemppainen, Ryan C Kennedy, Ioannis Kirmitzoglou, Lizette Koekemoer, Njoroge Laban, Nicholas Langridge, Mara K N Lawniczak, Manolis Lirakis, Neil F Lobo, Ernesto Lowy, Robert MacCallum, Chunhong Mao, Gareth Maslen, Charles Mbogo, Jenny McCarthy, Kristin Michel, Sara N Mitchell, Wendy Moore, Katherine A Murphy, Anastasia Naumenko, Tony Nolan, Eva M Novoa, Samantha O'Loughlin, Chioma Oringanje, Mohammad A Oshaghi, Nazzy Pakpour, Philippos A Papathanos, Ashley N Peery, Michael Povelones, Anil Prakash, David Price, Ashok Rajaraman, Lisa J Reimer, David C Rinker, Antonis Rokas, Tanya L Russell, N'Fale Sagnon, Maria V Sharakhova, Terrance Shea, Felipe A Simão, Frederic Simard, Michel A Slotman, Pradya Somboon, Vladimir Stegniy, Claudio J Struchiner, Gregg W C Thomas, Marta Tojo, Pantelis Topalis, José M C Tubio, Maria F Unger, John Vontas, Catherine Walton, Craig S Wilding, Judith H Willis, Yi-Chieh Wu, Guiyun Yan, Evgeny M Zdobnov, Xiaofan Zhou, Flaminia Catteruccia, George K Christophides, Frank H Collins, Robert S Cornman, Andrea Crisanti, Martin J Donnelly, Scott J Emrich, Michael C Fontaine, William Gelbart, Matthew W Hahn, Immo A Hansen, Paul I Howell, Fotis C Kafatos, Manolis Kellis, Daniel Lawson, Christos Louis, Shirley Luckhart, Marc A T Muskavitch, José M Ribeiro, Michael A Riehle, Igor V Sharakhov, Zhijian Tu, Laurence J Zwiebel, and Nora J Besansky

    Science 347(6217):1258522 (2015) PMID 25554792

    Variation in vectorial capacity for human malaria among Anopheles mosquito species is determined by many factors, including behavior, immunity, and life history. To investigate the genomic basis of vectorial capacity and explore new avenues for vector control, we sequenced the genomes of 16 anop...
  8. OrthoDB v8: update of the hierarchical catalog of orthologs and the underlying free software.

    Nucleic Acids Research 43(Database issue):D250 (2015) PMID 25428351 PMCID PMC4383991

    Orthology, refining the concept of homology, is the cornerstone of evolutionary comparative studies. With the ever-increasing availability of genomic data, inference of orthology has become instrumental for generating hypotheses about gene functions crucial to many studies. This update of the Or...
  9. A depauperate immune repertoire precedes evolution of sociality in bees.

    Genome biology 16(1):83 (2015) PMID 25908406 PMCID PMC4408586

    Sociality has many rewards, but can also be dangerous, as high population density and low genetic diversity, common in social insects, is ideal for parasite transmission. Despite this risk, honeybees and other sequenced social insects have far fewer canonical immune genes relative to solitary in...
  10. OrthoDB v8: update of the hierarchical catalog of orthologs and the underlying free software.

    Nucleic Acids Research 43(Database issue):D250 (2015) PMID 25428351

    Orthology, refining the concept of homology, is the cornerstone of evolutionary comparative studies. With the ever-increasing availability of genomic data, inference of orthology has become instrumental for generating hypotheses about gene functions crucial to many studies. This update of the Or...
    PDF not found
  11. The genomes of two key bumblebee species with primitive eusocial organization.
    Ben M Sadd, Seth M Barribeau, Guy Bloch, Dirk C de Graaf, Peter Dearden, Christine G Elsik, Jürgen Gadau, Cornelis J P Grimmelikhuijzen, Martin Hasselmann, Jeffrey D Lozier, Hugh M Robertson, Guy Smagghe, Eckart Stolle, Matthias Van Vaerenbergh, Robert M Waterhouse, Erich, Steffen Klasberg, Anna K Bennett, Francisco Câmara, Roderic Guigó, Katharina Hoff, Marco Mariotti, Monica Munoz-Torres, Terence Murphy, Didac Santesmasses, Gro V Amdam, Matthew Beckers, Martin Beye, Matthias Biewer, Márcia G Bitondi, Mark L Blaxter, Andrew F G Bourke, Mark J F Brown, Severine D Buechel, Rossanah Cameron, Kaat Cappelle, James Carolan, Olivier Christiaens, Kate L Ciborowski, David F Clarke, Thomas J Colgan, David H Collins, Andrew G Cridge, Tamas Dalmay, Stephanie Dreier, Louis du Plessis, Elizabeth Duncan, Silvio Erler, Jay Evans, Tiago Falcon, Kevin Flores, Flávia C P Freitas, Taro Fuchikawa, Tanja Gempe, Klaus Hartfelder, Frank Hauser, Sophie Helbing, Fernanda C Humann, Frano Irvine, Lars S Jermiin, Claire E Johnson, Reed M Johnson, Andrew K Jones, Tatsuhiko Kadowaki, Jonathan H Kidner, Vasco Koch, Arian Köhler, F Bernhard Kraus, H Michael G Lattorff, Megan Leask, Gabrielle A Lockett, Eamonn B Mallon, David S Marco Antonio, Monika Marxer, Ivan Meeus, Robin F A Moritz, Ajay Nair, Kathrin Näpflin, Inga Nissen, Jinzhi Niu, Francis M Nunes, John G Oakeshott, Amy Osborne, Marianne Otte, Daniel G Pinheiro, Nina Rossié, Olav Rueppell, Carolina G Santos, Regula Schmid-Hempel, Björn D Schmitt, Christina Schulte, Zilá L P Simões, Michelle P Soares, Luc Swevers, Eva C Winnebeck, Florian Wolschin, Na Yu, Evgeny M Zdobnov, Peshtewani K Aqrawi, Kerstin P Blankenburg, Marcus Coyle, Liezl Francisco, Alvaro G Hernandez, Michael Holder, Matthew E Hudson, LaRonda Jackson, Joy Jayaseelan, Vandita Joshi, Christie Kovar, Sandra Lee, Robert Mata, Tittu Mathew, Irene F Newsham, Robin Ngo, Geoffrey Okwuonu, Christopher Pham, Pu, Nehad Saada, Jireh Santibanez, DeNard Simmons, Rebecca Thornton, Aarti Venkat, Kimberly O Walden, Yuan-Qing Wu, Griet Debyser, Bart Devreese, Claire Asher, Julie Blommaert, Ariel D Chipman, Lars Chittka, Bertrand Fouks, Jisheng Liu, Meaghan P O'Neill, Seirian Sumner, Daniela Puiu, Jiaxin Qu, Steven L Salzberg, Steven E Scherer, Donna Muzny, Stephen Richards, Gene E Robinson, Richard A Gibbs, Paul Schmid-Hempel, and Kim C Worley

    Genome biology 16:76 (2015) PMID 25908251 PMCID PMC4414376

    The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies. Bumblebees are also invaluable natural and agricultural pollinators, and there is widespre...
  12. Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions.

    Nature Communications 6:7344 (2015) PMID 26108605 PMCID PMC4491171

    Lucilia cuprina is a parasitic fly of major economic importance worldwide. Larvae of this fly invade their animal host, feed on tissues and excretions and progressively cause severe skin disease (myiasis). Here we report the sequence and annotation of the 458-megabase draft genome of Lucilia cup...
  13. A Massive Expansion of Effector Genes Underlies Gall-Formation in the Wheat Pest Mayetiola destructor

    Current Biology (2014)

    • The plant galling Mayetiola destructor genome is replete with effector genes • The SSGP-71 effector gene family is the largest known arthropod gene family. ...
  14. The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera.

    Nature Communications 5:4737 (2014) PMID 25189940 PMCID PMC4164777

    Previous studies have reported that chromosome synteny in Lepidoptera has been well conserved, yet the number of haploid chromosomes varies widely from 5 to 223. Here we report the genome (393 Mb) of the Glanville fritillary butterfly (Melitaea cinxia; Nymphalidae), a widely recognized model spe...
  15. Finding the missing honey bee genes: lessons learned from a genome upgrade.

    BMC Genomics 15:86 (2014) PMID 24479613 PMCID PMC4028053

    The first generation of genome sequence assemblies and annotations have had a significant impact upon our understanding of the biology of the sequenced species, the phylogenetic relationships among species, the study of populations within and across species, and have informed the biology of huma...
  16. Genome analysis of a major urban malaria vector mosquito, Anopheles stephensi.

    Genome biology 15(9):459 (2014) PMID 25244985

    Anopheles stephensi is the key vector of malaria throughout the Indian subcontinent and Middle East and an emerging model for molecular and genetic studies of mosquito-parasite interactions. The type form of the species is responsible for the majority of urban malaria transmission across its ran...
  17. The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera.

    Nature Communications 5:4737 (2014) PMID 25189940 PMCID PMC4164777

    Previous studies have reported that chromosome synteny in Lepidoptera has been well conserved, yet the number of haploid chromosomes varies widely from 5 to 223. Here we report the genome (393 Mb) of the Glanville fritillary butterfly (Melitaea cinxia; Nymphalidae), a widely recognized model spe...
  18. Genome analysis of a major urban malaria vector mosquito, Anopheles stephensi.

    Genome biology 15(9):459 (2014) PMID 25244985 PMCID PMC4195908

    Anopheles stephensi is the key vector of malaria throughout the Indian subcontinent and Middle East and an emerging model for molecular and genetic studies of mosquito-parasite interactions. The type form of the species is responsible for the majority of urban malaria transmission across its ran...
  19. Finding the missing honey bee genes: lessons learned from a genome upgrade.

    BMC Genomics 15:86 (2014) PMID 24479613 PMCID PMC4028053

    The first generation of genome sequence assemblies and annotations have had a significant impact upon our understanding of the biology of the sequenced species, the phylogenetic relationships among species, the study of populations within and across species, and have informed the biology of huma...
  20. Phylogenetic analysis of the oriental-Palearctic-Afrotropical members of Anopheles (Culicidae: Diptera) based on nuclear rDNA and mitochondrial DNA characteristics.

    Japanese Journal of Infectious Diseases 67(5):361 (2014) PMID 25241686

    The phylogenetic relationships of Anopheles spp. at the junction of Oriental, Palearctic, and Afrotropical regions in the Iranian plateau were investigated using molecular markers. A 711-bp mitochondrial DNA cytochrome oxidase C subunit I (COI) fragment and the entire second internal transcribed...
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