1. Axial Current Generation by P-Odd Domains in QCD Matter.

    Physical Review Letters 114(25):252301 (2015) PMID 26197121

    The dynamics of topological domains which break parity (P) and charge-parity (CP) symmetry of QCD are studied. We derive in a general setting that those local domains will generate an axial current and quantify the strength of the induced axial current. Our findings are verified in a top-down ho...
  2. EpiProfile Quantifies Histone Peptides With Modifications by Extracting Retention Time and Intensity in High-resolution Mass Spectra.

    Molecular & Cellular Proteomics 14(6):1696 (2015) PMID 25805797 PMCID PMC4458730

    Histone post-translational modifications contribute to chromatin function through their chemical properties which influence chromatin structure and their ability to recruit chromatin interacting proteins. Nanoflow liquid chromatography coupled with high resolution tandem mass spectrometry (nanoL...
  3. Study on thermal properties of graphene foam/graphene sheets filled polymer composites

    Composites Part A: Applied Science and Manufact... 72:200 (2015)

    The polymer composites composed of graphene foam (GF), graphene sheets (GSs) and pliable polydimethylsiloxane (PDMS) were fabricated and their thermal properties were investigated. Due to the unique interconnected structure of GF, the thermal conductivity of GF/PDMS composite reaches 0...
  4. Drawbacks in the use of unconventional hydrophobic anhydrides for histone derivatization in bottom-up proteomics PTM analysis.

    Proteomics 15(9):1459 (2015) PMID 25641854 PMCID PMC4441824

    MS-based proteomics has become the most utilized tool to characterize histone PTMs. Since histones are highly enriched in lysine and arginine residues, lysine derivatization has been developed to prevent the generation of short peptides (<6 residues) during trypsin digestion. One of the most ado...
  5. Fluid flow and heat transfer characteristics of liquid cooling microchannels in LTCC multilayered packaging substrate

    International Journal of Heat and Mass Transfer 84:339 (2015)

    The fluid flow and heat transfer of liquid cooling microchannels embedded in low temperature co-fired ceramic (LTCC) multilayered electronic packaging substrate have been investigated. Four cooling systems were supplied for high power application of 100W LED lamp, including aluminum fi...
  6. Optimization of ultrasound extraction of Alisma orientalis polysaccharides by response surface methodology and their antioxidant activities.

    Carbohydrate polymers 119:101 (2015) PMID 25563949

    Rhizoma alismatis (the rhizome of Alisma orientalis) polysaccharides (RAP) have been reported to have a variety of important biological activities. However, effective extraction of RAP has been an unsolved issue. In this study, we used an ultrasound method for high yield extraction of RAP and op...
  7. Optimization of ultrasound extraction of Alisma orientalis polysaccharides by response surface methodology and their antioxidant activities.

    Carbohydrate polymers 119:101 (2015) PMID 25563949

    Rhizoma alismatis (the rhizome of Alisma orientalis) polysaccharides (RAP) have been reported to have a variety of important biological activities. However, effective extraction of RAP has been an unsolved issue. In this study, we used an ultrasound method for high yield extraction of RAP and op...
  8. Quantitative proteomic analysis of histone modifications.

    Chemical Reviews 115(6):2376 (2015) PMID 25688442 PMCID PMC4502928

  9. Bottom-up and middle-down proteomics have comparable accuracies in defining histone post-translational modification relative abundance and stoichiometry.

    Analytical chemistry 87(6):3129 (2015) PMID 25719549 PMCID PMC4469134

    Histone proteins are key components of chromatin. Their N-terminal tails are enriched in combinatorial post-translational modifications (PTMs), which influence gene regulation, DNA repair, and chromosome condensation. Mass spectrometry (MS)-based middle-down proteomics has emerged as a technique...
  10. N-Cadherin Induction by ECM Stiffness and FAK Overrides the Spreading Requirement for Proliferation of Vascular Smooth Muscle Cells

    Cell Reports 10(9):1477 (2015)

    In contrast to the accepted pro-proliferative effect of cell-matrix adhesion, the proliferative effect of cadherin-mediated cell-cell adhesion remains unresolved. Here, we studied the effect of N-cadherin on cell proliferation in the vasculature. We show that N-cadherin is induced in s...
  11. Tissue engineering of the temporomandibular joint disc: current status and future trends.

    International Journal of Artificial Organs 38(2):55 (2015) PMID 25744198

    Temporomandibular joint disorders are extremely prevalent and there is no ideal treatment clinically for the moment. For severe cases, a discectomy often need to be performed, which will further result in the development of osteoarthritis. In the past thirty years, tissue engineering has provide...
  12. Subsequent risk of nasopharyngeal carcinoma among patients with allergic rhinitis: A nationwide population-based cohort study.

    Head & Neck (Print Edition) 37(3):413 (2015) PMID 24435940

    The purpose of this study was to examine the risk of nasopharyngeal carcinoma (NPC) after a diagnosis of allergic rhinitis. We identified 67,532 patients with allergic rhinitis (allergic rhinitis cohort) and a 135,064 control cohort with the same mean age and sex ratio by using a Taiwan Longitud...
  13. Production and elliptic flow of dileptons and photons in a matrix model of the quark-gluon plasma.

    Physical Review Letters 114(7):072301 (2015) PMID 25763954

    We consider a nonperturbative approach to the thermal production of dileptons and photons at temperatures near the critical temperature in QCD. The suppression of colored excitations at low temperature is modeled by including a small value of the Polyakov loop, in a "semi"-quark-gluon plasma (QG...
  14. Genome-wide Association Study of Survival in Early-stage Non-Small Cell Lung Cancer.

    Annals of Surgical Oncology 22(2):630 (2015) PMID 25145502

    Lung cancer, especially non-small cell lung cancer (NSCLC), is the leading cause of cancer-related deaths all over the world. Studies have indicated that molecular biomarkers, including genetic variants, may provide additional values for the targeted treatments and clinical outcomes of NSCLC pat...
  15. Genome-wide association study of survival in early-stage non-small cell lung cancer.

    Annals of Surgical Oncology 22(2):630 (2015) PMID 25145502

    Lung cancer, especially non-small cell lung cancer (NSCLC), is the leading cause of cancer-related deaths all over the world. Studies have indicated that molecular biomarkers, including genetic variants, may provide additional values for the targeted treatments and clinical outcomes of NSCLC pat...
  16. Hyperlipidemia and statins affect neurological outcome in lumbar spine injury.

    International Journal of Environmental Research... 12(1):402 (2015) PMID 25568970

    The disabling pathophysiologic effects of lipid and neuroprotective effects of statins have recently been demonstrated for acute spinal cord injuries in animal models. This large scale population-based study aimed to investigate the effect hyperlipidemia and the use of statins in patients with l...
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  17. Hyperlipidemia and statins affect neurological outcome in lumbar spine injury.

    International Journal of Environmental Research... 12(1):402 (2015) PMID 25568970 PMCID PMC4306869

    The disabling pathophysiologic effects of lipid and neuroprotective effects of statins have recently been demonstrated for acute spinal cord injuries in animal models. This large scale population-based study aimed to investigate the effect hyperlipidemia and the use of statins in patients with l...
  18. Individual-level analysis of differential expression of genes and pathways for personalized medicine.

    PMID 25165092

    The differential expression analysis focusing on inter-group comparison can capture only differentially expressed genes (DE genes) at the population level, which may mask the heterogeneity of differential expression in individuals. Thus, to provide patient-specific information for personalized m...
  19. Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI.

    PLoS ONE 10(7):e0133362 (2015) PMID 26207898 PMCID PMC4514813

    The TGF-b superfamily cytokine MIC-1/GDF15 circulates in the blood of healthy humans. Its levels rise substantially in cancer and other diseases and this may sometimes lead to development of an anorexia/cachexia syndrome. This is mediated by a direct action of MIC-1/GDF15 on feeding centres in t...
  20. Tissue distribution study of salvianolic acid B long-circulating liposomes in mice by UPLC-MS/MS determination.

    Pakistan journal of pharmaceutical sciences 28(1):213 (2015) PMID 25553697

    In targeting delivery system research on salvianolic acid B, it's vital but hard to evaluate the tissue distribution for its low concentrations in tissues. So the simple, rapid, selective and sensitive UPLC-MS/MS method was provided hereby to determine the concentration of salvianolic acid B in ...