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  1. D1 dopamine receptor coupling to PLCβ regulates forward locomotion in mice.

    Journal of Neuroscience 33(46):18125 (2013) PMID 24227722 PMCID PMC3828465

    We report that stimulation of dopamine receptor signaling in vivo with systemic administration of apomorphine, amphetamine, and cocaine leads to increased production of inositol triphosphate (IP3) in the mouse striatum. Using selective antagonists and dopamine D1 and D2 receptor knock-out animals, w...
  2. The cost-effectiveness of palivizumab for respiratory syncytial virus prophylaxis in premature infants with a gestational age of 32-35 weeks...

    Current Medical Research and Opinion 24(11):3223 (2008) PMID 18928643

    The expected costs were higher for palivizumab prophylaxis as compared with no prophylaxis. The incremental cost-effectiveness ratio (ICER) for the base-case scenario was $20 924 per QALY after discounting, which is considered cost-effective in Canada. When the uncertainty of the input parameter ass...
  3. Assessing the validity of deriving clinical dementia rating (CDR) global scores from independently-obtained functional rating scale (FRS) sc...

    International Journal of Geriatric Psychiatry 24(10):1174 (2009) PMID 19768698

  4. Comparison of the cost of hospitalization for respiratory syncytial virus disease versus palivizumab prophylaxis in Canadian Inuit infants.

    Pediatric Infectious Disease Journal 28(8):702 (2009) PMID 19461555

    The objectives were to compare actual respiratory syncytial virus (RSV) hospitalization rates and costs in a cohort of Inuit infants to hypothetical palivizumab prophylaxis strategies for infants of all gestational ages in the Eastern Canadian Arctic. Incidence and costs of RSV hospitalization were...