1. A Man with Diarrhea and Back Pain

    New England Journal of Medicine 372(15):e21 (2015) PMID 25839865

    This interactive feature presents the case of a 43-year-old man with a 6-week history of constant and diffuse abdominal pain and diarrhea six to seven times daily. Test your diagnostic and therapeutic skills at NEJM.org. A 43-year-old man presented with a 6-week history of ab...
  2. A Man with Diarrhea and Back Pain

    New England Journal of Medicine 372(15):e21 (2015) PMID 25853769

    This interactive feature presents the case of a 43-year-old man with a 6-week history of constant and diffuse abdominal pain and diarrhea six to seven times daily. Test your diagnostic and therapeutic skills at NEJM.org. A 43-year-old man presented with a 6-week history of ab...
  3. A Man with Diarrhea and Back Pain

    New England Journal of Medicine 372(15):e21 (2015) PMID 25839865

    This interactive feature presents the case of a 43-year-old man with a 6-week history of constant and diffuse abdominal pain and diarrhea six to seven times daily. Test your diagnostic and therapeutic skills at NEJM.org. A 43-year-old man presented with a 6-week history of ab...
  4. A Man with Diarrhea and Back Pain

    New England Journal of Medicine 372(15):e21 (2015) PMID 25853769

    This interactive feature presents the case of a 43-year-old man with a 6-week history of constant and diffuse abdominal pain and diarrhea six to seven times daily. Test your diagnostic and therapeutic skills at NEJM.org. A 43-year-old man presented with a 6-week history of ab...
  5. A Man with Diarrhea and Back Pain

    New England Journal of Medicine 372(15):e21 (2015) PMID 25853769

    This interactive feature presents the case of a 43-year-old man with a 6-week history of constant and diffuse abdominal pain and diarrhea six to seven times daily. Test your diagnostic and therapeutic skills at NEJM.org. A 43-year-old man presented with a 6-week history of ab...
  6. Evidence for a Dualistic Model of High-grade Serous Carcinoma: BRCA Mutation Status, Histology, and Tubal Intraepithelial Carcinoma.

    The American Journal of Surgical Pathology 39(3):287 (2015) PMID 25581732

    Most early adnexal carcinomas detected in asymptomatic women with germline BRCA mutations (BRCA) present as serous tubal intraepithelial carcinomas (STIC). However, STICs are found in only ∼40% of symptomatic high-grade serous carcinomas (HGSCs) and less frequently in pseudoendometrioid variants...
  7. Evidence for a dualistic model of high-grade serous carcinoma: BRCA mutation status, histology, and tubal intraepithelial carcinoma.

    The American Journal of Surgical Pathology 39(3):287 (2015) PMID 25581732

    Most early adnexal carcinomas detected in asymptomatic women with germline BRCA mutations (BRCA) present as serous tubal intraepithelial carcinomas (STIC). However, STICs are found in only ∼40% of symptomatic high-grade serous carcinomas (HGSCs) and less frequently in pseudoendometrioid variants...
  8. Longitudinal changes in brains of patients with fluent primary progressive aphasia.

    Brain and Language 131:11 (2014) PMID 23796527

    Primary progressive aphasia (PPA) is a rare clinical dementia syndrome with predominant, progressive language impairment. Clinical symptoms, linguistic impairment and the course of the disease may vary considerably between patients. In order to capture these aspects, longitudinal assessments of ...
  9. Longitudinal changes in brains of patients with fluent primary progressive aphasia.

    Brain and Language 131:11 (2014) PMID 23796527

    Primary progressive aphasia (PPA) is a rare clinical dementia syndrome with predominant, progressive language impairment. Clinical symptoms, linguistic impairment and the course of the disease may vary considerably between patients. In order to capture these aspects, longitudinal assessments of ...
  10. Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis

    Journal of Allergy and Clinical Immunology 131(2):451 (2013)

    Background Sensitization to food antigen can occur through cutaneous exposure.
  11. Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis.

    Journal of Allergy and Clinical Immunology 131(2):451 (2013) PMID 23374269 PMCID PMC3587010

    Sensitization to food antigen can occur through cutaneous exposure. We sought to test the hypothesis that epicutaneous sensitization with food antigen predisposes to IgE-mediated anaphylaxis on oral allergen challenge. BALB/c mice were epicutaneously sensitized by repeated application of ovalbum...
  12. Epicutaneous Sensitization Results in IgE-Dependent Intestinal Mast Cell Expansion and Food Anaphylaxis

    Journal of Allergy and Clinical Immunology 131(2):AB218 (2013)

  13. Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis.

    Journal of Allergy and Clinical Immunology 131(2):451 (2013) PMID 23374269 PMCID PMC3587010

    Sensitization to food antigen can occur through cutaneous exposure. We sought to test the hypothesis that epicutaneous sensitization with food antigen predisposes to IgE-mediated anaphylaxis on oral allergen challenge. BALB/c mice were epicutaneously sensitized by repeated application of ovalbum...
  14. The time course of neurolinguistic and neuropsychological symptoms in three cases of logopenic primary progressive aphasia

    Neuropsychologia 50(7):1708 (2012) PMID 22484080

    Highlights ► The study provides a novel longitudinal account of the progress of fluent PPA. ► Deteriorations not only in language but also attention and praxis are reported. ► Exemplary data for the development of a single PPA case over 46 months are given. ► One PPA patient ...
  15. The time course of neurolinguistic and neuropsychological symptoms in three cases of logopenic primary progressive aphasia

    Neuropsychologia 50(7):1708 (2012) PMID 22484080

    Highlights ► The study provides a novel longitudinal account of the progress of fluent PPA. ► Deteriorations not only in language but also attention and praxis are reported. ► Exemplary data for the development of a single PPA case over 46 months are given. ► One PPA patient ...
  16. The time course of neurolinguistic and neuropsychological symptoms in three cases of logopenic primary progressive aphasia.

    Neuropsychologia 50(7):1708 (2012) PMID 22484080

    Primary progressive aphasia (PPA) is a rare clinical dementia syndrome affecting predominantly language abilities. Word-finding difficulties and comprehension deficits despite relatively preserved cognitive functions are characteristic symptoms during the first two years, and distinguish PPA fro...
  17. The time course of neurolinguistic and neuropsychological symptoms in three cases of logopenic primary progressive aphasia

    Neuropsychologia 50(7):1708 (2012)

    Highlights ► The study provides a novel longitudinal account of the progress of fluent PPA. ► Deteriorations not only in language but also attention and praxis are reported. ► Exemplary data for the development of a single PPA case over 46 months are given. ► One PPA patient ...
  18. Longitudinal changes in brains of patients with fluent primary progressive aphasia

    Brain and Language (2011)

    • Longitudinal analysis of performance, brain structure, and function in PPA over 1year. • Consistent high-level performance in a visual lexical word-pseudoword de...
  19. Longitudinal changes in brains of patients with fluent primary progressive aphasia

    Brain and Language 131 (2011) PMID 23796527

    • Longitudinal analysis of performance, brain structure, and function in PPA over 1year. • Consistent high-level performance in a visual lexical word-pseudoword de...
  20. Cystatin C deficiency promotes inflammation in angiotensin II-induced abdominal aortic aneurisms in atherosclerotic mice.

    The American Journal of Pathology 177(1):456 (2010) PMID 20472891 PMCID PMC2893687

    An imbalance between cysteinyl cathepsins and their principal endogenous inhibitor cystatin C (CystC) may favor proteolysis in the pathogenesis of human abdominal aortic aneurysms (AAA), yet a direct role of CystC in AAA remains unproven. This study used CystC and apolipoprotein E (ApoE) compoun...