1. Arginase inhibition protects against hypoxia‑induced pulmonary arterial hypertension.

    Molecular Medicine Reports 12(3):4743 (2015) PMID 26126810

    The present study aimed to determine the role of arginase (Arg) in pulmonary arterial hypertension (PAH). In vitro, human pulmonary artery smooth muscle cells (HPASMCs) were cultured under hypoxic conditions with, or without, the Arg inhibitor, S‑(2‑boronoethyl)‑l‑cysteine (BEC), for 48 h, follo...
  2. Pure red cell aplasia due to anti-erythropoietin antibodies or isoniazid? A case report from a 94-year-old man.

    Aging Clinical and Experimental Research 27(4):561 (2015) PMID 25597021

  3. SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor.

    Journal of Biological Chemistry 290(29):17894 (2015) PMID 26032413 PMCID PMC4505038

    Appropriate cellular signaling is essential to control cell proliferation, differentiation, and cell death. Aberrant signaling can have devastating consequences and lead to disease states, including cancer. The transforming growth factor-β (TGF-β) signaling pathway is a prominent signaling pathw...
  4. Mechanical degradation of graphene by epoxidation: insights from first-principles calculations.

    Physical Chemistry Chemical Physics 17(29):19484 (2015) PMID 26143751

    Oxidation is a major cause for the degradation of materials including graphene, where epoxidation (forming the C-O-C bond) is very common. In addition, graphene oxide, in which the epoxy group is one of the two major functional groups (the other is hydroxy), is an important precursor material us...
  5. How Can Single Sensory Neurons Predict Behavior?

    Neuron 87(2):411 (2015) PMID 26182422

    Single sensory neurons can be surprisingly predictive of behavior in discrimination tasks. We propose this is possible because sensory information extracted from neural populations is severely restricted, either by near-optimal decoding of a population with information-limiting correlations or b...
  6. CD4(+) Foxp3(+) regulatory T-cell number increases in the gastric tissue of C57BL/6 mice infected with Helicobacter pylori.

    Acta Pathologica Microbiologica Scandinavica Se... 123(7):571 (2015) PMID 26010562

    Helicobacter pylori (H. pylori), one of the most common infections, is associated with various clinical outcomes. In addition to inducing inflammation, immunological clearance of the pathogen is often incomplete. Regulatory T cells (Treg cells) have been recently demonstrated to play an importan...
  7. Hybrid plasmonic waveguide made of a nanofiber attached to a metal film.

    Optics Express 23(13):16984 (2015) PMID 26191708

    We report a hybrid plasmonic waveguide consisting of a nanofiber coupled with a copper film on a silicon substrate. The nanofiber can be flexibly placed on the copper film to generate a highly localized optical field. Due to the easy attachment of the nanofiber to the metal surface, it is conven...
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  8. Continuous and dynamic spectral tuning of single nanowire lasers with subnanometer resolution using hydrostatic pressure.

    Nanoscale 7(21):9581 (2015) PMID 25952721

    We report continuous, dynamic, reversible, and widely tunable lasing from 367 to 337 nm from single GaN nanowires (NWs) by applying hydrostatic pressure up to ∼7 GPa. The GaN NW lasers, with heights of 4-5 μm and diameters ∼140 nm, are fabricated using a lithographically defined two-step top-dow...
  9. Effectiveness of bone marrow mononuclear cells delivered through a graft vessel for patients with previous myocardial infarction and chronic heart failure: an echocardiographic study of left ventricular remodeling.

    Medical Ultrasonography 17(2):160 (2015) PMID 26052565

    The graft of stem cells to treat ischemic cardiomyopathy is popular in many clinical trials. The aim of this study was to evaluate the effectiveness of isolated coronary artery bypass graft combined with bone marrow mononuclear cells (BMMNC) delivered through graft vessels to improve left ventri...
  10. Investigations of thermal and flow behavior of bifurcations and bends in fractal-like microchannel networks: Secondary flow and recirculation flow

    International Journal of Heat and Mass Transfer 85:723 (2015)

    In this work, the secondary flow and recirculation flow motions initiated at the bifurcations and bends in symmetric fractal-like microchannel networks with two branching levels were studied through three-dimensional simulations. The effects of Reynolds number and aspect ratio on the v...
  11. Helicobacter pylori induces IL-1β and IL-18 production in human monocytic cell line through activation of NLRP3 inflammasome via ROS signaling pathway.

    Pathogens and Disease 73(4) (2015) PMID 25834143

    This study investigated whether Helicobacter pylori could activate the nucleotide-binding oligomerization domain-like receptor (NLR) family, pyrin domain-containing 3 (NLRP3) inflammasome in human macrophages and the involvement of reactive oxygen species (ROS) in inflammasome activation. Phorbo...
  12. Chemoembolization of recurrent hepatoma after curative resection: prognostic factors.

    American Journal of Roentgenology 204(6):1322 (2015) PMID 26001244

    The long-term prognosis after hepatic resection for the treatment of hepatocellular carcinoma (HCC) has been disappointing because of the high recurrence rates in the remnant liver, which constitutes the major cause of death. The purpose of this study was to identify the prognostic factors for o...
  13. Rab3 is involved in cellular immune responses of the cotton bollworm, Helicoverpa armigera

    Developmental & Comparative Immunology 50(2):78 (2015)

    • Knockdown of Ha-Rab3 led to reduced phagocytosis activities of hemocytes. • Knockdown of Ha-Rab3 led to reduced nodule formation. ...
  14. Effects of Bone Marrow Mononuclear Cells Delivered through a Graft Vessel for Patients with Previous Myocardial Infarction and Chronic Heart Failure: An Echocardiographic Study of Left Ventricular Function.

    Echocardiography 32(6):937 (2015) PMID 25418212

    The graft of stem cells to treat ischemic cardiomyopathy is popular in many clinical trials. The aim of this study was to evaluate the effectiveness of isolated coronary artery bypass graft combined with bone marrow mononuclear cells (BMMNC) delivered through graft vessels to improve left ventri...
  15. Starfish-shaped Co3O4/ZnFe2O4 Hollow Nanocomposite: Synthesis, Supercapacity, and Magnetic Properties.

    ACS Applied Materials & Interfaces 7(18):9972 (2015) PMID 25877380

    A novel starfish-shaped porous Co3O4/ZnFe2O4 hollow nanocomposite was fabricated for the first time by a facile and stepwise hydrothermal approach, utilizing metal-organic frameworks as precursors and sacrificial templates. The morphology evolution in the synthetic process upon reaction time and...
  16. Design, synthesis, biological evaluation and molecular docking studies of phenylpropanoid derivatives as potent anti-hepatitis B virus agents.

    European Journal of Medicinal Chemistry 95:473 (2015) PMID 25847765

    A series of phenylpropanoid derivatives were synthesized, and their anti-hepatitis B virus (HBV) activity was evaluated in HepG 2.2.15 cells. Most of the synthesized derivatives showed effective anti-HBV activity. Of these compounds, compound 4c-1 showed the most potent anti-HBV activity, demons...
  17. Molecular characterization of a peptidoglycan recognition protein from the cotton bollworm, Helicoverpa armigera and its role in the prophenoloxidase activation pathway

    Molecular Immunology 65(1):123 (2015)

    • HaPGRP-A can bind and agglutinate bacteria. • HaPGRP-A is involved in the PPO activation pathway. • ...
  18. A novel driving mode for ion shutter based on alternating current superposition and its application to ion mobility spectrometry

    Sensors and Actuators B: Chemical 211:102 (2015)

    • A novel driving mode for the ion shutter based on the alternating current (AC) superposition was designed. • A simple and low cost power supply for controlling i...
  19. Biocides in the Yangtze River of China: Spatiotemporal distribution, mass load and risk assessment

    Environmental Pollution 200:53 (2015)

    Nineteen biocides were investigated in the Yangtze River to understand their spatiotemporal distribution, mass loads and ecological risks. Fourteen biocides were detected, with the highest concentrations up to 166 ng/L for DEET in surface water, and 54.3 ng/g dry weight (dw) for triclo...
  20. A 2.45-GHz W-level output power CMOS power amplifier with adaptive bias and integrated diode linearizer

    Microelectronics Journal 46(5):327 (2015)

    A high-linearity CMOS power amplifier (PA) operating at 2.45GHz for WLAN applications with adaptive bias and an integrated diode linearizer is presented. The PA adopts adaptive bias scheme to adjust the gate bias voltage of power transistors by tracking the output power of the first di...