1. Antarctica challenges the new horizons in predictive, preventive, personalized medicine: preliminary results and attractive hypotheses for multi-disciplinary prospective studies in the Ukrainian "Akademik Vernadsky" station.

    The EPMA Journal 7:11 (2016) PMID 27247701 PMCID PMC4886406

    Antarctica is a unique place to study the health condition under the influence of environmental factors on the organism in pure form. Since the very beginning of the scientific presence of Ukraine in the Antarctic, biomedical research has been developed for the monitoring of individual biomarker...
  2. Erratum to: Antarctica challenges the new horizons in predictive, preventive, personalized medicine: preliminary results and attractive hypotheses for multi-disciplinary prospective studies in the Ukrainian "Akademik Vernadsky" station.

    The EPMA Journal 7:17 (2016) PMID 27437067 PMCID PMC4949876

    [This corrects the article DOI: 10.1186/s13167-016-0060-8.].
  3. Antioxidative effects of cerium dioxide nanoparticles ameliorate age-related male infertility: optimistic results in rats and the review of clinical clues for integrative concept of men health and fertility.

    The EPMA Journal 6(1):12 (2015) PMID 26097523 PMCID PMC4475301

    Male infertility has largely idiopathic, multifactorial origin. Oxidative stress is a major factor that affects spermatogenesis, in particular in aging. Cerium dioxide nanoparticles (CNPs) due to their antioxidative properties are promising to impact on the development of male infertility. The a...
  4. The role of beneficial bacteria wall elasticity in regulating innate immune response.

    The EPMA Journal 6(1):13 (2015) PMID 26110044 PMCID PMC4479350

    Probiotics have great potential to contribute to development of healthy dietary regimes, preventive care, and an integrated approach to immunity-related disease management. The bacterial wall is a dynamic entity, depending on many components and playing an essential role in modulating immune res...
  5. Probiotics and immunity: provisional role for personalized diets and disease prevention.

    The EPMA Journal 6(1):14 (2015) PMID 26221192 PMCID PMC4517425

    There is great interest in the interaction between diet and immune system and concomitantly in the potential of probiotic bacteria, especially given recent advances in understanding of gut microbiota effects on health in the context of microbiome research. Following our recent study on bacterial...
  6. Assessing value of innovative molecular diagnostic tests in the concept of predictive, preventive, and personalized medicine.

    The EPMA Journal 6:19 (2015) PMID 26425215 PMCID PMC4588236

    Molecular diagnostic tests drive the scientific and technological uplift in the field of predictive, preventive, and personalized medicine offering invaluable clinical and socioeconomic benefits to the key stakeholders. Although the results of diagnostic tests are immensely influential, molecula...
  7. Nanocrystalline cerium dioxide efficacy for gastrointestinal motility: potential for prokinetic treatment and prevention in elderly.

    The EPMA Journal 6(1):6 (2015) PMID 25815090 PMCID PMC4374531

    Constipation is a common condition, with prevalence after 65 years, is a major colorectal cancer risk factor. Recent works have demonstrated advances in personalized, preventive nanomedicine, leading to the construction of new materials and nanodrugs, in particular, nanocrystalline cerium dioxid...
  8. Development of biomarker panel to predict, prevent and create treatments tailored to the persons with human papillomavirus-induced cervical precancerous lesions.

    The EPMA Journal 5(1):1 (2014) PMID 24386936 PMCID PMC3901026

    Human papillomavirus (HPV) induce many cancer conditions and cause cervical cancer, second in frequency of malignant disease in women.The aim was to develop biomarker panel for HPV-induced cervical precancerous diseases in patients infected with herpes simplex virus (HSV). The study involved 71 ...
  9. The efficacy of probiotics for monosodium glutamate-induced obesity: dietology concerns and opportunities for prevention.

    The EPMA Journal 5(1):2 (2014) PMID 24410812 PMCID PMC3922789

    Obesity becomes endemic today. Monosodium glutamate was proved as obesogenic food additive. Probiotics are discussed to impact on obesity development. The aim was to study the effects of probiotics on the development of monosodium glutamate (MSG)-induced obesity in rats. We included 45 Wistar ma...
  10. Predictive diagnosis of endometrial hyperplasia and personalized therapeutic strategy in women of fertile age.

    The EPMA Journal 4(1):24 (2013) PMID 24314145 PMCID PMC3866390

    Endometrial hyperplasia has a high risk for malignant transformation and relapses; existing mini-invasive treatments may lead to irrevocable endometrium destruction. The aims were to analyze receptor systems in endometrial hyperplasia, to evaluate the capabilities of ultrasonography, sonoelastog...
  11. Development and testing of gold nanoparticles for drug delivery and treatment of heart failure: a theranostic potential for PPP cardiology.

    The EPMA Journal 4(1):20 (2013) PMID 23889805 PMCID PMC3751918

    Nanoscale gold particles (AuNPs) have wide perspectives for biomedical applications because of their unique biological properties, as antioxidative activity and potentials for drug delivery. The aim was to test effects of AuNPs using suggested heart failure rat model to compare with proved medic...
  12. Gold nanoparticles - the theranostic challenge for PPPM: nanocardiology application.

    The EPMA Journal 4(1):18 (2013) PMID 23800174 PMCID PMC3702527

    The article overviews the potential biomedical applications of nanoscale gold particles for predictive, preventive and personalised nanomedicine in cardiology. The review demonstrates the wide opportunities for gold nanoparticles due to their unique biological properties. The use of gold nanopar...
  13. Evidence-based pain management: is the concept of integrative medicine applicable?

    The EPMA Journal 3(1):13 (2012) PMID 23088743 PMCID PMC3533862

    This article is dedicated to the concept of predictive, preventive, and personalized (integrative) medicine beneficial and applicable to advance pain management, overviews recent insights, and discusses novel minimally invasive tools, performed under ultrasound guidance, enhanced by model-guide...
  14. The use of trigger point "dry" needling under ultrasound guidance for the treatment of myofascial pain (technological innovation and literature review).

    Likars'ka sprava / Ministerstvo okhorony zdorov... (5-6):56 (2010) PMID 21485754

    The aim of the study was to examine the use of trigger point dry needling under ultrasound guidance and myofascial release for the treatment of myofascial pain and to increase the provability of the puncture treatment by visual verification. A review of modern and traditional approaches to myofa...